| 1312049 | Akt1s1 | AKT1 substrate 1 | ENCODES a protein that exhibits protein kinase inhibitor activity (ortholog); protein serine/threonine kinase inhibitor activity (ortholog); INVOLVED IN negative regulation of cell size (ortholog); negative regulation of protein kinase activity (ortholog); negative regulation of TOR signaling (ortho log); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Reperfusion Injury (ortholog); Spinal Cord Injuries (ortholog); FOUND IN protein-containing complex; cytosol (ortholog); TORC1 complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 1 | 104469823 | 104476168 | Rat | 144 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1323832 | AKT1S1 | AKT1 substrate 1 | AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM, Mar 2008] | 19 | 49869033 | 49878356 | Human | 155 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1323833 | Akt1s1 | AKT1 substrate 1 | Predicted to enable protein serine/threonine kinase inhibitor activity. Involved in regulation of neuron apoptotic process. Located in cytosol. Is expressed in brain. Orthologous to human AKT1S1 (AKT1 substrate 1). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 44498648 | 44504845 | Mouse | 168 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9061175 | Akt1s1 | AKT1 substrate 1 | ENCODES a protein that exhibits protein kinase inhibitor activity (ortholog); protein serine/threonine kinase inhibitor activity (ortholog); INVOLVED IN negative regulation of cell size (ortholog); negative regulation of protein kinase activity (ortholog); negative regulation of TOR signaling (ortho log); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Reperfusion Injury (ortholog); Spinal Cord Injuries (ortholog); FOUND IN cytosol (ortholog); protein-containing complex (ortholog); TORC1 complex (ortholog) | NW_004955559 | 1055998 | 1063192 | Chinchilla | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12046982 | AKT1S1 | AKT1 substrate 1 | ENCODES a protein that exhibits protein kinase inhibitor activity (inferred); protein serine/threonine kinase inhibitor activity (inferred); INVOLVED IN negative regulation of protein kinase activity (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Reperfusion Injury (ortholog); S pinal Cord Injuries (ortholog); FOUND IN protein-containing complex (ortholog) | 19 | 46882073 | 46890404 | Bonobo | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12130541 | AKT1S1 | AKT1 substrate 1 | ENCODES a protein that exhibits protein kinase inhibitor activity (inferred); protein serine/threonine kinase inhibitor activity (inferred); INVOLVED IN negative regulation of protein kinase activity (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Reperfusion Injury (ortholog); S pinal Cord Injuries (ortholog); FOUND IN protein-containing complex (ortholog) | 1 | 106686349 | 106694854 | Dog | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12719551 | Akt1s1 | AKT1 substrate 1 | ENCODES a protein that exhibits protein kinase inhibitor activity (inferred); protein serine/threonine kinase inhibitor activity (inferred); INVOLVED IN negative regulation of protein kinase activity (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Reperfusion Injury (ortholog); S pinal Cord Injuries (ortholog); FOUND IN protein-containing complex (ortholog) | NW_004936664 | 3657170 | 3664375 | Squirrel | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14021896 | AKT1S1 | AKT1 substrate 1 | ENCODES a protein that exhibits protein kinase inhibitor activity (inferred); protein serine/threonine kinase inhibitor activity (inferred); INVOLVED IN negative regulation of protein kinase activity (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Reperfusion Injury (ortholog); S pinal Cord Injuries (ortholog); FOUND IN protein-containing complex (ortholog) | | | | Pig | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155239412 | akt1s1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18742220 | AKT1S1 | AKT1 substrate 1 | ENCODES a protein that exhibits protein kinase inhibitor activity (inferred); protein serine/threonine kinase inhibitor activity (inferred); INVOLVED IN negative regulation of protein kinase activity (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Reperfusion Injury (ortholog); S pinal Cord Injuries (ortholog); FOUND IN protein-containing complex (ortholog) | | | | Green Monkey | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18906957 | Akt1s1 | AKT1 substrate 1 | ENCODES a protein that exhibits protein kinase inhibitor activity (ortholog); protein serine/threonine kinase inhibitor activity (ortholog); INVOLVED IN negative regulation of cell size (ortholog); negative regulation of protein kinase activity (ortholog); negative regulation of TORC1 signaling (ort holog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Reperfusion Injury (ortholog); Spinal Cord Injuries (ortholog); FOUND IN cytosol (ortholog); protein-containing complex (ortholog); TORC1 complex (ortholog) | | | | Naked Mole-Rat | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626045798 | Akt1s1 | AKT1 substrate 1 | ENCODES a protein that exhibits protein kinase inhibitor activity (ortholog); protein serine/threonine kinase inhibitor activity (ortholog); INVOLVED IN negative regulation of cell size (ortholog); negative regulation of protein kinase activity (ortholog); negative regulation of TOR signaling (ortho log); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Reperfusion Injury (ortholog); Spinal Cord Injuries (ortholog); FOUND IN cytosol (ortholog); protein-containing complex (ortholog); TORC1 complex (ortholog) | | | | Black Rat | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155259901 | akt1s1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155239413 | akt1s1.S | | | | | | African Clawed Frog | | symbol | gene, null |