| 1592356 | Amtn | amelotin | INVOLVED IN odontogenesis of dentin-containing tooth; amelogenesis (ortholog); enamel mineralization (ortholog); ASSOCIATED WITH amelogenesis imperfecta type 3A (ortholog); amelogenesis imperfecta type 3B (ortholog); FOUND IN basement membrane; cell-cell junction; extracellular matrix; INTERACTS WIT H 17beta-estradiol; bisphenol A; cadmium dichloride | 14 | 19932664 | 19945223 | Rat | 49 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1604908 | AMTN | amelotin | The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (E NAM; MIM 606585), and ameloblastin (AMBN; MIM 601259), in the organic enamel matrix. Amelotin is specifically expressed in maturation-stage ameloblasts (Iwasaki et al., 2005 [PubMed 16304441]).[supplied by OMIM, Mar 2008] | 4 | 70518569 | 70532743 | Human | 50 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1614326 | Amtn | amelotin | Involved in odontogenesis of dentin-containing tooth and positive regulation of enamel mineralization. Located in basement membrane and cell-cell junction. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 3B. Orthologous to human AMTN (a melotin). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 88523967 | 88533775 | Mouse | 57 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8843566 | Amtn | amelotin | INVOLVED IN amelogenesis (ortholog); enamel mineralization (ortholog); odontogenesis of dentin-containing tooth (ortholog); ASSOCIATED WITH amelogenesis imperfecta type 3A (ortholog); amelogenesis imperfecta type 3B (ortholog); FOUND IN basement membrane (ortholog); cell-cell junction (ortholog); ex tracellular matrix (ortholog) | NW_004955447 | 2422189 | 2433633 | Chinchilla | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11684551 | AMTN | amelotin | INVOLVED IN amelogenesis (ortholog); enamel mineralization (ortholog); ASSOCIATED WITH amelogenesis imperfecta type 3A (ortholog); amelogenesis imperfecta type 3B (ortholog); FOUND IN basement membrane (inferred); cell-cell junction (inferred); extracellular matrix (inferred) | 4 | 53691674 | 53705831 | Bonobo | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12072321 | AMTN | amelotin | INVOLVED IN amelogenesis (ortholog); enamel mineralization (ortholog); ASSOCIATED WITH amelogenesis imperfecta type 3A (ortholog); amelogenesis imperfecta type 3B (ortholog); FOUND IN basement membrane (inferred); cell-cell junction (inferred); extracellular matrix (inferred) | 13 | 59855278 | 59867133 | Dog | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12603978 | Amtn | amelotin | INVOLVED IN amelogenesis (ortholog); enamel mineralization (ortholog); ASSOCIATED WITH amelogenesis imperfecta type 3A (ortholog); amelogenesis imperfecta type 3B (ortholog); FOUND IN basement membrane (inferred); cell-cell junction (inferred); extracellular matrix (inferred) | NW_004936598 | 4204094 | 4210492 | Squirrel | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18757873 | AMTN | amelotin | INVOLVED IN amelogenesis (ortholog); enamel mineralization (ortholog); odontogenesis of dentin-containing tooth (ortholog); ASSOCIATED WITH amelogenesis imperfecta type 3A (ortholog); amelogenesis imperfecta type 3B (ortholog); FOUND IN basement membrane (ortholog); cell-cell junction (ortholog); ex tracellular matrix (ortholog) | | | | Green Monkey | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13861230 | AMTN | amelotin | INVOLVED IN amelogenesis (ortholog); enamel mineralization (ortholog); ASSOCIATED WITH amelogenesis imperfecta type 3A (ortholog); amelogenesis imperfecta type 3B (ortholog); FOUND IN basement membrane (inferred); cell-cell junction (inferred); extracellular matrix (inferred) | | | | Pig | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 152177953 | AMTN | amelotin | | | | | Naked Mole-Rat | | symbol | gene, protein-coding |
| 18932393 | Amtn | amelotin | ENCODES a protein that exhibits nucleic acid binding (inferred); INVOLVED IN amelogenesis (ortholog); enamel mineralization (ortholog); positive regulation of biomineral tissue development (ortholog); ASSOCIATED WITH amelogenesis imperfecta type 3A (ortholog); amelogenesis imperfecta type 3B (orthol og); FOUND IN basement membrane (ortholog); cell-cell junction (ortholog); extracellular matrix (ortholog) | | | | Naked Mole-Rat | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625835821 | Amtn | amelotin | INVOLVED IN amelogenesis (ortholog); enamel mineralization (ortholog); odontogenesis of dentin-containing tooth (ortholog); ASSOCIATED WITH amelogenesis imperfecta type 3A (ortholog); amelogenesis imperfecta type 3B (ortholog); FOUND IN basement membrane (ortholog); cell-cell junction (ortholog); ex tracellular matrix (ortholog) | | | | Black Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |