| 2038 | Adcyap1r1 | ADCYAP receptor type I | ENCODES a protein that exhibits adenylate cyclase binding; small GTPase binding; pituitary adenylate cyclase-activating polypeptide receptor activity (ortholog); INVOLVED IN cAMP biosynthetic process; cAMP metabolic process; development of primary female sexual characteristics; ASSOCIATED WITH cysti tis; Reperfusion Injury; asthma (ortholog); FOUND IN bicellular tight junction; caveola; cell surface; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; acetamide | 4 | 85924171 | 85972973 | Rat | 141 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 10085 | Adcyap1r1 | adenylate cyclase activating polypeptide 1 receptor 1 | Predicted to enable several functions, including G protein-coupled receptor activity; enzyme binding activity; and neuropeptide binding activity. Predicted to be involved in several processes, including cAMP-mediated signaling; positive regulation of inositol phosphate biosynthetic process; and posi tive regulation of intracellular signal transduction. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in several cellular components, including bicellular tight junction; caveola; and cell surface. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including adrenal gland; alimentary system; genitourinary system; immune system; and nervous system. Orthologous to human ADCYAP1R1 (ADCYAP receptor type I). [provided by Alliance of Genome Resources, Apr 2025] | 6 | 55428486 | 55478440 | Mouse | 169 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 736792 | ADCYAP1R1 | ADCYAP receptor type I | This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 an d is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010] | 7 | 31052308 | 31111474 | Human | 151 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 9040653 | Adcyap1r1 | ADCYAP receptor type I | ENCODES a protein that exhibits adenylate cyclase binding (ortholog); pituitary adenylate cyclase-activating polypeptide receptor activity (ortholog); small GTPase binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); cAMP biosynthetic process (ortholog); cAMP metabolic process (ortholog); ASSOCIATED WITH asthma (ortholog); cystitis (ortholog); Reperfusion Injury (ortholog); FOUND IN bicellular tight junction (ortholog); caveola (ortholog); cell surface (ortholog) | NW_004955410 | 32176683 | 32229187 | Chinchilla | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11794541 | ADCYAP1R1 | ADCYAP receptor type I | ENCODES a protein that exhibits adenylate cyclase binding (ortholog); small GTPase binding (ortholog); INVOLVED IN cAMP biosynthetic process (ortholog); cAMP metabolic process (ortholog); development of primary female sexual characteristics (ortholog); ASSOCIATED WITH asthma (ortholog); cystitis (or tholog); Reperfusion Injury (ortholog); FOUND IN bicellular tight junction (ortholog); caveola (ortholog); cell surface (ortholog) | 7 | 31597251 | 31724299 | Bonobo | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12270529 | ADCYAP1R1 | ADCYAP receptor type I | ENCODES a protein that exhibits adenylate cyclase binding (ortholog); small GTPase binding (ortholog); INVOLVED IN cAMP biosynthetic process (ortholog); cAMP metabolic process (ortholog); development of primary female sexual characteristics (ortholog); ASSOCIATED WITH asthma (ortholog); cystitis (or tholog); Reperfusion Injury (ortholog); FOUND IN bicellular tight junction (ortholog); caveola (ortholog); cell surface (ortholog) | 14 | 43707683 | 43761166 | Dog | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12447404 | Adcyap1r1 | ADCYAP receptor type I | ENCODES a protein that exhibits adenylate cyclase binding (ortholog); small GTPase binding (ortholog); INVOLVED IN cAMP biosynthetic process (ortholog); cAMP metabolic process (ortholog); development of primary female sexual characteristics (ortholog); ASSOCIATED WITH asthma (ortholog); cystitis (or tholog); Reperfusion Injury (ortholog); FOUND IN bicellular tight junction (ortholog); caveola (ortholog); cell surface (ortholog) | NW_004936478 | 7278081 | 7322970 | Squirrel | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18491596 | ADCYAP1R1 | ADCYAP receptor type I | ENCODES a protein that exhibits adenylate cyclase binding (ortholog); small GTPase binding (ortholog); INVOLVED IN cAMP biosynthetic process (ortholog); cAMP metabolic process (ortholog); development of primary female sexual characteristics (ortholog); ASSOCIATED WITH asthma (ortholog); cystitis (or tholog); Reperfusion Injury (ortholog); FOUND IN bicellular tight junction (ortholog); caveola (ortholog); cell surface (ortholog) | | | | Green Monkey | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18899618 | Adcyap1r1 | ADCYAP receptor type I | ENCODES a protein that exhibits adenylate cyclase binding (ortholog); pituitary adenylate cyclase-activating polypeptide receptor activity (ortholog); small GTPase binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); cAMP biosynthetic process (ortholog); cAMP metabolic process (ortholog); ASSOCIATED WITH asthma (ortholog); cystitis (ortholog); Reperfusion Injury (ortholog); FOUND IN bicellular tight junction (ortholog); caveola (ortholog); cell surface (ortholog) | | | | Naked Mole-Rat | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625890175 | Adcyap1r1 | ADCYAP receptor type I | ENCODES a protein that exhibits adenylate cyclase binding (ortholog); pituitary adenylate cyclase-activating polypeptide receptor activity (ortholog); small GTPase binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); cAMP biosynthetic process (ortholog); cAMP metabolic process (ortholog); ASSOCIATED WITH asthma (ortholog); cystitis (ortholog); Reperfusion Injury (ortholog); FOUND IN bicellular tight junction (ortholog); caveola (ortholog); cell surface (ortholog) | | | | Black Rat | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155247223 | adcyap1r1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 13905267 | ADCYAP1R1 | ADCYAP receptor type I | ENCODES a protein that exhibits adenylate cyclase binding (ortholog); small GTPase binding (ortholog); INVOLVED IN cAMP biosynthetic process (ortholog); cAMP metabolic process (ortholog); development of primary female sexual characteristics (ortholog); ASSOCIATED WITH asthma (ortholog); cystitis (or tholog); Reperfusion Injury (ortholog); FOUND IN bicellular tight junction (ortholog); caveola (ortholog); cell surface (ortholog); INTERACTS WITH (S)-nicotine; carbon dioxide; dioxygen | | | | Pig | 49 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 155259219 | adcyap1r1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155233973 | adcyap1r1.S | | | | | | African Clawed Frog | | symbol | gene, null |