RGD:133636066 Rat Genome Database

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Variant: RGD:133636066 -  Rattus norvegicus

RGD ID: 133636066
Genic Status: GENIC
Type: SNV (SO:0001483) 
Associated Genes: Tp53  
Reference Nucleotide: G
Variant Nucleotide: A
Position
Assembly Chr Position
Rnor_6.0 10 56,196,138
JBrowse: View Region in Genome Browser (JBrowse)
Model




Gene Symbol:Tp53
Accession:NM_030989
Location:EXON
Amino Acid Prediction: R to H (nonsynonymous)
Amino Acid Position: 280
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
benign structure 1.1.1 NO -1.700 -2.366 +0.666 59 6 NP_112251 2p52 +
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MEDSQSDMSIELPLSQETFSCLWKLLPPDDILPTTATGSPNSMEDLFLPQDVAELLEGPEEALQVSAPAAQEPGTEAPAP
VAPASATPWPLSSSVPSQKTYQGNYGFHLGFLQSGTAKSVMCTYSISLNKLFCQLAKTCPVQLWVTSTPPPGTRVRAMAI
YKKSQHMTEVVRRCPHHERCSDGDGLAPPQHLIRVEGNPYAEYLDDRQTFRHSVVVPYEPPEVGSDYTTIHYKYMCNSSC
MGGMNRRPILTIITLEDSSGNLLGRDSFEVRVCACPGRDHRTEEENFRKKEEHCPELPPGSAKRALPTSTSSSPQQKKKP
LDGEYFTLKIRGRERFEMFRELNEALELKDARAAEESGDSRAHSSYPKTKKGQSTSRHKKPMIKKVGPDSD*

Gene Symbol:Tp53
Accession:XM_008767773
Location:EXON
Amino Acid Prediction: R to H (nonsynonymous)
Amino Acid Position: 280
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
probably damaging alignment     -1.176 -4.409 +3.233 224 6 XP_008765995 2p52 +
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MEDSQSDMSIELPLSQETFSCLWKLLPPDDILPTTATGSPNSMEDLFLPQDVAELLEGPEEALQVSAPAAQEPGTEAPAP
VAPASATPWPLSSSVPSQKTYQGNYGFHLGFLQSGTAKSVMCTYSISLNKLFCQLAKTCPVQLWVTSTPPPGTRVRAMAI
YKKSQHMTEVVRRCPHHERCSDGDGLAPPQHLIRVEGNPYAEYLDDRQTFRHSVVVPYEPPEVGSDYTTIHYKYMCNSSC
MGGMNRRPILTIITLEDSSGNLLGRDSFEVRVCACPGRDHRTEEENFRKKEEHCPELPPGSAKRALPTSTSSSPQQKKKP
LDGEYFTLKIRGRERFEMFRELNEALELKDARAAEESGDSRAHSSLQPRTFQALIKKESPNC*

Gene Symbol:Tp53
Accession:XM_017597018
Location:EXON
Amino Acid Prediction: R to H (nonsynonymous)
Amino Acid Position: 280
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
probably damaging alignment     -1.176 -4.409 +3.233 224 6 XP_017452507 2p52 +
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MEDSQSDMSIELPLSQETFSCLWKLLPPDDILPTTATGSPNSMEDLFLPQDVAELLEGPEEALQVSAPAAQEPGTEAPAP
VAPASATPWPLSSSVPSQKTYQGNYGFHLGFLQSGTAKSVMCTYSISLNKLFCQLAKTCPVQLWVTSTPPPGTRVRAMAI
YKKSQHMTEVVRRCPHHERCSDGDGLAPPQHLIRVEGNPYAEYLDDRQTFRHSVVVPYEPPEVGSDYTTIHYKYMCNSSC
MGGMNRRPILTIITLEDSSGNLLGRDSFEVRVCACPGRDHRTEEENFRKKEEHCPELPPGSAKRALPTSTSSSPQQKKKP
LDGEYFTLKIRGRERFEMFRELNEALELKDARAAEESGDSRAHSSLQPRTFQALIKKESPNC*
HXB31/IpcvMcwi (2019)