GWAS1645028_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

QTL: GWAS1645028_H (diabetic neuropathy QTL GWAS1645028 (human)) Homo sapiens

Symbol: GWAS1645028_H
Name: diabetic neuropathy QTL GWAS1645028 (human)
RGD ID: 597588168
Trait: diabetic neuropathy
LOD Score: Not Available
P Value: 3.0E-29
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382164,656,581 - 164,656,582RGD_MAPPER_PIPELINEGRCh38
GRCh372165,513,091 - 165,513,092RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1645028_HHumandiabetic autonomic neuropathy  IAGPrs10195252405850206 GWAS_CATALOGPMID:39024449
GWAS1645028_HHumandiabetic neuropathy  IAGPrs10195252405850206 GWAS_CATALOGPMID:39024449
GWAS1645028_HHumandiabetic polyneuropathy  IAGPrs10195252405850206 GWAS_CATALOGPMID:39024449

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1645028_HHumandiabetic neuropathy  IAGPrs10195252405850206 GWAS_CATALOGPMID:39024449

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs10195252)
Human AssemblyChrPosition (strand)Source
GRCh382164,656,581 - 164,656,582RGD_MAPPER_PIPELINE


1 to 10 of 75 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
596963604GWAS1083123_Hfree cholesterol in small VLDL measurement QTL GWAS1083123 (human)1e-13free cholesterol in small VLDL measurement 2164656581164656582Human
597348634GWAS1444708_HBMI-adjusted waist-hip ratio QTL GWAS1444708 (human)2e-31body size trait (VT:0100005)2164656581164656582Human
597388443GWAS1484517_HBMI-adjusted waist circumference QTL GWAS1484517 (human)2e-13body size trait (VT:0100005)diastolic blood pressure (CMO:0000005)2164656581164656582Human
597606556GWAS1663416_Hmetabolic disease QTL GWAS1663416 (human)3e-13metabolic diseasediastolic blood pressure (CMO:0000005)2164656581164656582Human
597368606GWAS1464680_Htype 2 diabetes mellitus QTL GWAS1464680 (human)6e-25type 2 diabetes mellitus2164656581164656582Human
597403798GWAS1499872_HBMI-adjusted waist circumference QTL GWAS1499872 (human)4e-15body size trait (VT:0100005)2164656581164656582Human
597598864GWAS1655724_HHbA1c measurement QTL GWAS1655724 (human)9e-27HbA1c measurementblood hemoglobin A1c level (CMO:0002786)2164656581164656582Human
597385877GWAS1481951_HBMI-adjusted waist-hip ratio, physical activity measurement QTL GWAS1481951 (human)2e-25wellness/fitness trait (VT:1000152)voluntary body movement measurement (CMO:0000954)2164656581164656582Human
597370644GWAS1466718_Hwaist-hip ratio QTL GWAS1466718 (human)2e-24waist-hip ratiowaist to hip ratio (WHR) (CMO:0000020)2164656581164656582Human
597386632GWAS1482706_HBMI-adjusted waist-hip ratio, physical activity measurement QTL GWAS1482706 (human)7e-27wellness/fitness trait (VT:1000152)voluntary body movement measurement (CMO:0000954)2164656581164656582Human

1 to 10 of 75 rows


1 to 20 of 96 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1645028_H GCST90475676 Type 2 diabetes with neurological manifestations (PheCode 250.24) 59,205 European ancestry cases, 375,439 European ancestry controls T 0.5949 3E-29 28.523 rs10195252 0.06562 diabetic neuropathy (EFO:1000783)
PMID:39024449
GWAS1112111_H GCST004501 Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) 97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men T 0.5727 1E-13 13 rs10195252 N/A smoking behavior (EFO:0004318)
BMI-adjusted waist circumference (EFO:0007789)
PMID:28443625
GWAS1112394_H GCST004505 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) 95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men T 0.575 5E-11 10.302 rs10195252 0.0253 smoking behavior (EFO:0004318)
BMI-adjusted waist-hip ratio (EFO:0007788)
PMID:28443625
GWAS1112395_H GCST004505 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) 95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men T 0.575 1E-22 22 rs10195252 0.0518 smoking behavior (EFO:0004318)
BMI-adjusted waist-hip ratio (EFO:0007788)
PMID:28443625
GWAS1112650_H GCST004067 Hip circumference adjusted for BMI up to 56,910 European ancestry men, up to 86,570 European ancestry women T 0.5909 1E-10 10 rs10195252 0.0231 BMI-adjusted hip circumference (EFO:0008039)
PMID:25673412
GWAS1112651_H GCST004067 Hip circumference adjusted for BMI up to 56,910 European ancestry men, up to 86,570 European ancestry women T 0.5909 1E-11 11 rs10195252 0.031 BMI-adjusted hip circumference (EFO:0008039)
PMID:25673412
GWAS1635441_H GCST90475680 Insulin pump user (PheCode 250.3) 11,279 European ancestry cases, 430,909 European ancestry controls T 0.5948 1E-12 12 rs10195252 0.09606 insulin measurement (EFO:0004467)
PMID:39024449
GWAS1637603_H GCST90475689 Diabetic retinopathy (PheCode 250.7) 29,668 European ancestry cases, 402,541 European ancestry controls T 0.5946 2E-21 20.699 rs10195252 0.07682 diabetic retinopathy (EFO:0003770)
PMID:39024449
GWAS1705107_H GCST008033 Fasting blood insulin 5,525 African American individuals, 12,687 Hispanic/Latino individuals, 1,547 Asian ancestry individuals, 1,397 Native Hawaiian ancestry individuals, 395 Native American ancestry individuals ? NR 1E-7 7 rs10195252 0.05932476 blood insulin amount (OBA:VT0001560)
PMID:31217584
GWAS1646810_H GCST90479886 Insulin pump user (PheCode 250.3) 4,132 African American or Afro-Caribbean cases, 114,507 African American or Afro-Caribbean controls, 11,279 European ancestry cases, 430,909 European ancestry controls, 1,835 Hispanic or Latin American cases, 56,635 Hispanic or Latin American controls T 0.542 7E-12 11.155 rs10195252 0.08514 insulin measurement (EFO:0004467)
PMID:39024449
GWAS1649373_H GCST90475353 high density lipoprotein cholesterol (HDLC, minimm, inv-norm transformed) 54,914 Hispanic or Latin American individuals T 0.6938 8E-12 11.097 rs10195252 0.04504 high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:39024449
GWAS1652567_H GCST90475205 High cholesterol 176,604 European ancestry cases, 139,064 European ancestry controls T 0.595 2E-15 14.699 rs10195252 0.03857 Hypercholesterolemia (HP:0003124)
PMID:39024449
GWAS1655489_H GCST90479502 Hemoglobin A1c (HbA1c, minimum, inv-norm transformed) 98,578 African American or Afro-Caribbean individuals, 49,152 Hispanic or Latin American individuals, 5,466 East Asian ancestry individuals, 338,640 European ancestry individuals T 0.5449 3E-21 20.523 rs10195252 0.02978 HbA1c measurement (EFO:0004541)
PMID:39024449
GWAS1655724_H GCST90479501 Hemoglobin A1c (HbA1c, mean, inv-norm transformed) 98,735 African American or Afro-Caribbean individuals, 49,225 Hispanic or Latin American individuals, 5,475 East Asian ancestry individuals, 338,848 European ancestry individuals T 0.5448 9E-27 26.046 rs10195252 0.03466 HbA1c measurement (EFO:0004541)
PMID:39024449
GWAS1656028_H GCST90479500 Hemoglobin A1c (HbA1c, maximum, inv-norm transformed) 98,772 African American or Afro-Caribbean individuals, 49,229 Hispanic or Latin American individuals, 5,477 East Asian ancestry individuals, 338,857 European ancestry individuals T 0.5448 2E-27 26.699 rs10195252 0.03421 HbA1c measurement (EFO:0004541)
PMID:39024449
GWAS1660929_H GCST90476439 triglyceride (minimum, inv-norm transformed) 391,797 European ancestry individuals T 0.5956 2E-45 44.699 rs10195252 0.03954 triglyceride measurement (EFO:0004530)
PMID:39024449
GWAS1662681_H GCST90475094 Hemoglobin A1c (HbA1c, mean, inv-norm transformed) 338,848 European ancestry individuals T 0.5962 2E-54 53.699 rs10195252 0.04513 HbA1c measurement (EFO:0004541)
PMID:39024449
GWAS1663379_H GCST90475097 Hemoglobin A1c (HbA1c, minimum, inv-norm transformed) 338,640 European ancestry individuals T 0.5962 9E-43 42.046 rs10195252 0.03941 HbA1c measurement (EFO:0004541)
PMID:39024449
GWAS1663416_H GCST90479929 Disorders of lipid metabolism (PheCode 272) 82,107 African American or Afro-Caribbean cases, 31,954 African American or Afro-Caribbean controls, 39,984 Hispanic or Latin American cases, 15,849 Hispanic or Latin American controls, 4,488 East Asian ancestry cases, 1,866 East Asian ancestry controls, 335,948 European ancestry cases, 90,622 European ancestry controls T 0.5463 3E-13 12.523 rs10195252 0.03872 metabolic disease (EFO:0000589)
PMID:39024449
GWAS1664585_H GCST90476435 triglyceride (mean, inv-norm transformed) 391,626 European ancestry individuals T 0.5956 1E-65 65 rs10195252 0.04865 triglyceride measurement (EFO:0004530)
PMID:39024449
1 to 20 of 96 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90475676 GWAS Catalog

Note Type Note Reference