| 708450 | Adcy10 | adenylate cyclase 10 | ENCODES a protein that exhibits adenylate cyclase activity; ATPase binding; manganese ion binding; INVOLVED IN cAMP biosynthetic process; glucose catabolic process; mitochondrial ATP transmembrane transport; PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH Optic Nerve Injuries; Cardiomegaly (ortholog); Hypercalciuria, Absorptive, 2 (ortholog); FOUND IN apical part of cell; astrocyte end-foot; axon; INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate | 13 | 80280595 | 80366939 | Rat | 183 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 737484 | ADCY10 | adenylate cyclase 10 | The protein encoded by this gene belongs to a distinct class of adenylyl cyclases that is soluble and insensitive to G protein or forskolin regulation. Activity of this protein is regulated by bicarbonate. Variation at this gene has been observed in patients with absorptive hypercalciuria. Alternati vely spliced transcript variants encoding different isoforms have been observed. There is a pseudogene of this gene on chromosome 6. [provided by RefSeq, Jul 2014] | 1 | 167809386 | 167914134 | Human | 221 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 737485 | Adcy10 | adenylate cyclase 10 | Predicted to enable several functions, including ATPase binding activity; bicarbonate binding activity; and manganese ion binding activity. Predicted to be involved in several processes, including plasma membrane bounded cell projection organization; positive regulation of apoptotic process; and pos itive regulation of metabolic process. Located in apical plasma membrane. Is expressed in several structures, including gonad; heart; hemolymphoid system gland; liver; and lung. Orthologous to human ADCY10 (adenylate cyclase 10). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 165309114 | 165404347 | Mouse | 227 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8699973 | Adcy10 | adenylate cyclase 10 | ENCODES a protein that exhibits adenylate cyclase activity (ortholog); ATPase binding (ortholog); bicarbonate binding (ortholog); INVOLVED IN cAMP biosynthetic process (ortholog); epithelial cilium movement involved in extracellular fluid movement (ortholog); glucose catabolic process (ortholog); PA RTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH Cardiomegaly (ortholog); Hypercalciuria, Absorptive, 2 (ortholog); Optic Nerve Injuries (ortholog); FOUND IN apical part of cell (ortholog); apical plasma membrane (ortholog); astrocyte end-foot (ortholog) | NW_004955462 | 9196984 | 9278850 | Chinchilla | 79 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12047418 | ADCY10 | adenylate cyclase 10 | ENCODES a protein that exhibits adenylate cyclase activity (ortholog); ATPase binding (ortholog); manganese ion binding (ortholog); INVOLVED IN cAMP biosynthetic process (ortholog); glucose catabolic process (ortholog); mitochondrial ATP transmembrane transport (ortholog); PARTICIPATES IN adenine ph oshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH Cardiomegaly (ortholog); Hypercalciuria, Absorptive, 2 (ortholog); Optic Nerve Injuries (ortholog); FOUND IN apical part of cell (ortholog); apical plasma membrane (ortholog); astrocyte end-foot (ortholog) | 1 | 143239576 | 143404038 | Bonobo | 101 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12177118 | ADCY10 | adenylate cyclase 10 | ENCODES a protein that exhibits adenylate cyclase activity (ortholog); ATPase binding (ortholog); manganese ion binding (ortholog); INVOLVED IN cAMP biosynthetic process (ortholog); glucose catabolic process (ortholog); mitochondrial ATP transmembrane transport (ortholog); PARTICIPATES IN adenine ph oshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH Cardiomegaly (ortholog); Hypercalciuria, Absorptive, 2 (ortholog); Optic Nerve Injuries (ortholog); FOUND IN apical part of cell (ortholog); apical plasma membrane (ortholog); astrocyte end-foot (ortholog) | 7 | 30576445 | 30660926 | Dog | 96 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12639488 | Adcy10 | adenylate cyclase 10 | ENCODES a protein that exhibits adenylate cyclase activity (ortholog); ATPase binding (ortholog); manganese ion binding (ortholog); INVOLVED IN cAMP biosynthetic process (ortholog); glucose catabolic process (ortholog); mitochondrial ATP transmembrane transport (ortholog); PARTICIPATES IN adenine ph oshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH Cardiomegaly (ortholog); Hypercalciuria, Absorptive, 2 (ortholog); Optic Nerve Injuries (ortholog); FOUND IN apical part of cell (ortholog); apical plasma membrane (ortholog); astrocyte end-foot (ortholog) | NW_004936481 | 18274158 | 18330136 | Squirrel | 96 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14041807 | ADCY10 | adenylate cyclase 10 | ENCODES a protein that exhibits adenylate cyclase activity (ortholog); ATPase binding (ortholog); manganese ion binding (ortholog); INVOLVED IN cAMP biosynthetic process (ortholog); glucose catabolic process (ortholog); mitochondrial ATP transmembrane transport (ortholog); PARTICIPATES IN adenine ph oshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH Cardiomegaly (ortholog); Hypercalciuria, Absorptive, 2 (ortholog); Optic Nerve Injuries (ortholog); FOUND IN apical part of cell (ortholog); apical plasma membrane (ortholog); astrocyte end-foot (ortholog) | | | | Pig | 96 | symbol | gene, protein-coding, INFERRED [RefSeq] |
| 18900110 | Adcy10 | adenylate cyclase 10 | ENCODES a protein that exhibits adenylate cyclase activity (ortholog); ATPase binding (ortholog); bicarbonate binding (ortholog); INVOLVED IN cAMP biosynthetic process (ortholog); epithelial cilium movement involved in extracellular fluid movement (ortholog); glucose catabolic process (ortholog); PA RTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH Cardiomegaly (ortholog); Hypercalciuria, Absorptive, 2 (ortholog); Optic Nerve Injuries (ortholog); FOUND IN apical part of cell (ortholog); apical plasma membrane (ortholog); astrocyte end-foot (ortholog) | | | | Naked Mole-Rat | 91 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18348507 | ADCY10 | adenylate cyclase 10 | ENCODES a protein that exhibits adenylate cyclase activity (ortholog); ATPase binding (ortholog); manganese ion binding (ortholog); INVOLVED IN cAMP biosynthetic process (ortholog); glucose catabolic process (ortholog); mitochondrial ATP transmembrane transport (ortholog); PARTICIPATES IN adenine ph oshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH Cardiomegaly (ortholog); Hypercalciuria, Absorptive, 2 (ortholog); Optic Nerve Injuries (ortholog); FOUND IN apical part of cell (ortholog); apical plasma membrane (ortholog); astrocyte end-foot (ortholog) | | | | Green Monkey | 96 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626076477 | Adcy10 | adenylate cyclase 10 | ENCODES a protein that exhibits adenylate cyclase activity (ortholog); ATPase binding (ortholog); bicarbonate binding (ortholog); INVOLVED IN cAMP biosynthetic process (ortholog); epithelial cilium movement involved in extracellular fluid movement (ortholog); glucose catabolic process (ortholog); PA RTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH Cardiomegaly (ortholog); Hypercalciuria, Absorptive, 2 (ortholog); Optic Nerve Injuries (ortholog); FOUND IN apical part of cell (ortholog); apical plasma membrane (ortholog); astrocyte end-foot (ortholog) | | | | Black Rat | 79 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 2303886 | ADCY10P1 | ADCY10 pseudogene 1 | INTERACTS WITH 4,4'-sulfonyldiphenol; aristolochic acid A; carbon nanotube | 6 | 41101034 | 41140835 | Human | 15 | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, VALIDATED [RefSeq] |