GWAS1065275_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1065275_H (free cholesterol:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS1065275 (human)) Homo sapiens

Symbol: GWAS1065275_H
Name: free cholesterol:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS1065275 (human)
RGD ID: 407416299
Trait: free cholesterol:total lipids ratio, intermediate density lipoprotein measurement
Measurement Type: blood intermediate density lipoprotein cholesterol level   (CMO:0001562)    
LOD Score: Not Available
P Value: 6.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38487,260,339 - 87,260,340RGD_MAPPER_PIPELINEGRCh38
GRCh37488,181,491 - 88,181,492RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1065275_HHumanblood intermediate density lipoprotein cholesterol level  IAGPrs10020067405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1065275_HHumanfree cholesterol:total lipids ratio  IAGPrs10020067405850206 GWAS_CATALOGPMID:35213538
GWAS1065275_HHumanintermediate density lipoprotein measurement  IAGPrs10020067405850206 GWAS_CATALOGPMID:35213538
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs10020067)
Human AssemblyChrPosition (strand)Source
GRCh38487,260,339 - 87,260,340RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407417578GWAS1066554_Hphospholipid measurement, high density lipoprotein cholesterol measurement QTL GWAS1066554 (human)3e-08phospholipid measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)48726033987260340Human
407382474GWAS1031450_Hmean platelet volume QTL GWAS1031450 (human)1e-17mean platelet volumemean platelet volume (CMO:0001348)48726033987260340Human
407410570GWAS1059546_Htriglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS1059546 (human)7e-17triglyceride measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)48726033987260340Human
407416299GWAS1065275_Hfree cholesterol:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS1065275 (human)6e-09free cholesterol:total lipids ratio, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)48726033987260340Human
407417995GWAS1066971_Hvery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio QTL GWAS1066971 (human)4e-08very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)48726033987260340Human
407418303GWAS1067279_Hvery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS1067279 (human)2e-08very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)48726033987260340Human
407036858GWAS685834_Hpolyunsaturated fatty acids to total fatty acids percentage QTL GWAS685834 (human)3e-11fatty acid measurement48726033987260340Human
407408417GWAS1057393_Hsex hormone-binding globulin measurement QTL GWAS1057393 (human)2e-23sex hormone-binding globulin measurement48726033987260340Human
407023086GWAS672062_Hsex hormone-binding globulin measurement QTL GWAS672062 (human)4e-59sex hormone-binding globulin measurement48726033987260340Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS672062_H GCST90239821 Sex hormone-binding globulin levels 163,363 British ancestry men ? NR 4E-59 58.398 rs10020067 0.0528899 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:36653534
GWAS685834_H GCST90269550 Polyunsaturated fatty acids to total fatty acids percentage (UKB data field 23453) 88,268 European ancestry individuals A 0.381346 3E-11 10.523 rs10020067 0.0311212 polyunsaturated fatty acids to total fatty acids percentage (EFO:0022303)
 PMID:36764567
GWAS1031450_H GCST90002395 Mean platelet volume 408,112 British individuals A 0.380977 1E-17 17 rs10020067 0.01986019 mean platelet volume (EFO:0004584)
 PMID:32888494
GWAS1057393_H GCST90027091 Sex hormone-binding globulin levels 148,248 British ancestry men A 0.38 2E-23 22.699 rs10020067 0.81 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:34321204
GWAS1059546_H GCST90092902 Triglyceride levels in medium HDL 115,082 European ancestry individuals C 0.618559 7E-17 16.155 rs10020067 0.034765 triglyceride measurement (EFO:0004530)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90435412 Height 404,900 European ancestry individuals ? NR 4E-9 8.398 rs10020067 0.0105449 body height (EFO:0004339)
 PMID:39134668
GWAS1065275_H GCST90092836 Free cholesterol to total lipids ratio in IDL 115,082 European ancestry individuals C 0.618559 6E-9 8.222 rs10020067 0.0245294 free cholesterol:total lipids ratio (EFO:0020945)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
None Available GCST90092941 Ratio of polyunsaturated fatty acids to total fatty acids 115,006 European ancestry individuals C 0.618559 3E-11 10.523 rs10020067 0.0271278 fatty acid measurement (EFO:0005110)
 PMID:35213538
GWAS1066554_H GCST90092952 Phospholipid levels in small HDL 115,082 European ancestry individuals C 0.618559 3E-8 7.523 rs10020067 0.0233889 phospholipid measurement (EFO:0004639)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS1066971_H GCST90093017 Cholesterol to total lipids ratio in very large VLDL 114,160 European ancestry individuals C 0.618548 4E-8 7.398 rs10020067 0.0223799 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesterol:total lipids ratio (EFO:0020943)
 PMID:35213538
GWAS1067279_H GCST90093019 Cholesteryl esters to total lipids ratio in very large VLDL 114,160 European ancestry individuals C 0.618548 2E-8 7.699 rs10020067 0.0228122 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:35213538
Database Acc Id Source(s)
GWAS Catalog GCST90092836 GWAS Catalog

RGD Curation Notes
Note Type Note Reference