GWAS1247245_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1247245_H (osteoarthritis, hand QTL GWAS1247245 (human)) Homo sapiens

Symbol: GWAS1247245_H
Name: osteoarthritis, hand QTL GWAS1247245 (human)
RGD ID: 597151171
Trait: osteoarthritis, hand
LOD Score: Not Available
P Value: 9.0E-6
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh386161,245,158 - 161,245,159RGD_MAPPER_PIPELINEGRCh38
GRCh376161,666,190 - 161,666,191RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1247245_HHumanHand Osteoarthritis  IAGPrs12197517405850206 GWAS_CATALOGPMID:36769350

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1247245_HHumanOsteoarthritis of the small joints of the hand  IAGPrs12197517405850206 GWAS_CATALOGPMID:36769350
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1247245_HHumanosteoarthritis, hand  IAGPrs12197517405850206 GWAS_CATALOGPMID:36769350

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1354001AGPAT41-acylglycerol-3-phosphate O-acyltransferase 46161129967161274061Human


Peak: (rs12197517)
Human AssemblyChrPosition (strand)Source
GRCh386161,245,158 - 161,245,159RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597151171GWAS1247245_Hosteoarthritis, hand QTL GWAS1247245 (human)0.000009osteoarthritis, hand6161245158161245159Human
1643404BMD3_HBone mineral density QTL 3 (human)2.420.0005Bone mineral density6157563614170805979Human
597243838GWAS1339912_Hlipoprotein A measurement QTL GWAS1339912 (human)4e-18lipoprotein A measurement6161245158161245159Human
1643367BW323_HBody weight QTL 323 (human)2.420.0005Body fat amount6157563614170805979Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1247245_H GCST90270115 Hand Osteoarthritis 420 Han Chinese ancestry cases, 716 Han Chinese ancestry controls G 0.9088 0.000009 5.046 rs12197517 2.327 osteoarthritis, hand (EFO:1000789)
 PMID:36769350
GWAS1339912_H GCST90019513 Lipoprotein (a) levels 272,573 European ancestry individuals, 5,018 African ancestry individuals, 6,453 South Asian ancestry individuals C NR 4E-18 17.398 rs12197517 0.0313 lipoprotein A measurement (EFO:0006925)
 PMID:33462484
Database
Acc Id
Source(s)
GWAS Catalog GCST90270115 GWAS Catalog

Note Type Note Reference