GWAS1211092_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1211092_H (systolic blood pressure QTL GWAS1211092 (human)) Homo sapiens

Symbol: GWAS1211092_H
Name: systolic blood pressure QTL GWAS1211092 (human)
RGD ID: 597115018
Trait: systolic blood pressure
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: Not Available
P Value: 1.0E-25
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381450,269,229 - 50,269,230RGD_MAPPER_PIPELINEGRCh38
GRCh371450,735,947 - 50,735,948RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1211092_HHumansystolic blood pressure  IAGPrs72683923405850206 GWAS_CATALOGPMID:30224653

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1211092_HHumansystolic blood pressure  IAGPrs72683923405850206 GWAS_CATALOGPMID:30224653

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1314761L2HGDHL-2-hydroxyglutarate dehydrogenase145024243450312229Human


Peak: (rs72683923)
Human AssemblyChrPosition (strand)Source
GRCh381450,269,229 - 50,269,230RGD_MAPPER_PIPELINE


1 to 10 of 16 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597255547GWAS1351621_Hserum alanine aminotransferase measurement QTL GWAS1351621 (human)3e-25serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)145026922950269230Human
597096336GWAS1192410_Hsex hormone-binding globulin measurement QTL GWAS1192410 (human)6e-15sex hormone-binding globulin measurement145026922950269230Human
597425075GWAS1521149_Hsystolic blood pressure QTL GWAS1521149 (human)3e-17systolic blood pressuresystolic blood pressure (CMO:0000004)145026922950269230Human
597201809GWAS1297883_Hsystolic blood pressure QTL GWAS1297883 (human)3e-26systolic blood pressuresystolic blood pressure (CMO:0000004)145026922950269230Human
597346256GWAS1442330_Hurate measurement QTL GWAS1442330 (human)4e-15urate measurementblood uric acid level (CMO:0000501)145026922950269230Human
597168914GWAS1264988_Haspartate aminotransferase measurement QTL GWAS1264988 (human)5e-36aspartate aminotransferase measurementblood aspartate aminotransferase activity level (CMO:0000580)145026922950269230Human
597131100GWAS1227174_Hpulse pressure measurement QTL GWAS1227174 (human)2e-12mean arterial pressuremean arterial blood pressure (CMO:0000009)145026922950269230Human
597344854GWAS1440928_Hurate measurement QTL GWAS1440928 (human)2e-14urate measurementblood uric acid level (CMO:0000501)145026922950269230Human
597427442GWAS1523516_Hgout QTL GWAS1523516 (human)1e-10gout145026922950269230Human
596976314GWAS1095833_Hhypertension QTL GWAS1095833 (human)7e-09hypertension145026922950269230Human

1 to 10 of 16 rows


1 to 20 of 25 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1211092_H GCST006624 Systolic blood pressure 757,601 European ancestry individuals T 0.9797 1E-25 25 rs72683923 0.9769 systolic blood pressure (EFO:0006335)
 PMID:30224653
GWAS1711895_H GCST008747 Estimated glomerular filtration rate 70,762 European ancestry diabetic individuals, 152,624 European ancestry non-diabetic individuals, 20,967 African American diabetic individuals, 36,369 African American non-diabetic individuals T 0.979 2E-8 7.699 rs72683923 0.0076 glomerular filtration rate (OBA:0003747)
 PMID:31451708
GWAS1712246_H GCST008747 Estimated glomerular filtration rate 70,762 European ancestry diabetic individuals, 152,624 European ancestry non-diabetic individuals, 20,967 African American diabetic individuals, 36,369 African American non-diabetic individuals T 0.979 8E-9 8.097 rs72683923 0.0074 glomerular filtration rate (OBA:0003747)
 PMID:31451708
GWAS1712559_H GCST008059 Estimated glomerular filtration rate 567,460 European ancestry individuals T 0.979 1E-15 15 rs72683923 0.0076 glomerular filtration rate (OBA:0003747)
 PMID:31152163
GWAS1713164_H GCST008058 Estimated glomerular filtration rate 567,460 European ancestry individuals, 165,726 East Asian ancestry individuals, 13,842 African American individuals, 13,359 South Asian ancestry individuals, 4,961 Hispanic individuals T 0.9791 3E-15 14.523 rs72683923 0.0074 glomerular filtration rate (OBA:0003747)
 PMID:31152163
GWAS1725242_H GCST007082 Hair color approximately 452,000 European ancestry individuals ? NR 1E-14 14 rs72683923 N/A strand of hair color (OBA:0002313)
 PMID:30595370
GWAS1192410_H GCST90012108 Sex hormone-binding globulin levels adjusted for BMI 180,094 European ancestry men C 0.019684000000000035 6E-15 14.222 rs72683923 0.0290782 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS1194291_H GCST90012109 Sex hormone-binding globulin levels 180,726 European ancestry men C 0.019684000000000035 3E-16 15.523 rs72683923 0.0339786 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS1227174_H GCST90310296 Pulse pressure 1,028,980 European ancestry individuals C NR 2E-12 11.699 rs72683923 0.4542 pulse pressure measurement (EFO:0005763)
 PMID:38689001
GWAS1740785_H GCST007876 Estimated glomerular filtration rate 206,856 European ancestry individuals, 143,658 East Asian ancestry individuals C 0.0109 3E-8 7.523 rs72683923 5.542 glomerular filtration rate (OBA:0003747)
 PMID:31015462
GWAS1264988_H GCST90018944 Aspartate aminotransferase levels 342,990 European ancestry individuals, 150,068 East Asian ancestry individuals C NR 5E-36 35.302 rs72683923 0.102 aspartate aminotransferase measurement (EFO:0004736)
 PMID:34594039
GWAS1297883_H GCST90310294 Systolic blood pressure 1,028,980 European ancestry individuals C NR 3E-26 25.523 rs72683923 0.9677 systolic blood pressure (EFO:0006335)
 PMID:38689001
GWAS1297974_H GCST90310295 Diastolic blood pressure 1,028,980 European ancestry individuals C NR 1E-19 19 rs72683923 0.5099 diastolic blood pressure (EFO:0006336)
 PMID:38689001
GWAS1754677_H GCST90103634 Estimated glomerular filtration rate (creatinine) 1,004,040 European ancestry individuals T 0.9801 3E-13 12.523 rs72683923 0.0074 glomerular filtration rate (OBA:0003747)
 PMID:34272381
GWAS1755377_H GCST90103633 Estimated glomerular filtration rate (creatinine) 1,004,040 European ancestry individuals, 165,726 East Asian ancestry individuals, 13,842 African American individuals, 13,359 South Asian ancestry individuals, 4,961 Hispanic individuals, 2 individuals T 0.981280238930795 1E-24 24 rs72683923 0.009259335 glomerular filtration rate (OBA:0003747)
 PMID:34272381
GWAS1351621_H GCST90013405 Liver enzyme levels (alanine transaminase) 437,267 European ancestry individuals T 0.980228 3E-25 24.523 rs72683923 0.0143899 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:33972514
GWAS1384848_H GCST90446531 Hypertension 193,908 European ancestry cases, 265,230 European ancestry controls ? NR 7E-9 8.155 rs72683923 N/A hypertension (EFO:0000537)
 PMID:37947095
None Available GCST90018963 Mean arterial pressure 360,863 European ancestry individuals, 145,502 East Asian ancestry individuals C NR 2E-12 11.699 rs72683923 0.0573 mean arterial pressure (EFO:0006340)
 PMID:34594039
GWAS1436729_H GCST90428729 Alanine aminotransferase levels 1,010,710 European ancestry individuals C NR 5E-28 27.302 rs72683923 0.0152 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:38632349
GWAS1440928_H GCST90319906 Serum urate levels 677,373 European ancestry individuals T NR 2E-14 13.699 rs72683923 0.0781 urate measurement (EFO:0004531)
 PMID:38658550
1 to 20 of 25 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST006624 GWAS Catalog

Note Type Note Reference