GWAS1756378_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1756378_H (triglycerides:total lipids ratio, blood VLDL cholesterol amount, chylomicron amount QTL GWAS1756378 (human)) Homo sapiens

Symbol: GWAS1756378_H
Name: triglycerides:total lipids ratio, blood VLDL cholesterol amount, chylomicron amount QTL GWAS1756378 (human)
RGD ID: 598037079
Trait: triglycerides:total lipids ratio, blood VLDL cholesterol amount, chylomicron amount
LOD Score: Not Available
P Value: 1E-224
Variance: Not Available
Position No map positions available.
Population Stats: Not Available



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1756378_HHumanblood VLDL cholesterol amount  IAGPrs261334405850206 GWAS_CATALOGPMID:38448586
GWAS1756378_HHumanchylomicron amount  IAGPrs261334405850206 GWAS_CATALOGPMID:38448586
GWAS1756378_HHumantriglycerides:total lipids ratio  IAGPrs261334405850206 GWAS_CATALOGPMID:38448586

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs261334)
Human AssemblyChrPosition (strand)Source
GRCh381558,434,545 - 58,434,546RGD_MAPPER_PIPELINE



1 to 20 of 88 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1756378_H GCST90302173 Triglycerides to total lipids ratio in chylomicrons and extremely large VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals C 0.7745 1E-224 224 rs261334 0.1594 triglycerides:total lipids ratio (EFO:0020947)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:38448586
GWAS1068968_H GCST000805 HDL cholesterol up to 17,723 European ancestry individuals G 0.20 5E-22 21.302 rs261334 0.03 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:20864672
GWAS1119422_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.358 2E-13 12.699 rs261334 0.104 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:29507422
GWAS1119423_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 3E-118 117.523 rs261334 0.094 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:29507422
GWAS1120458_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.209 6E-97 96.222 rs261334 0.097 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:29507422
GWAS1120459_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.369 2E-10 9.699 rs261334 0.081 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:29507422
GWAS1130967_H GCST010245 LDL cholesterol levels 440,546 European ancestry individuals G 0.212726 9E-18 17.046 rs261334 0.0218856 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32203549
GWAS1158540_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.209 6E-30 29.222 rs261334 0.064 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1158573_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 5E-36 35.302 rs261334 0.062 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1162394_H GCST007142 Triglycerides 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.209 5E-21 20.302 rs261334 0.048 triglyceride measurement (EFO:0004530)
 PMID:29507422
GWAS1162395_H GCST007142 Triglycerides 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.358 0.000008 5.097 rs261334 0.068 triglyceride measurement (EFO:0004530)
 PMID:29507422
GWAS1162396_H GCST007142 Triglycerides 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 6E-28 27.222 rs261334 0.049 triglyceride measurement (EFO:0004530)
 PMID:29507422
GWAS1173930_H GCST008987 HDL cholesterol 3,681 individuals G 0.213 6E-7 6.222 rs261334 0.031 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:26160806
GWAS1725952_H GCST009364 Triglyceride levels x long total sleep time interaction (2df test) at least 2,926 African American long sleepers, 364 Chinese ancestry long sleepers, 112 Asian ancestry long sleepers, at least 7,664 European ancestry long sleepers, 1,038 Hispanic/Latino long sleepers, up to 11,906 African American controls, 1,449 Chinese ancestry controls, 454 Asian ancestry controls, at least 31,986 European ancestry controls, 4,091 Hispanic/Latino controls ? NR 6E-21 20.222 rs261334 0.01895 triglyceride measurement (EFO:0004530)
sleep duration trait (OBA:2040171)
 PMID:31719535
GWAS1188855_H GCST003304 HDL cholesterol 4,383 Mexican ancestry individuals G 0.384 9E-13 12.046 rs261334 0.094 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:26780889
GWAS1209624_H GCST008035 High density lipoprotein cholesterol levels 10,085 African American individuals, 17,751 Hispanic/Latino individuals, 2,378 Asian ancestry individuals, 1,912 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 333 individuals ? NR 6E-18 17.222 rs261334 1.014769 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:31217584
GWAS1214315_H GCST90060250 Phosphatidylethanolamine_34:1_[M-H]1- levels 13,814 British ancestry individuals G NR 1E-16 16 rs261334 0.103767 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
GWAS1214653_H GCST90060274 Phosphatidylethanolamine_36:3_[M-H]1- levels 13,814 British ancestry individuals G NR 9E-28 27.046 rs261334 0.137766 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
GWAS1216759_H GCST90060260 Phosphatidylethanolamine_35:2_[M-H]1- levels 13,814 British ancestry individuals G NR 2E-15 14.699 rs261334 0.0869105 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
GWAS1216980_H GCST90060247 Phosphatidylethanolamine_34:2_[M-H]1- levels 13,814 British ancestry individuals G NR 7E-58 57.155 rs261334 0.224657 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
1 to 20 of 88 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90302173 GWAS Catalog

Note Type Note Reference