GWAS1646741_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1646741_H (diabetic neuropathy QTL GWAS1646741 (human)) Homo sapiens

Symbol: GWAS1646741_H
Name: diabetic neuropathy QTL GWAS1646741 (human)
RGD ID: 597589881
Trait: diabetic neuropathy
LOD Score: Not Available
P Value: 3.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381227,810,469 - 27,810,470RGD_MAPPER_PIPELINEGRCh38
GRCh371227,963,402 - 27,963,403RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1646741_HHumandiabetic autonomic neuropathy  IAGPrs3751236405850206 GWAS_CATALOGPMID:39024449
GWAS1646741_HHumandiabetic neuropathy  IAGPrs3751236405850206 GWAS_CATALOGPMID:39024449
GWAS1646741_HHumandiabetic polyneuropathy  IAGPrs3751236405850206 GWAS_CATALOGPMID:39024449

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1646741_HHumandiabetic neuropathy  IAGPrs3751236405850206 GWAS_CATALOGPMID:39024449

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs3751236)
Human AssemblyChrPosition (strand)Source
GRCh381227,810,469 - 27,810,470RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597088854GWAS1184928_Htype 2 diabetes mellitus QTL GWAS1184928 (human)4e-13type 2 diabetes mellitus122781046927810470Human
597084802GWAS1180876_Htype 2 diabetes mellitus QTL GWAS1180876 (human)7e-21type 2 diabetes mellitus122781046927810470Human
597589881GWAS1646741_Hdiabetic neuropathy QTL GWAS1646741 (human)3e-12diabetic neuropathy122781046927810470Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1646741_H GCST90479883 Type 2 diabetes with neurological manifestations (PheCode 250.24) 16,638 African American or Afro-Caribbean cases, 99,303 African American or Afro-Caribbean controls, 7,320 Hispanic or Latin American cases, 50,236 Hispanic or Latin American controls, 443 East Asian ancestry cases, 6,209 East Asian ancestry controls, 59,205 European ancestry cases, 375,439 European ancestry controls G 0.8312 3E-12 11.523 rs3751236 0.05965 diabetic neuropathy (EFO:1000783)
 PMID:39024449
GWAS1180876_H GCST010118 Type 2 diabetes 77,418 East Asian cases, 356,122 East Asian controls G 0.672 7E-21 20.155 rs3751236 1.07 PMID:32499647
GWAS1184928_H GCST010553 Type 2 diabetes 46,511 Asian ancestry cases, 169,776 Asian ancestry controls G 0.6903 4E-13 12.398 rs3751236 0.0684 PMID:32541925
Database
Acc Id
Source(s)
GWAS Catalog GCST90479883 GWAS Catalog

Note Type Note Reference