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Summary
Annotation
RGD Manual Disease
Phenotype
Mammalian Phenotype
Phenotype Values via
References
References - curated
Strain Registration
General
Strain: WAG/RijCmcr
Symbol:
WAG/RijCmcr
Strain:
WAG
Substrain:
RijCmcr
RGD ID:
2303640
Citation ID:
RRID:RGD_2303640
Ontology ID:
RS:0002248
Also Known As:
WAG/RijMCW
Type:
inbred
Available Source:
Not Available
Origination:
Center for Medical Countermeasures Against Radiological Terrorism, Medical College of Wisconsin
Description:
Substrain of WAG/Rij, separated from the Rijswijk colony in about 1975, now maintained at Medical College of Wisconsin
Last Known Status:
Unknown
Annotation
Click to see Annotation Summary View
RGD Manual Disease Annotations
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
WAG/RijCmcr
Rat
pulmonary fibrosis
MODEL: induced
IAGP
2303635
whole thorax irradiation
RGD
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Phenotype Annotations
Click to see Annotation Summary View
Mammalian Phenotype
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
WAG/RijCmcr
Rat
pulmonary interstitial fibrosis
MODEL: induced
IAGP
2303635
whole thorax irradiation
RGD
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Phenotype Values via Phenominer
Click to see Annotation Summary View
Related Phenotype Data for Term "WAG/RijCmcr" (RS:0002248)
Rat Strains:
WAG/RijCmcr
Clinical Measurements:
dose of irradiation that is fatal to 50% of the total study population
dose of whole thorax lung irradiation at which breathing rate increases for 50% of the total study population
percentage of study population developing radiation pneumonitis during a period of time
percentage of study population developing radiation-induced bone marrow disease during a period of time
Experimental Conditions:
leg-out partial body irradiation
partial body irradiation
partial-body irradiation with 5% bone marrow sparing
total body irradiation
whole thorax lung irradiation
Measurement Methods:
probit analysis estimate
Disease Annotations
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pulmonary fibrosis
(IAGP)
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Phenotype Annotations
Click to see Annotation Summary View
Mammalian Phenotype
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pulmonary interstitial fibrosis
(IAGP)
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Phenotype Values via PhenoMiner
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Clinical Measurement
dose of irradiation that is fatal to 50% of the total study population
dose of whole thorax lung irradiation at which breathing rate increases for 50% of the total study population
percentage of study population developing radiation pneumonitis during a period of time
percentage of study population developing radiation-induced bone marrow disease during a period of time
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References
References - curated
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#
Reference Title
Reference Citation
1.
Strain registered by Dr. Moulder
Personal communication between Dr. Moulder and the RGD curators.
2.
RGD Strain RSO annotation pipeline
RGD Automated Pipelines
3.
The WAG/Rij strain: a genetic animal model of absence epilepsy with comorbidity of depression .
Sarkisova K and van Luijtelaar G, Prog Neuropsychopharmacol Biol Psychiatry. 2011 Jun 1;35(4):854-76. doi: 10.1016/j.pnpbp.2010.11.010. Epub 2010 Nov 17.
4.
Arachidonic acid metabolites mediate the radiation-induced increase in glomerular albumin permeability.
Sharma M, etal., Exp Biol Med (Maywood). 2006 Jan;231(1):99-106.
5.
Structural and functional alterations in the rat lung following whole thoracic irradiation with moderate doses: injury and recovery.
Zhang R, etal., Int J Radiat Biol. 2008 Jun;84(6):487-97.
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Region
Additional Information