GWAS1115815_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1115815_H (body mass index QTL GWAS1115815 (human)) Homo sapiens

Symbol: GWAS1115815_H
Name: body mass index QTL GWAS1115815 (human)
RGD ID: 597019741
Trait: body mass index
Measurement Type: body mass index (BMI)   (CMO:0000105)    
LOD Score: Not Available
P Value: 5.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381918,344,015 - 18,344,016RGD_MAPPER_PIPELINEGRCh38
GRCh371918,454,825 - 18,454,826RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1115815_HHumanbody mass index (BMI)  IAGPrs17724992405850206 GWAS_CATALOGPMID:26426971

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1115815_HHumanbody mass index  IAGPrs17724992405850206 GWAS_CATALOGPMID:26426971

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1348411PGPEP1pyroglutamyl-peptidase I191834059818369950Human
155767264LOC127890850NANOG-H3K27ac hESC enhancer GRCh37_chr19:18454745-18455584191834393518344774Human


Peak: (rs17724992)
Human AssemblyChrPosition (strand)Source
GRCh381918,344,015 - 18,344,016RGD_MAPPER_PIPELINE


1 to 10 of 20 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597618716GWAS1675576_Hessential hypertension QTL GWAS1675576 (human)2e-11essential hypertension191834401518344016Human
597018966GWAS1115040_Hbody mass index QTL GWAS1115040 (human)0.000001body mass indexbody mass index (BMI) (CMO:0000105)191834401518344016Human
597070322GWAS1166396_Hsmoking behavior, body mass index QTL GWAS1166396 (human)0.000003smoking behavior, body mass indexbody mass index (BMI) (CMO:0000105)191834401518344016Human
597291039GWAS1387113_Hbody mass index QTL GWAS1387113 (human)9e-16body mass indexbody mass index (BMI) (CMO:0000105)191834401518344016Human
407039941GWAS688917_Hbody mass index QTL GWAS688917 (human)8e-09body mass indexbody mass index (BMI) (CMO:0000105)191834401518344016Human
596961971GWAS1081490_Hmetabolic syndrome QTL GWAS1081490 (human)4e-18metabolic syndrome191834401518344016Human
597019741GWAS1115815_Hbody mass index QTL GWAS1115815 (human)5e-08body mass indexbody mass index (BMI) (CMO:0000105)191834401518344016Human
597335152GWAS1431226_Hsmoking initiation QTL GWAS1431226 (human)2e-23smoking initiation191834401518344016Human
597319798GWAS1415872_Hsmoking initiation QTL GWAS1415872 (human)4e-21smoking initiation191834401518344016Human
597070104GWAS1166178_Hsmoking behavior, body mass index QTL GWAS1166178 (human)0.000005smoking behavior, body mass indexbody mass index (BMI) (CMO:0000105)191834401518344016Human

1 to 10 of 20 rows


1 to 19 of 19 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1115815_H GCST005951 Body mass index up to 309,889 European ancestry individuals A 0.743708279308239 5E-8 7.302 rs17724992 0.017328002 body mass index (EFO:0004340)
 PMID:26426971
GWAS1115040_H GCST002783 Body mass index up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals A 0.748 0.000001 6 rs17724992 0.023 body mass index (EFO:0004340)
 PMID:25673413
None Available GCST006802 Body mass index 29,925 British ancestry cases, 89,763 British ancestry controls A NR 0.000001 6 rs17724992 0.023 body mass index (EFO:0004340)
 PMID:26961502
GWAS1133432_H GCST006697 Parental longevity (combined parental attained age, Martingale residuals) 389,166 British ancestry individuals A 0.733 9E-7 6.046 rs17724992 0.0124 parental longevity (EFO:0007796)
 PMID:29227965
GWAS599461_H GCST002783 Body mass index up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals A 0.746 3E-8 7.523 rs17724992 0.019 body mass index (EFO:0004340)
 PMID:25673413
GWAS1166178_H GCST004495 BMI (adjusted for smoking behaviour) 98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men A 0.7369 0.000005 5.302 rs17724992 0.0174 smoking behavior (EFO:0004318)
body mass index (EFO:0004340)
 PMID:28443625
GWAS1166396_H GCST004497 Body mass index (joint analysis main effects and smoking interaction) 98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men A 0.7369 0.000003 5.523 rs17724992 N/A smoking behavior (EFO:0004318)
body mass index (EFO:0004340)
 PMID:28443625
GWAS1171033_H GCST004904 Body mass index up to 72,390 Japanese ancestry women, up to 85,894 Japanese ancestry men G 0.27 4E-12 11.398 rs17724992 0.017 body mass index (EFO:0004340)
 PMID:28892062
GWAS688917_H GCST002783 Body mass index up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals A 0.743 8E-9 8.097 rs17724992 0.02 body mass index (EFO:0004340)
 PMID:25673413
GWAS1675576_H GCST90480125 Essential hypertension (PheCode 401.1) 93,857 African American or Afro-Caribbean cases, 22,988 African American or Afro-Caribbean controls, 35,551 Hispanic or Latin American cases, 21,134 Hispanic or Latin American controls, 3,880 East Asian ancestry cases, 2,626 East Asian ancestry controls, 320,429 European ancestry cases, 107,275 European ancestry controls A 0.7622 2E-11 10.699 rs17724992 0.04283 PMID:39024449
GWAS1276025_H GCST90179150 Body mass index (MTAG) 694,649 European ancestry individuals A NR 2E-21 20.699 rs17724992 0.016995 body mass index (EFO:0004340)
 PMID:36376304
GWAS1289271_H GCST90255621 Body mass index 1,122,049 European ancestry individuals G NR 4E-28 27.398 rs17724992 0.0183 body mass index (EFO:0004340)
 PMID:36581621
GWAS1321856_H GCST006368 Body mass index 315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals A NR 5E-7 6.302 rs17724992 0.015 body mass index (EFO:0004340)
 PMID:30108127
GWAS1081490_H GCST90444487 Metabolic syndrome 1,384,348 European ancestry individuals ? NR 4E-18 17.398 rs17724992 0.0160271 metabolic syndrome (EFO:0000195)
 PMID:39349817
GWAS1387113_H GCST90446645 Body mass index 650,000 European ancestry individuals A 0.715 9E-16 15.046 rs17724992 0.0159 body mass index (EFO:0004340)
 PMID:39375568
GWAS1408460_H GCST90018972 Systolic blood pressure 340,159 European ancestry individuals, 145,505 East Asian ancestry individuals G NR 7E-12 11.155 rs17724992 0.0139 systolic blood pressure (EFO:0006335)
 PMID:34594039
GWAS1764833_H GCST90245848 Height 5,314,291 European ancestry, Hispanic or Latin American, East Asian ancestry, African ancestry, South Asian ancestry individuals G 0.2772 9E-10 9.046 rs17724992 0.0045 body height (OBA:VT0001253)
 PMID:36224396
GWAS1415872_H GCST90243968 Smoking initiation 2,669,029 European ancestry individuals G 0.262 4E-21 20.398 rs17724992 0.00928 smoking initiation (EFO:0005670)
 PMID:36477530
GWAS1431226_H GCST90243985 Smoking initiation 3,382,012 European ancestry, East Asian ancestry, Hispanic or Latin American, African ancestry individuals G 0.28 2E-23 22.699 rs17724992 0.00863 smoking initiation (EFO:0005670)
 PMID:36477530
1 to 19 of 19 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST005951 GWAS Catalog

Note Type Note Reference