GWAS1157802_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1157802_H (systolic blood pressure QTL GWAS1157802 (human)) Homo sapiens

Symbol: GWAS1157802_H
Name: systolic blood pressure QTL GWAS1157802 (human)
RGD ID: 597061728
Trait: systolic blood pressure
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: Not Available
P Value: 4.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381918,341,385 - 18,341,386RGD_MAPPER_PIPELINEGRCh38
GRCh371918,452,195 - 18,452,196RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1157802_HHumansystolic blood pressure  IAGPrs12459965405850206 GWAS_CATALOGPMID:30595370

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1157802_HHumansystolic blood pressure  IAGPrs12459965405850206 GWAS_CATALOGPMID:30595370

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1348411PGPEP1pyroglutamyl-peptidase I191834059818369950Human


Peak: (rs12459965)
Human AssemblyChrPosition (strand)Source
GRCh381918,341,385 - 18,341,386RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1300034BP50_HBlood pressure QTL 50 (human)2.10.00094Blood pressuresystolic191108946337089463Human
597199865GWAS1295939_Hdiastolic blood pressure QTL GWAS1295939 (human)0.0000008diastolic blood pressurediastolic blood pressure (CMO:0000005)191834138518341386Human
597217659GWAS1313733_Hpulse pressure measurement QTL GWAS1313733 (human)5e-09pulse pressure measurementpulse pressure (CMO:0000292)191834138518341386Human
597618669GWAS1675529_Hhypertension QTL GWAS1675529 (human)4e-11hypertension191834138518341386Human
597348431GWAS1444505_Hsystolic blood pressure QTL GWAS1444505 (human)2e-12systolic blood pressuresystolic blood pressure (CMO:0000004)191834138518341386Human
597061728GWAS1157802_Hsystolic blood pressure QTL GWAS1157802 (human)4e-12systolic blood pressuresystolic blood pressure (CMO:0000004)191834138518341386Human
596966828GWAS1086347_Hdiastolic blood pressure QTL GWAS1086347 (human)7e-12diastolic blood pressure191834138518341386Human
597317746GWAS1413820_Hdiastolic blood pressure QTL GWAS1413820 (human)7e-12diastolic blood pressurediastolic blood pressure (CMO:0000005)191834138518341386Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1157802_H GCST007087 Systolic blood pressure approximately 422,000 European ancestry individuals ? NR 4E-12 11.398 rs12459965 N/A systolic blood pressure (EFO:0006335)
 PMID:30595370
GWAS1675529_H GCST90480128 Hypertension (PheCode 401) 94,292 African American or Afro-Caribbean cases, 22,643 African American or Afro-Caribbean controls, 35,766 Hispanic or Latin American cases, 20,913 Hispanic or Latin American controls, 3,903 East Asian ancestry cases, 2,607 East Asian ancestry controls, 322,448 European ancestry cases, 105,690 European ancestry controls C 0.7651 4E-11 10.398 rs12459965 0.04499 hypertension (EFO:0000537)
 PMID:39024449
GWAS1295939_H GCST90310295 Diastolic blood pressure 1,028,980 European ancestry individuals T NR 8E-7 6.097 rs12459965 0.0856 diastolic blood pressure (EFO:0006336)
 PMID:38689001
GWAS1313733_H GCST90310296 Pulse pressure 1,028,980 European ancestry individuals T NR 5E-9 8.302 rs12459965 0.1163 pulse pressure measurement (EFO:0005763)
 PMID:38689001
GWAS1413820_H GCST90435414 Diastolic blood pressure 404,337 European ancestry individuals ? NR 7E-12 11.155 rs12459965 0.0160613 diastolic blood pressure (EFO:0006336)
 PMID:39134668
GWAS1444505_H GCST90310294 Systolic blood pressure 1,028,980 European ancestry individuals T NR 2E-12 11.699 rs12459965 0.1949 systolic blood pressure (EFO:0006335)
 PMID:38689001
Database
Acc Id
Source(s)
GWAS Catalog GCST007087 GWAS Catalog

Note Type Note Reference