RGD Reference Report - "On" and "off" responses of K+-induced synaptosomal proline release: involvement of the sodium pump. - Rat Genome Database

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"On" and "off" responses of K+-induced synaptosomal proline release: involvement of the sodium pump.

Authors: Nickolson, V J 
Citation: Nickolson VJ, J Neurochem. 1982 Jan;38(1):289-92. doi: 10.1111/j.1471-4159.1982.tb10885.x.
RGD ID: 155230706
Pubmed: PMID:6286882   (View Abstract at PubMed)
DOI: DOI:10.1111/j.1471-4159.1982.tb10885.x   (Journal Full-text)

The K+-induced release of the putative neurotransmitter proline in rat cerebral cortex synaptosomes was studied by measuring [5-3H]proline released upon exposure to high-K+ media. In contrast to previous experiments, K+ was not substituted for Na+, which was held constant. Under the resulting conditions of increased osmolarity, two peaks of proline release were obtained, one upon exposure to increased [K+], another upon restoring normal [K+]. The dependence of the latter peak on ionic composition of the medium, and its sensitivity to ouabain are discussed.




Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Notes
Source
Original Reference(s)
Slc6a7Ratprotein catabolic process involved_inEXP PMID:6286882SynGO 

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Notes
Source
Original Reference(s)
Slc6a7Ratsynapse is_active_inEXP PMID:6286882SynGO 


Genes (Rattus norvegicus)
Slc6a7  (solute carrier family 6 member 7)