GWAS1477662_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1477662_H (platelet count QTL GWAS1477662 (human)) Homo sapiens

Symbol: GWAS1477662_H
Name: platelet count QTL GWAS1477662 (human)
RGD ID: 597381588
Trait: platelet quantity   (VT:0003179)    
Measurement Type: platelet count   (CMO:0000029)    
LOD Score: Not Available
P Value: 2.0E-37
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381951,224,706 - 51,224,707RGD_MAPPER_PIPELINEGRCh38
GRCh371951,727,962 - 51,727,963RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1477662_HHumanplatelet count  IAGPrs3865444405850206 GWAS_CATALOGPMID:32888493

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1477662_HHumanplatelet quantity  IAGPrs3865444405850206 GWAS_CATALOGPMID:32888493

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1477662_HHumanplatelet count  IAGPrs3865444405850206 GWAS_CATALOGPMID:32888493

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
38667249LOC107985327uncharacterized LOC107985327195118690851271167Human
1347694CD33CD33 molecule195121107651240016Human


Peak: (rs3865444)
Human AssemblyChrPosition (strand)Source
GRCh381951,224,706 - 51,224,707RGD_MAPPER_PIPELINE


1 to 10 of 48 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597385819GWAS1481893_Hmonocyte count QTL GWAS1481893 (human)9e-15monocyte count195122470651224707Human
597480989GWAS1577063_Hreticulocyte measurement QTL GWAS1577063 (human)7e-13reticulocyte morphology trait (VT:0002424)red blood cell measurement (CMO:0001356)195122470651224707Human
597464095GWAS1560169_HAlzheimer disease QTL GWAS1560169 (human)0.000007Alzheimer disease195122470651224707Human
597480472GWAS1576546_Hmonocyte count QTL GWAS1576546 (human)3e-14monocyte quantity (VT:0000223)blood monocyte count (CMO:0000032)195122470651224707Human
597603928GWAS1660788_HRed cell distribution width QTL GWAS1660788 (human)5e-21Red cell distribution widthred blood cell distribution width- standard deviation (CMO:0003232)195122470651224707Human
597375581GWAS1471655_Hlymphocyte count QTL GWAS1471655 (human)1e-24lymphocyte countblood lymphocyte count (CMO:0000031)195122470651224707Human
596950812GWAS1070331_HRed cell distribution width QTL GWAS1070331 (human)1e-11Red cell distribution width195122470651224707Human
597370450GWAS1466524_HAlzheimer disease QTL GWAS1466524 (human)2e-09Alzheimer disease195122470651224707Human
407405508GWAS1054484_Hobsolete_red blood cell distribution width QTL GWAS1054484 (human)1e-11obsolete_red blood cell distribution width195122470651224707Human
597483730GWAS1579804_Hlymphocyte count QTL GWAS1579804 (human)8e-16lymphocyte countblood lymphocyte count (CMO:0000031)195122470651224707Human

1 to 10 of 48 rows


1 to 20 of 52 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1477662_H GCST90002361 Platelet count 721,201 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals A 0.290281 2E-37 36.699 rs3865444 N/A platelet count (EFO:0004309)
 PMID:32888493
GWAS1697832_H GCST004610 White blood cell count 172,435 European ancestry individuals A 0.3241 2E-10 9.699 rs3865444 0.02439036 leukocyte quantity (OBA:VT0000217)
 PMID:27863252
GWAS1113880_H GCST90002381 Eosinophil counts 408,112 British individuals A 0.323992 8E-13 12.097 rs3865444 0.01688486 eosinophil count (EFO:0004842)
 PMID:32888494
GWAS1654548_H GCST90479502 Hemoglobin A1c (HbA1c, minimum, inv-norm transformed) 98,578 African American or Afro-Caribbean individuals, 49,152 Hispanic or Latin American individuals, 5,466 East Asian ancestry individuals, 338,640 European ancestry individuals C 0.7236 1E-11 11 rs3865444 0.02381 HbA1c measurement (EFO:0004541)
 PMID:39024449
GWAS1660788_H GCST90476365 red cell diameter width (RDW, minimum, inv-norm transformed) 380,819 European ancestry individuals C 0.6888 5E-21 20.302 rs3865444 0.02661 Red cell distribution width (EFO:0009188)
 PMID:39024449
GWAS1663135_H GCST90475097 Hemoglobin A1c (HbA1c, minimum, inv-norm transformed) 338,640 European ancestry individuals C 0.6888 4E-18 17.398 rs3865444 0.02644 HbA1c measurement (EFO:0004541)
 PMID:39024449
GWAS1663711_H GCST90476361 red cell diameter width (RDW, mean, inv-norm transformed) 380,796 European ancestry individuals C 0.6888 4E-23 22.398 rs3865444 0.02827 Red cell distribution width (EFO:0009188)
 PMID:39024449
GWAS1669829_H GCST90480671 red cell diameter width (RDW, maximum, inv-norm transformed) 110,467 African American or Afro-Caribbean individuals, 51,877 Hispanic or Latin American individuals, 5,548 East Asian ancestry individuals, 380,351 European ancestry individuals C 0.7243 5E-11 10.302 rs3865444 0.01994 Red cell distribution width (EFO:0009188)
 PMID:39024449
GWAS1670369_H GCST90480673 red cell diameter width (RDW, minimum, inv-norm transformed) 110,610 African American or Afro-Caribbean individuals, 51,949 Hispanic or Latin American individuals, 5,548 East Asian ancestry individuals, 380,819 European ancestry individuals C 0.7243 1E-14 14 rs3865444 0.02532 Red cell distribution width (EFO:0009188)
 PMID:39024449
GWAS1671806_H GCST90480650 platelet count (maximum, inv-norm transformed) 114,580 African American or Afro-Caribbean individuals, 55,712 Hispanic or Latin American individuals, 5,942 East Asian ancestry individuals, 406,601 European ancestry individuals C 0.7234 2E-14 13.699 rs3865444 0.0263 platelet count (EFO:0004309)
 PMID:39024449
GWAS1672040_H GCST90480672 red cell diameter width (RDW, mean, inv-norm transformed) 110,558 African American or Afro-Caribbean individuals, 51,938 Hispanic or Latin American individuals, 5,549 East Asian ancestry individuals, 380,796 European ancestry individuals C 0.7243 9E-15 14.046 rs3865444 0.02509 Red cell distribution width (EFO:0009188)
 PMID:39024449
GWAS1673754_H GCST90475458 mean corpuscular hemoglobin concentration (MCHC, mean, inv-norm transformed) 407,345 European ancestry individuals C 0.6889 2E-16 15.699 rs3865444 0.02282 mean corpuscular hemoglobin concentration (EFO:0004528)
 PMID:39024449
GWAS1747234_H GCST90001517 CD33+ HLA DR+ Absolute Count 1,858 Sardinian (founder/genetic isolate) ancestry individuals A 0.21313 4E-21 20.398 rs3865444 0.3696 myeloid leukocyte count (OBA:2045223)
 PMID:32929287
GWAS1747235_H GCST90001518 CD33+ HLA DR+ CD14- Absolute Count 1,858 Sardinian (founder/genetic isolate) ancestry individuals A 0.21313 2E-21 20.699 rs3865444 0.3767 myeloid leukocyte count (OBA:2045223)
 PMID:32929287
GWAS1747244_H GCST90001532 Basophil Absolute Count 1,857 Sardinian (founder/genetic isolate) ancestry individuals A 0.21325 8E-35 34.097 rs3865444 0.4855 myeloid leukocyte count (OBA:2045223)
 PMID:32929287
GWAS1747245_H GCST90001533 Basophil %CD33dim HLA DR- CD66b- 1,857 Sardinian (founder/genetic isolate) ancestry individuals A 0.21325 1E-40 40 rs3865444 0.5183 myeloid leukocyte count (OBA:2045223)
 PMID:32929287
GWAS1747248_H GCST90001520 CD33+ HLA DR+ CD14dim Absolute Count 1,858 Sardinian (founder/genetic isolate) ancestry individuals A 0.21313 1E-16 16 rs3865444 0.3278 myeloid leukocyte count (OBA:2045223)
 PMID:32929287
GWAS1747271_H GCST90001524 Granulocytic Myeloid-Derived Suppressor Cells Absolute Count 1,856 Sardinian (founder/genetic isolate) ancestry individuals A 0.21282 1E-12 12 rs3865444 0.2687 myeloid leukocyte count (OBA:2045223)
 PMID:32929287
GWAS1747771_H GCST90480725 white blood cell count (WBC, minimum, inv-norm transformed) 108,942 African American or Afro-Caribbean individuals, 49,991 Hispanic or Latin American individuals, 5,838 East Asian ancestry individuals, 381,267 European ancestry individuals C 0.7252 6E-23 22.222 rs3865444 0.03263 leukocyte quantity (OBA:VT0000217)
 PMID:39024449
GWAS1747994_H GCST90480724 white blood cell count (WBC, mean, inv-norm transformed) 108,896 African American or Afro-Caribbean individuals, 49,978 Hispanic or Latin American individuals, 5,839 East Asian ancestry individuals, 381,099 European ancestry individuals C 0.7252 3E-26 25.523 rs3865444 0.03685 leukocyte quantity (OBA:VT0000217)
 PMID:39024449
1 to 20 of 52 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90002361 GWAS Catalog

Note Type Note Reference