GWAS1779011_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1779011_H (cholesterol:total lipids ratio, blood VLDL cholesterol amount QTL GWAS1779011 (human)) Homo sapiens

Symbol: GWAS1779011_H
Name: cholesterol:total lipids ratio, blood VLDL cholesterol amount QTL GWAS1779011 (human)
RGD ID: 598059712
Trait: cholesterol:total lipids ratio, blood VLDL cholesterol amount
LOD Score: Not Available
P Value: 3.0E-33
Variance: Not Available
Position No map positions available.
Population Stats: Not Available



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1779011_HHumanblood VLDL cholesterol amount  IAGPrs1077834405850206 GWAS_CATALOGPMID:35213538
GWAS1779011_HHumancholesterol:total lipids ratio  IAGPrs1077834405850206 GWAS_CATALOGPMID:35213538

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs1077834)
Human AssemblyChrPosition (strand)Source
GRCh381558,431,280 - 58,431,281RGD_MAPPER_PIPELINE



1 to 20 of 126 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1779011_H GCST90092917 Cholesterol to total lipids ratio in medium VLDL 115,082 European ancestry individuals T 0.781354 3E-33 32.523 rs1077834 0.0564167 cholesterol:total lipids ratio (EFO:0020943)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1640650_H GCST90479671 mean corpuscular hemoglobin concentration (MCHC, minimum, inv-norm transformed) 114,841 African American or Afro-Caribbean individuals, 55,798 Hispanic or Latin American individuals, 5,943 East Asian ancestry individuals, 407,301 European ancestry individuals T 0.7083 2E-14 13.699 rs1077834 0.02152 mean corpuscular hemoglobin concentration (EFO:0004528)
 PMID:39024449
GWAS1669864_H GCST90475458 mean corpuscular hemoglobin concentration (MCHC, mean, inv-norm transformed) 407,345 European ancestry individuals T 0.7884 3E-27 26.523 rs1077834 0.03458 mean corpuscular hemoglobin concentration (EFO:0004528)
 PMID:39024449
GWAS1672930_H GCST90475462 mean corpuscular hemoglobin concentration (MCHC, minimum, inv-norm transformed) 407,301 European ancestry individuals T 0.7884 5E-20 19.302 rs1077834 0.02901 mean corpuscular hemoglobin concentration (EFO:0004528)
 PMID:39024449
GWAS1738620_H GCST90091677 Postprandial mean diameter of LDL particles null C 0.210896044 5E-11 10.302 rs1077834 0.174207 LDL particle size (OBA:2050113)
 PMID:34610981
GWAS1748377_H GCST90093050 Triglyceride levels in chylomicrons and extremely large VLDL 115,082 European ancestry individuals T 0.781354 1E-33 33 rs1077834 0.0583776 triglyceride measurement (EFO:0004530)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:35213538
GWAS1748721_H GCST90093021 Free cholesterol to total lipids ratio in very large VLDL 114,160 European ancestry individuals T 0.781737 2E-107 106.699 rs1077834 0.106696 free cholesterol:total lipids ratio (EFO:0020945)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1749535_H GCST90093027 Triglycerides to total lipids ratio in very large VLDL 114,160 European ancestry individuals T 0.781737 4E-57 56.398 rs1077834 0.0771698 triglycerides:total lipids ratio (EFO:0020947)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
None Available GCST90093026 Triglyceride levels in very large VLDL 115,082 European ancestry individuals T 0.781354 2E-14 13.699 rs1077834 0.0364797 triglyceride measurement (EFO:0004530)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1755057_H GCST90302163 Total cholesterol to total lipids ratio in chylomicrons and extremely large VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.7609 2E-234 233.699 rs1077834 0.1548 cholesterol:total lipids ratio (EFO:0020943)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:38448586
GWAS1756032_H GCST90302157 Concentration of very small VLDL particles 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.7623 6E-239 238.222 rs1077834 0.1523 blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1756122_H GCST90302167 Free cholesterol to total lipids ratio in chylomicrons and extremely large VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals T 0.7585 2E-112 111.699 rs1077834 0.1108 free cholesterol:total lipids ratio (EFO:0020945)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:38448586
GWAS1756205_H GCST90302062 Free cholesterol to total lipids ratio in medium VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.7626 1E-441 441 rs1077834 0.206 free cholesterol:total lipids ratio (EFO:0020945)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1757292_H GCST90093002 Average diameter for VLDL particles 115,082 European ancestry individuals T 0.781354 9E-169 168.046 rs1077834 0.129064 VLDL particle size (OBA:2050114)
 PMID:35213538
GWAS1757377_H GCST90093019 Cholesteryl esters to total lipids ratio in very large VLDL 114,160 European ancestry individuals T 0.781737 1E-20 20 rs1077834 0.0445994 cholesteryl esters:total lipids ratio (EFO:0020944)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1757478_H GCST90092927 Triglycerides to total lipids ratio in medium VLDL 115,082 European ancestry individuals T 0.781354 3E-52 51.523 rs1077834 0.0717539 triglycerides:total lipids ratio (EFO:0020947)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1758444_H GCST90093046 Total lipid levels in chylomicrons and extremely large VLDL 115,082 European ancestry individuals T 0.781354 7E-17 16.155 rs1077834 0.040217 lipid measurement (EFO:0004529)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:35213538
GWAS1759890_H GCST90302028 Phospholipids to total lipids ratio in large VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals T 0.7582 3E-152 151.523 rs1077834 0.1308 phospholipids:total lipids ratio (EFO:0020946)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1763255_H GCST90245848 Height 5,314,291 European ancestry, Hispanic or Latin American, East Asian ancestry, African ancestry, South Asian ancestry individuals C 0.2646 2E-9 8.699 rs1077834 0.0042 body height (OBA:VT0001253)
 PMID:36224396
GWAS1456551_H GCST003680 C-reactive protein levels or HDL-cholesterol levels (pleiotropy) 65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol) T NR 3E-87 86.523 rs1077834 N/A C-reactive protein measurement (EFO:0004458)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:27286809
1 to 20 of 126 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90092917 GWAS Catalog

Note Type Note Reference