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Strain Registration

Strain: SS/HsdMcwiCrl

Symbol: SS/HsdMcwiCrl
Strain: SS
Substrain: HsdMcwiCrl
RGD ID: 2308886
Citation ID: RRID:RGD_2308886
Ontology ID: RS:0002215
Also Known As: SS/JrHsdMcwiCrl
Type: inbred
Available Source: Charles River Laboratories
Origination: Charles River Laboratories
Description: Inbred from a congenic control group of Dahl/SS rats (SS/JrHsd) obtained from Dr. Theodore Kurtz (UCSF, CA) which were originally derived from the Harlan SS/Jr colony. Maintained at the Medical College of Wisconsin since 1991, this strain has undergone considerable marker-selected breeding to eliminate residual heterozygosity and genetic contamination. To confirm homozygosity, the strain was tested with 200 microsatellite markers (genome-wide scan at 20cM) all of which were homozygous for all regions tested. (Cowley et al. 2000, Physiol. Genomics 2:107-115). To Charles River in 2001.
Coat Color: Albino
Last Known Status: Unknown






  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SS/HsdMcwiCrlRatToxemia inducesIAGPtoxin40924657associated with anthrax diseaseRGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SS/HsdMcwiCrlRatdecreased susceptibility to induced morbidity/mortality inducedIAGParterial catheter implantation and controlled hemorrhage2302114compared to treated FHH/EurMcwiCrlRGD 

Related Phenotype Data for Term "SS/HsdMcwiCrl" (RS:0002215)

Rat Strains:
Clinical Measurements:
Experimental Conditions:
Measurement Methods:

#
Reference Title
Reference Citation
1. Is survival time after hemorrhage a heritable, quantitative trait?: an initial assessment. Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53.
2. Susceptibility to anthrax lethal toxin-induced rat death is controlled by a single chromosome 10 locus that includes rNlrp1. Newman ZL, etal., PLoS Pathog. 2010 May 20;6(5):e1000906. doi: 10.1371/journal.ppat.1000906.
3. Strains registered by Charles River Laboratories International, Inc. Personal communication with Charles River Laboratories
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines


AssemblySample 
mRatBN7.2 SS/HsdMcwiCrl (2021) View Damaging Variants