RGD:78738914 Rat Genome Database

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Variant: RGD:78738914 -  Canis lupus familiaris

RGD ID: 78738914
Genic Status: GENIC
Type: SNV (SO:0001483) 
Associated Genes: KPNA5  
Reference Nucleotide: A
Variant Nucleotide: G
Position
Assembly Chr Position
CanFam3.1 1 57,140,893
JBrowse: View Region in Genome Browser (JBrowse)
Model
Breeds: Chinese indigenous dogs




Gene Symbol:KPNA5
Accession:XM_022419358
Location:EXON
Amino Acid Prediction: Q to R (nonsynonymous)
Amino Acid Position: 288
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
probably damaging alignment     -1.489 -2.993 +1.504 109 15 XP_022275066 3tj3 +
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPRNDESMLESPIQDPDISSTVPIPEEEV
ITTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHT
KVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRG
KNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIRAVIDSGVCRRLVELLMHNDYKVVSPALRAVGN
IVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAW
AITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIE
FLQSHENQEIYQKAFDLIEHYFGVEEDDPSIVPQVDESQQQFVFQQQEAPMEGFQL*

Gene Symbol:KPNA5
Accession:XM_541211
Location:EXON
Amino Acid Prediction: Q to R (nonsynonymous)
Amino Acid Position: 291
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
probably damaging alignment     -1.489 -2.993 +1.504 109 15 XP_541211 3tj3 +
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MDAMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPRNDESMLESPIQDPDISSTVPIPE
EEVITTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTF
LHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNL
CRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIRAVIDSGVCRRLVELLMHNDYKVVSPALRA
VGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKE
AAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLD
KIEFLQSHENQEIYQKAFDLIEHYFGVEEDDPSIVPQVDESQQQFVFQQQEAPMEGFQL*
Chinese indigenous dogs (LJ5)