GWAS1424951_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1424951_H (osteoarthritis QTL GWAS1424951 (human)) Homo sapiens

Symbol: GWAS1424951_H
Name: osteoarthritis QTL GWAS1424951 (human)
RGD ID: 597328877
Trait: osteoarthritis
LOD Score: Not Available
P Value: 3.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3841,702,517 - 1,702,518RGD_MAPPER_PIPELINEGRCh38
GRCh3741,704,244 - 1,704,245RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1424951_HHumanosteoarthritis  IAGPrs11732213405850206Based on the MONDO term ID from GWASGWAS_CATALOGPMID:36411363


#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1350910SLBPstem-loop histone mRNA binding protein416927311712319Human


Peak: (rs11732213)
Human AssemblyChrPosition (strand)Source
GRCh3841,702,517 - 1,702,518RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597329179GWAS1425253_Hosteoarthritis QTL GWAS1425253 (human)0.0000005osteoarthritis417025171702518Human
597328604GWAS1424678_Hosteoarthritis QTL GWAS1424678 (human)4e-08osteoarthritis417025171702518Human
597341837GWAS1437911_Hosteoarthritis QTL GWAS1437911 (human)0.000002osteoarthritis417025171702518Human
597328877GWAS1424951_Hosteoarthritis QTL GWAS1424951 (human)3e-09osteoarthritis417025171702518Human
597113789GWAS1209863_Hosteoarthritis, hip, osteoarthritis, knee QTL GWAS1209863 (human)9e-10osteoarthritis, hip, osteoarthritis, knee417025171702518Human
597337185GWAS1433259_Hosteoarthritis QTL GWAS1433259 (human)0.0000002osteoarthritis417025171702518Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1424951_H GCST90134284 Osteoarthritis 140,025 European ancestry cases, 344,349 European ancestry controls, 140,025 South Asian ancestry cases, 344,349 South Asian ancestry controls, 140,025 East Asian ancestry cases, 344,349 East Asian ancestry controls, 140,025 African ancestry cases, 344,349 African ancestry controls, 140,025 Hispanic or Latin American cases, 344,349 Hispanic or Latin American controls T 0.81 3E-9 8.523 rs11732213 1.006 PMID:36411363
GWAS1705243_H GCST010701 Cortical surface area (MOSTest) 26,502 European ancestry individuals ? NR 5E-9 8.302 rs11732213 N/A cerebral cortex area attribute (OBA:2045267)
neuroimaging measurement (EFO:0004346)
 PMID:32665545
GWAS1209863_H GCST007092 Osteoarthritis of the hip or knee 39,427 European ancestry cases, 378,169 European ancestry controls T 0.81 9E-10 9.046 rs11732213 1.06 osteoarthritis, hip (EFO:1000786)
osteoarthritis, knee (EFO:0004616)
 PMID:30664745
GWAS1424678_H GCST90134286 Osteoarthritis 133,506 European ancestry cases, 335,938 European ancestry controls, 133,506 South Asian ancestry cases, 335,938 South Asian ancestry controls, 133,506 East Asian ancestry cases, 335,938 East Asian ancestry controls, 133,506 African ancestry cases, 335,938 African ancestry controls, 133,506 Hispanic or Latin American cases, 335,938 Hispanic or Latin American controls ? NR 4E-8 7.398 rs11732213 1.0367595 PMID:36411363
GWAS1425253_H GCST90134285 Osteoarthritis 58,574 European ancestry cases, 262,785 European ancestry controls, 58,574 South Asian ancestry cases, 262,785 South Asian ancestry controls, 58,574 East Asian ancestry cases, 262,785 East Asian ancestry controls, 58,574 African ancestry cases, 262,785 African ancestry controls ? NR 5E-7 6.302 rs11732213 1.0059607 PMID:36411363
GWAS1433259_H GCST90134288 Osteoarthritis 109,358 European ancestry cases, 303,812 European ancestry controls ? NR 2E-7 6.699 rs11732213 1.0366559 PMID:36411363
GWAS1437911_H GCST90134279 Osteoarthritis 54,039 European ancestry cases, 239,780 European ancestry controls ? NR 0.000002 5.699 rs11732213 0.96 PMID:36411363
Database
Acc Id
Source(s)
GWAS Catalog GCST90134284 GWAS Catalog

Note Type Note Reference