GWAS1191564_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1191564_H (FEV/FVC ratio, response to bronchodilator QTL GWAS1191564 (human)) Homo sapiens

Symbol: GWAS1191564_H
Name: FEV/FVC ratio, response to bronchodilator QTL GWAS1191564 (human)
RGD ID: 597095490
Trait: FEV/FVC ratio, response to bronchodilator
Measurement Type: forced expiratory volume to forced vital capacity ratio   (CMO:0000241)    
LOD Score: Not Available
P Value: 3.0E-6
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38497,587,250 - 97,587,251RGD_MAPPER_PIPELINEGRCh38
GRCh37498,508,401 - 98,508,402RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1191564_HHumanresponse to bronchodilator  IAGPrs1532993405850206 GWAS_CATALOGPMID:26634245


Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1191564_HHumanforced expiratory volume to forced vital capacity ratio  IAGPrs1532993405850206 GWAS_CATALOGPMID:26634245

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1191564_HHumanFEV/FVC ratio  IAGPrs1532993405850206 GWAS_CATALOGPMID:26634245

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1602169STPG2sperm tail PG-rich repeat containing 249744124998143476Human


Peak: (rs1532993)
Human AssemblyChrPosition (strand)Source
GRCh38497,587,250 - 97,587,251RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597095490GWAS1191564_HFEV/FVC ratio, response to bronchodilator QTL GWAS1191564 (human)0.000003FEV/FVC ratio, response to bronchodilatorforced expiratory volume to forced vital capacity ratio (CMO:0000241)49758725097587251Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1191564_H GCST003264 Post bronchodilator FEV1/FVC ratio 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals C 0.668 0.000003 5.523 rs1532993 0.016 FEV/FVC ratio (EFO:0004713)
response to bronchodilator (GO:0097366)
 PMID:26634245
Database
Acc Id
Source(s)
GWAS Catalog GCST003264 GWAS Catalog

Note Type Note Reference