GWAS1156933_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1156933_H (FEV/FVC ratio QTL GWAS1156933 (human)) Homo sapiens

Symbol: GWAS1156933_H
Name: FEV/FVC ratio QTL GWAS1156933 (human)
RGD ID: 597060859
Trait: FEV/FVC ratio
Measurement Type: forced expiratory volume to forced vital capacity ratio   (CMO:0000241)    
LOD Score: Not Available
P Value: 3.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382205,771,399 - 205,771,400RGD_MAPPER_PIPELINEGRCh38
GRCh372206,636,123 - 206,636,124RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1156933_HHumanforced expiratory volume to forced vital capacity ratio  IAGPrs2241153405850206 GWAS_CATALOGPMID:30595370

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1156933_HHumanFEV/FVC ratio  IAGPrs2241153405850206 GWAS_CATALOGPMID:30595370

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
732191NRP2neuropilin 22205682501205798131Human


Peak: (rs2241153)
Human AssemblyChrPosition (strand)Source
GRCh382205,771,399 - 205,771,400RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2293458PRSTS291_HProstate tumor susceptibility QTL 291 (human)0.012Prostate tumor susceptibility2200715236226715236Human
1643053BW117_HBody Weight QTL 117 (human)2.40.00044Body weight2200715236226715236Human
597060859GWAS1156933_HFEV/FVC ratio QTL GWAS1156933 (human)3e-09FEV/FVC ratioforced expiratory volume to forced vital capacity ratio (CMO:0000241)2205771399205771400Human
1643254BW125_HBody Weight QTL 125 (human)1.450.005Body weightbody mass index2200715236226715236Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1156933_H GCST007080 Lung function (FEV1/FVC) approximately 370,000 European ancestry individuals ? NR 3E-9 8.523 rs2241153 N/A FEV/FVC ratio (EFO:0004713)
 PMID:30595370
None Available GCST90244094 Lung function (FEV1/FVC) 475,645 European ancestry individuals, 8,590 African ancestry individuals, 85,279 East Asian ancestry individuals, 4,270 South Asian ancestry individuals, 14,668 Hispanic or Latin American individuals A 0.383 3E-9 8.523 rs2241153 5.914 FEV/FVC ratio (EFO:0004713)
 PMID:36914875
Database
Acc Id
Source(s)
GWAS Catalog GCST007080 GWAS Catalog
  GCST90244094 GWAS Catalog

Note Type Note Reference