GWAS1710294_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1710294_H (aging rate QTL GWAS1710294 (human)) Homo sapiens

Symbol: GWAS1710294_H
Name: aging rate QTL GWAS1710294 (human)
RGD ID: 597990995
Trait: aging rate
LOD Score: Not Available
P Value: 9.0E-13
Variance: Not Available
Position No map positions available.
Population Stats: Not Available



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1710294_HHumanaging rate  IAGPrs12203592405850206 GWAS_CATALOGPMID:28502801

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs12203592)
Human AssemblyChrPosition (strand)Source
GRCh386396,321 - 396,322RGD_MAPPER_PIPELINE



1 to 20 of 172 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1710294_H GCST004574 Skin aging (microtopography measurement) 5,087 individuals G 0.79 9E-13 12.046 rs12203592 0.1295 aging rate (OBA:0005494)
 PMID:28502801
GWAS1699814_H GCST003478 Hair greying 6,357 Latin American individuals ? NR 3E-13 12.523 rs12203592 N/A strand of hair color (OBA:0002313)
 PMID:26926045
GWAS1699826_H GCST003479 Hair color 6,357 Latin American individuals ? NR 1E-13 13 rs12203592 N/A strand of hair color (OBA:0002313)
 PMID:26926045
GWAS1699856_H GCST002906 Skin colour saturation 5,857 European ancestry individuals T 0.0919412668601673 3E-9 8.523 rs12203592 0.010126092 Abnormality of skin pigmentation (HP:0001000)
 PMID:25963972
GWAS1699920_H GCST001940 Non-melanoma skin cancer 6,747 European ancestry individuals T NR 7E-14 13.155 rs12203592 0.21 Abnormality of skin pigmentation (HP:0001000)
 PMID:23548203
GWAS1638109_H GCST90479537 Takes medication for skin cancer? 351 African American or Afro-Caribbean cases, 55,154 African American or Afro-Caribbean controls, 5,688 European ancestry cases, 309,980 European ancestry controls C 0.8592 2E-51 50.699 rs12203592 0.3929 drug use measurement (EFO:0007010)
 PMID:39024449
GWAS1638377_H GCST90479538 Skin cancer 431 African American or Afro-Caribbean cases, 55,074 African American or Afro-Caribbean controls, 55,282 European ancestry cases, 260,386 European ancestry controls, 979 Hispanic or Latin American cases, 28,335 Hispanic or Latin American controls C 0.8629 3E-265 264.523 rs12203592 0.3714 PMID:39024449
GWAS1639361_H GCST90475577 Melanomas of skin, dx or hx (PheCode 172.1) 45,274 European ancestry cases, 389,597 European ancestry controls C 0.8403 2E-298 297.699 rs12203592 0.356 cutaneous melanoma (EFO:0000389)
 PMID:39024449
GWAS1639565_H GCST90475580 Other non-epithelial cancer of skin (PheCode 172.2) 68,143 European ancestry cases, 360,898 European ancestry controls C 0.84 1E-323 323 rs12203592 0.394 skin neoplasm (EFO:0004198)
 PMID:39024449
None Available GCST90475602 Malignant neoplasm, other (PheCode 195.1) 6,441 European ancestry cases, 434,830 European ancestry controls C 0.8397 2E-11 10.699 rs12203592 0.1696 PMID:39024449
GWAS1639698_H GCST90475603 Malignant neoplasm of head, face, and neck (PheCode 195.3) 4,578 European ancestry cases, 442,171 European ancestry controls C 0.8396 5E-18 17.302 rs12203592 0.2561 head and neck malignant neoplasia (EFO:0006859)
 PMID:39024449
None Available GCST90475606 Neoplasm of uncertain behavior (PheCode 199) 18,252 European ancestry cases, 403,292 European ancestry controls C 0.8399 9E-13 12.046 rs12203592 0.1103 PMID:39024449
GWAS1642341_H GCST90475583 Squamous cell carcinoma (PheCode 172.22) 19,217 European ancestry cases, 419,674 European ancestry controls C 0.8402 3E-238 237.523 rs12203592 0.4675 squamous cell carcinoma (EFO:0000707)
 PMID:39024449
GWAS1704817_H GCST011100 Aging traits (healthspan, parental lifespan or longevity) (multivariate analysis) at least 837,415 European ancestry individuals C 0.81 8E-26 25.097 rs12203592 N/A healthspan (EFO:0009762)
parental longevity (EFO:0007796)
life span trait (OBA:VT0005372)
 PMID:32678081
GWAS1642837_H GCST90475585 Neoplasm of uncertain behavior of skin (PheCode 173) 59,327 European ancestry cases, 338,779 European ancestry controls C 0.84 3E-236 235.523 rs12203592 0.2859 skin neoplasm (EFO:0004198)
 PMID:39024449
GWAS1643016_H GCST90475582 Basal cell carcinoma (PheCode 172.21) 31,142 European ancestry cases, 404,406 European ancestry controls C 0.8403 3E-233 232.523 rs12203592 0.3656 basal cell carcinoma (EFO:0004193)
 PMID:39024449
GWAS1643129_H GCST90479570 Biological Father: Cancer, Skin 218 African American or Afro-Caribbean cases, 55,287 African American or Afro-Caribbean controls, 20,871 European ancestry cases, 294,797 European ancestry controls, 632 Hispanic or Latin American cases, 28,682 Hispanic or Latin American controls C 0.8629 4E-29 28.398 rs12203592 0.1659 family history of cancer (EFO:0009640)
 PMID:39024449
GWAS1706064_H GCST90002407 White blood cell count 408,112 British individuals T 0.219941 2E-18 17.699 rs12203592 0.022975089 leukocyte quantity (OBA:VT0000217)
 PMID:32888494
GWAS1644086_H GCST90475574 Skin cancer 2,247 Hispanic or Latin American cases, 56,654 Hispanic or Latin American controls C 0.9111 8E-12 11.097 rs12203592 0.3587 PMID:39024449
GWAS1126062_H GCST008870 Keratinocyte cancer (MTAG) at least 18,538 European ancestry cases, at least 340,302 European ancestry controls T 0.222781 2E-302 301.699 rs12203592 1.45 keratinocyte carcinoma (EFO:0010176)
 PMID:31174203
1 to 20 of 172 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST004574 GWAS Catalog

Note Type Note Reference