RGD Reference Report - cDNA cloning of a thromboxane A2 receptor from rat astrocytes. - Rat Genome Database

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cDNA cloning of a thromboxane A2 receptor from rat astrocytes.

Authors: Kitanaka, J  Hashimoto, H  Sugimoto, Y  Sawada, M  Negishi, M  Suzumura, A  Marunouchi, T  Ichikawa, A  Baba, A 
Citation: Kitanaka J, etal., Biochim Biophys Acta 1995 Mar 16;1265(2-3):220-3.
RGD ID: 729998
Pubmed: PMID:7696353   (View Abstract at PubMed)

A cDNA clone for rat thromboxane (TX) A2 receptor was obtained from cultured astrocytes. The cDNA encodes a protein of 341 amino acids with seven putative transmembrane domains. The receptor is homologous with mouse and human TXA2 receptors at 92.7% and 71.8%, respectively. Expression of messenger RNA for the receptor was examined by reverse transcriptase-polymerase chain reaction, showing ubiquitous expression in brain glial cells such as astrocytes, oligodendrocytes and microglia.



Gene Tbxa2r thromboxane A2 receptor Rattus norvegicus