Strain Report - Rat Genome Database
Welcome
Sign In
Message Center
1 Messages
Go to Message Center
Watched Genes
Watched Ontology Terms
×
Save List to My RGD
Create Name:
Description:
You must be logged in to use this feature
Subscribe to Updates
Select categories you would like to watch. Updates to this gene will be sent to Sign In
Analyze List
×
Gene Annotator (Functional Annotation)
unavailable
Gene Annotator (Annotation Distribution)
unavailable
Variant Visualizer (Genomic Variants)
unavailable
InterViewer (Protein-Protein Interactions)
unavailable
Gviewer (Genome Viewer)
unavailable
Variant Visualizer (Damaging Variants)
unavailable
Gene Annotator (Annotation Comparison)
unavailable
OLGA (Gene List Generator)
unavailable
Excel (Download)
MOET (Multi-Ontology Enrichement)
unavailable
GOLF (Gene-Ortholog Location Finder)
unavailable
x
Send Message
x
Send us a Message
Your email
Message
Send
Submit Data
|
Help
|
Video Tutorials
|
News
|
Publications
|
Download
|
REST API
|
Citing RGD
|
Contact
Home
Search RGD
Grant Resources
Citing RGD
About Us
Contact Us
Data
Genes
Variants
Community Projects
QTLs
Strains
Markers
Genome Information
Ontologies
Cell Lines
References
Download
Submit Data
Analysis & Visualization
OntoMate (Literature Search)
JBrowse (Genome Browser)
Synteny Browser (VCMap)
Variant Visualizer
Multi-Ontology Enrichment (MOET)
Gene-Ortholog Location Finder (GOLF)
InterViewer (Protein-Protein Interactions)
PhenoMiner (Quatitative Phenotypes)
Gene Annotator
OLGA (Gene List Generator)
AllianceMine
GViewer (Genome Viewer)
Diseases
Aging & Age-Related Disease
Cancer & Neoplastic Disease
Cardiovascular Disease
Coronavirus Disease
Developmental Disease
Diabetes
Hematologic Disease
Immune & Inflammatory Disease
Infectious Disease
Liver Disease
Neurological Disease
Obesity & Metabolic Syndrome
Renal Disease
Respiratory Disease
Sensory Organ Disease
Phenotypes & Models
Find Models
Genetic Models
Autism Models
Rat PhenoMiner (Quantitative Phenotypes)
Chinchilla PhenoMiner
Expected Ranges (Quantitative Phenotype)
PhenoMiner Term Comparison
Hybrid Rat Diversity Panel
Phenotypes
Phenotypes in Other Animal Models
Animal Husbandry
Strain Medical Records
Phylogenetics
Strain Availability
Calendar
Rats 101
Submissions
Photo Archive
Pathways
Community
Rat Community Forum
Directory of Rat Laboratories
Video Tutorials
News
RGD Publications
RGD Presentations Archive
Nomenclature Guidelines
Resource Links
Laboratory Resources
Employment Resources
Advanced Search (OLGA)
Summary
Annotation
Phenotype Values via
References
References - curated
Region
Strain Samples in RGD with Damaging Variants
Additional Information
RGD Curation Notes
Nomenclature History
Strain Registration
General
Strain: FXLE12/Stm
Symbol:
FXLE12/Stm
Strain:
FXLE12
Substrain:
Stm
RGD ID:
1302602
Citation ID:
RRID:RGD_1302602
Ontology ID:
RS:0000349
Also Known As:
MDC-02-36; NBRP Rat No: 0124
Type:
recombinant_inbred
Available Source:
National BioResource Project for the Rat in Japan
Origination:
National BioResource Project for the Rat in Japan
Description:
This strain is derived from systematic breeding of the F2 generation between LE/Stm and F344/Stm.
Inbred Generations:
F45
Last Known Status:
Cryopreserved Embryo
Research Usage
Diabetes Obesity; Cancer
Annotation
Click to see Annotation Summary View
Phenotype Values via Phenominer
Click to see Annotation Summary View
Related Phenotype Data for Term "FXLE12/Stm" (RS:0000349)
Rat Strains:
FXLE12/Stm
Clinical Measurements:
activated partial thromboplastin time
blood band neutrophil count to total leukocyte count ratio
blood basophil count to total leukocyte count ratio
blood eosinophil count to total leukocyte count ratio
blood hemoglobin level
blood lymphocyte count to total leukocyte count ratio
blood monocyte count to total leukocyte count ratio
blood segmented neutrophil count to total leukocyte count ratio
body temperature
body weight
both adrenal glands weight to body weight ratio
both adrenal glands wet weight
both kidneys wet weight
both kidneys wet weight as percentage of body weight
both testes wet weight
both testes wet weight to body weight ratio
brain weight to body weight ratio
brain wet weight
heart rate
heart weight to body weight ratio
heart wet weight
hematocrit
liver weight as percentage of body weight
liver wet weight
lung weight to body weight ratio
lung wet weight
mean corpuscular hemoglobin
mean corpuscular hemoglobin concentration
mean corpuscular volume
non-specified leukocyte count to total leukocyte count ratio
plasma alanine aminotransferase activity level
plasma albumin level
plasma albumin to plasma total protein ratio
plasma alkaline phosphatase activity level
plasma aspartate aminotransferase activity level
plasma chloride level
plasma creatinine level
plasma glucose level
plasma high density lipoprotein cholesterol level
plasma low density lipoprotein cholesterol level
plasma phosphate level
plasma potassium level
plasma sodium level
plasma total bilirubin level
plasma total cholesterol level
plasma total protein level
plasma triglyceride level
plasma urea nitrogen level
platelet count
prothrombin time
red blood cell count
spleen weight to body weight ratio
spleen wet weight
systolic blood pressure
timed urine volume
timed urine volume to body weight ratio
total plasma calcium level
urine chloride excretion rate to body weight ratio
urine chloride level
urine potassium excretion rate to body weight ratio
urine potassium level
urine sodium excretion rate to body weight ratio
urine sodium level
white blood cell count
Experimental Conditions:
0.9% sodium chloride solution
fasting
specific pathogen-free condition
Measurement Methods:
automated blood electrolyte analysis
automated cell/particle size/count analysis method
automated coagulometer method
automated differential white blood cell count test
automated plasma albumin analysis
automated plasma analysis
automated plasma creatinine analysis
automated plasma protein analysis
automated plasma total protein analysis
automated urine analysis
digital rectal thermometry
metabolic cage urine volume measurement method
Shimadzu electronic balance post excision weight measurement
tail cuff photoplethysmography
whole body digital scale
Phenotype Values via PhenoMiner
Click to see Annotation Summary View
10
20
30
40
100
All Rows
Options:
View chart
|
Download data table
|
View expanded data table
Clinical Measurement
heart rate
systolic blood pressure
body weight
body temperature
red blood cell count
blood hemoglobin level
white blood cell count
platelet count
hematocrit
mean corpuscular volume
plasma glucose level
plasma aspartate aminotransferase activity level
plasma alanine aminotransferase activity level
plasma alkaline phosphatase activity level
plasma total protein level
plasma albumin level
plasma phosphate level
plasma chloride level
plasma sodium level
plasma potassium level
heart wet weight
heart weight to body weight ratio
both kidneys wet weight
lung wet weight
urine potassium level
urine sodium level
brain weight to body weight ratio
both kidneys wet weight as percentage of body weight
liver weight as percentage of body weight
spleen weight to body weight ratio
brain wet weight
lung weight to body weight ratio
liver wet weight
both adrenal glands wet weight
spleen wet weight
both testes wet weight
activated partial thromboplastin time
prothrombin time
timed urine volume
mean corpuscular hemoglobin
mean corpuscular hemoglobin concentration
blood basophil count to total leukocyte count ratio
blood eosinophil count to total leukocyte count ratio
blood lymphocyte count to total leukocyte count ratio
blood monocyte count to total leukocyte count ratio
total plasma calcium level
urine chloride level
plasma creatinine level
plasma triglyceride level
plasma total cholesterol level
plasma urea nitrogen level
both adrenal glands weight to body weight ratio
plasma high density lipoprotein cholesterol level
plasma low density lipoprotein cholesterol level
both testes wet weight to body weight ratio
urine sodium excretion rate to body weight ratio
timed urine volume to body weight ratio
urine chloride excretion rate to body weight ratio
urine potassium excretion rate to body weight ratio
plasma total bilirubin level
blood segmented neutrophil count to total leukocyte count ratio
blood band neutrophil count to total leukocyte count ratio
non-specified leukocyte count to total leukocyte count ratio
plasma albumin to plasma total protein ratio
10
20
30
40
100
All Rows
References
References - curated
1 to 6 of 6 rows
10
20
30
40
100
All Rows
#
Reference Title
Reference Citation
1.
Propylnitrosourea-induced T-lymphomas in LEXF RI strains of rats: genetic analysis.
Lu LM, etal., Br J Cancer 1999 May;80(5-6):855-61.
2.
Strains registered by the National Bio Resource Project for the Rat in Japan
Personal Communication with NBRP
3.
RGD Strain RSO annotation pipeline
RGD Automated Pipelines
4.
SNP and haplotype mapping for genetic analysis in the rat.
Saar K, etal., Nat Genet. 2008 May;40(5):560-6.
5.
The LEXF: a new set of rat recombinant inbred strains between LE/Stm and F344.
Shisa H, etal., Mamm Genome 1997 May;8(5):324-7.
6.
Evaluation of LEXF/FXLE rat recombinant inbred strains for the genetic dissection of complex traits.
Voigt B, etal., Physiol Genomics. 2007 Nov 27;.
1 to 6 of 6 rows
10
20
30
40
100
All Rows
Region
Strain Samples in RGD with Damaging Variants (Polyphen)
Assembly
Sample
mRatBN7.2
FXLE12/Stm (2019NG)
View Damaging Variants
Additional Information
RGD Curation Notes
Note Type
Note
Reference
strain_reproduction
Good breeding
619600
Nomenclature History
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2012-05-09
FXLE12/Stm
FXLE12/Stm
Name updated
68913
APPROVED