GWAS1645242_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1645242_H (diabetic neuropathy QTL GWAS1645242 (human)) Homo sapiens

Symbol: GWAS1645242_H
Name: diabetic neuropathy QTL GWAS1645242 (human)
RGD ID: 597588382
Trait: diabetic neuropathy
LOD Score: Not Available
P Value: 4.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381748,982,960 - 48,982,961RGD_MAPPER_PIPELINEGRCh38
GRCh371747,060,322 - 47,060,323RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1645242_HHumandiabetic autonomic neuropathy  IAGPrs35895680405850206 GWAS_CATALOGPMID:39024449
GWAS1645242_HHumandiabetic neuropathy  IAGPrs35895680405850206 GWAS_CATALOGPMID:39024449
GWAS1645242_HHumandiabetic polyneuropathy  IAGPrs35895680405850206 GWAS_CATALOGPMID:39024449

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1645242_HHumandiabetic neuropathy  IAGPrs35895680405850206 GWAS_CATALOGPMID:39024449

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs35895680)
Human AssemblyChrPosition (strand)Source
GRCh381748,982,960 - 48,982,961RGD_MAPPER_PIPELINE


1 to 10 of 20 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597588382GWAS1645242_Hdiabetic neuropathy QTL GWAS1645242 (human)4e-11diabetic neuropathy174898296048982961Human
597098388GWAS1194462_Hmyocardial infarction QTL GWAS1194462 (human)0.000008myocardial infarction174898296048982961Human
597085365GWAS1181439_Htype 2 diabetes mellitus QTL GWAS1181439 (human)8e-27type 2 diabetes mellitus174898296048982961Human
597581437GWAS1638297_Hhypertension, Antihypertensive use measurement QTL GWAS1638297 (human)9e-16hypertension, Antihypertensive use measurement174898296048982961Human
597322620GWAS1418694_Hhigh density lipoprotein cholesterol measurement QTL GWAS1418694 (human)5e-12high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)174898296048982961Human
597237566GWAS1333640_Hcortical thickness QTL GWAS1333640 (human)4e-16cortical thickness174898296048982961Human
597321843GWAS1417917_Hhigh density lipoprotein cholesterol measurement QTL GWAS1417917 (human)1e-09high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)174898296048982961Human
597592436GWAS1649296_Hhigh density lipoprotein cholesterol measurement QTL GWAS1649296 (human)4e-17high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)174898296048982961Human
597090653GWAS1186727_Htype 2 diabetes mellitus QTL GWAS1186727 (human)1e-28type 2 diabetes mellitus174898296048982961Human
597033787GWAS1129861_Hsystolic blood pressure QTL GWAS1129861 (human)5e-14type 2 diabetes mellitussystolic blood pressure (CMO:0000004)174898296048982961Human

1 to 10 of 20 rows


1 to 20 of 23 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1645242_H GCST90475676 Type 2 diabetes with neurological manifestations (PheCode 250.24) 59,205 European ancestry cases, 375,439 European ancestry controls C 0.6969 4E-11 10.398 rs35895680 0.04459 diabetic neuropathy (EFO:1000783)
 PMID:39024449
GWAS1638297_H GCST90479552 Takes medication for high blood pressure? 35,848 African American or Afro-Caribbean cases, 19,657 African American or Afro-Caribbean controls, 14,901 Hispanic or Latin American cases, 14,413 Hispanic or Latin American controls, 1,884 East Asian ancestry cases, 1,663 East Asian ancestry controls, 179,356 European ancestry cases, 136,312 European ancestry controls C 0.7294 9E-16 15.046 rs35895680 0.0521 hypertension (EFO:0000537)
Antihypertensive use measurement (EFO:0009927)
 PMID:39024449
GWAS1642630_H GCST90492734 Type 2 diabetes 50,251 African American cases, 103,909 African American controls, 88,109 East Asian ancestry cases, 339,395 East Asian ancestry controls, 242,283 European ancestry cases, 1,569,734 European ancestry controls, 29,375 Hispanic cases, 59,368 Hispanic controls, 1,602 South African ancestry cases, 976 South African ancestry controls, 16,832 South Asian ancestry cases, 33,767 South Asian ancestry controls C 0.76604 4E-31 30.398 rs35895680 N/A PMID:38374256
GWAS1129861_H GCST007267 Systolic blood pressure 365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals A 0.3015 5E-14 13.302 rs35895680 0.2251 systolic blood pressure (EFO:0006335)
 PMID:30578418
GWAS1131842_H GCST009379 Type 2 diabetes 74,124 European ancestry cases, 824,006 European ancestry controls C 0.678 3E-15 14.523 rs35895680 1.06 PMID:30297969
GWAS1649296_H GCST90475356 high density lipoprotein cholesterol (HDLC, minimm, inv-norm transformed) 404,121 European ancestry individuals C 0.6978 4E-17 16.398 rs35895680 0.02703 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:39024449
GWAS1154295_H GCST007077 Type 2 diabetes approximately 459,000 European ancestry individuals ? NR 7E-8 7.155 rs35895680 N/A PMID:30595370
GWAS1181439_H GCST010557 Type 2 diabetes 148,726 European ancestry cases, 24,646 African American cases, 8,616 Hispanic cases, 46,511 Asian ancestry cases, 965,732 European ancestry controls, 31,446 African American controls, 11,829 Hispanic controls, 169,776 Asian ancestry controls C 0.7066 8E-27 26.097 rs35895680 0.0499 PMID:32541925
GWAS1186727_H GCST010555 Type 2 diabetes 148,726 European ancestry cases, 965,732 European ancestry controls C 0.6858 1E-28 28 rs35895680 0.0559 PMID:32541925
GWAS1194462_H GCST003117 Myocardial infarction 27,509 European ancestry cases, 130 African American cases, 278 Hispanic American cases, 10,257 South Asian ancestry cases, 288 Lebanese ancestry cases, 1,687 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls C 0.72 0.000008 5.097 rs35895680 1.06 myocardial infarction (EFO:0000612)
 PMID:26343387
GWAS1225269_H GCST90310296 Pulse pressure 1,028,980 European ancestry individuals A NR 5E-8 7.302 rs35895680 0.1033 pulse pressure measurement (EFO:0005763)
 PMID:38689001
GWAS1259153_H GCST90018926 Type 2 diabetes 38,841 European ancestry cases, 451,248 European ancestry controls, 45,383 East Asian ancestry cases, 132,032 East Asian ancestry controls A NR 2E-11 10.699 rs35895680 0.0584 PMID:34594039
GWAS1295447_H GCST90310295 Diastolic blood pressure 1,028,980 European ancestry individuals A NR 2E-8 7.699 rs35895680 0.0926 diastolic blood pressure (EFO:0006336)
 PMID:38689001
GWAS1333640_H GCST90091061 Cortical thickness 35,657 White British ancestry individuals A 0.3287 4E-16 15.398 rs35895680 N/A cortical thickness (EFO:0004840)
 PMID:34560273
None Available GCST90132183 Type 2 diabetes 251,740 European ancestry individuals, 139,705 East Asian ancestry individuals, 40,737 South Asian ancestry individuals, 27,417 Hispanic individuals, 30,167 African American individuals, 2,426 Zulu ancestry individuals C NR 5E-14 13.302 rs35895680 1.05 PMID:35551307
GWAS1694075_H GCST90132184 Type 2 diabetes 251,740 European ancestry individuals C 0.677 1E-15 15 rs35895680 0.055 PMID:35551307
GWAS1762370_H GCST90475229 creatinine (mean, inv-norm transformed) 421,411 European ancestry individuals C 0.6977 3E-11 10.523 rs35895680 0.01838 serum creatinine amount (OBA:2050096)
 PMID:39024449
GWAS1417917_H GCST90239652 High density lipoprotein cholesterol levels 1,320,016 European ancestry individuals A 0.313655 1E-9 9 rs35895680 0.012067 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:34887591
GWAS1418694_H GCST90239649 High density lipoprotein cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 5E-12 11.302 rs35895680 N/A high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:34887591
GWAS1419915_H GCST90131901 Insomnia 593,724 European ancestry cases, 1,771,286 European ancestry controls A NR 2E-9 8.699 rs35895680 0.006 insomnia (EFO:0004698)
 PMID:35835914
1 to 20 of 23 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90475676 GWAS Catalog

Note Type Note Reference