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Strain Registration

Strain: SS/HsdMcwiCrl

Symbol: SS/HsdMcwiCrl
Strain: SS
Substrain: HsdMcwiCrl
RGD ID: 2308886
Citation ID: RRID:RGD_2308886
Ontology ID: RS:0002215
Also Known As: SS/JrHsdMcwiCrl
Type: inbred
Available Source: Charles River Laboratories
Origination: Charles River Laboratories
Description: Inbred from a congenic control group of Dahl/SS rats (SS/JrHsd) obtained from Dr. Theodore Kurtz (UCSF, CA) which were originally derived from the Harlan SS/Jr colony. Maintained at the Medical College of Wisconsin since 1991, this strain has undergone considerable marker-selected breeding to eliminate residual heterozygosity and genetic contamination. To confirm homozygosity, the strain was tested with 200 microsatellite markers (genome-wide scan at 20cM) all of which were homozygous for all regions tested. (Cowley et al. 2000, Physiol. Genomics 2:107-115). To Charles River in 2001.
Coat Color: Albino
Last Known Status: Unknown





Disease Annotations     Click to see Annotation Detail View
Toxemia  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table


References

References - curated
# Reference Title Reference Citation
1. Is survival time after hemorrhage a heritable, quantitative trait?: an initial assessment. Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53.
2. Susceptibility to anthrax lethal toxin-induced rat death is controlled by a single chromosome 10 locus that includes rNlrp1. Newman ZL, etal., PLoS Pathog. 2010 May 20;6(5):e1000906. doi: 10.1371/journal.ppat.1000906.
3. Strains registered by Charles River Laboratories International, Inc. Personal communication with Charles River Laboratories
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Strain Samples in RGD with Damaging Variants (Polyphen)
AssemblySample 
mRatBN7.2 SS/HsdMcwiCrl (2021) View Damaging Variants


Additional Information