QTL |
GWAS Catalog Study |
Disease Trait |
Study Size |
Risk Allele |
Risk Allele Frequency |
P Value |
P Value MLOG |
Peak Marker |
Reported Odds Ratio or Beta-coefficient |
Ontology Accession |
PubMed |
GWAS703993_H |
GCST90025995 |
Serum total protein levels |
400,482 European ancestry individuals |
? |
NR |
4E-9 |
8.398 |
rs41274050 |
0.0598994 |
total blood protein measurement (EFO:0004536)
|
PMID:34226706 |
None Available |
GCST008074 |
Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) |
44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers |
T |
NR |
4E-9 |
8.398 |
rs41274050 |
N/A |
triglyceride measurement (EFO:0004530) alcohol consumption measurement (EFO:0007878)
|
PMID:30698716 |
GWAS719426_H |
GCST009152 |
Triglyceride levels |
up to 237,050 European ancestry individuals, up to 16,935 African ancestry individuals, up to 30,468 South Asian ancestry individuals, up to 8,287 East Asian ancestry individuals, 5,084 Hispanic individuals |
T |
NR |
5E-19 |
18.302 |
rs41274050 |
0.095279835 |
triglyceride measurement (EFO:0004530)
|
PMID:29083408 |
None Available |
GCST009149 |
Triglyceride levels |
up to 237,050 European ancestry individuals |
T |
0.0085 |
4E-9 |
8.398 |
rs41274050 |
0.097 |
triglyceride measurement (EFO:0004530)
|
PMID:29083408 |
GWAS723000_H |
GCST010173 |
Triglyceride levels |
324,694 British ancestry individuals |
? |
NR |
4E-19 |
18.398 |
rs41274050 |
0.1172 |
triglyceride measurement (EFO:0004530)
|
PMID:32154731 |
GWAS723686_H |
GCST008087 |
Triglyceride levels in current drinkers |
56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals |
T |
NR |
7E-7 |
6.155 |
rs41274050 |
0.106 |
triglyceride measurement (EFO:0004530)
|
PMID:30698716 |
GWAS726390_H |
GCST010204 |
Low density lipoprotein cholesterol levels |
324,708 British ancestry individuals |
? |
NR |
4E-13 |
12.398 |
rs41274050 |
0.0932 |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:32154731 |
GWAS1020590_H |
GCST006614 |
Total cholesterol levels |
215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals |
T |
0.0088 |
6E-13 |
12.222 |
rs41274050 |
0.1069 |
total cholesterol measurement (EFO:0004574)
|
PMID:30275531 |
None Available |
GCST006613 |
Triglycerides |
215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals |
T |
0.0089 |
4E-9 |
8.398 |
rs41274050 |
0.0881 |
triglyceride measurement (EFO:0004530)
|
PMID:30275531 |
GWAS1024425_H |
GCST008074 |
Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) |
44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers |
T |
NR |
1E-9 |
9 |
rs41274050 |
N/A |
triglyceride measurement (EFO:0004530) alcohol consumption measurement (EFO:0007878)
|
PMID:30698716 |
GWAS1026002_H |
GCST008087 |
Triglyceride levels in current drinkers |
56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals |
T |
NR |
2E-7 |
6.699 |
rs41274050 |
0.108 |
triglyceride measurement (EFO:0004530)
|
PMID:30698716 |
GWAS1039295_H |
GCST90025966 |
Gamma glutamyl transferase levels |
437,651 European ancestry individuals |
? |
NR |
3E-20 |
19.523 |
rs41274050 |
0.0891211 |
serum gamma-glutamyl transferase measurement (EFO:0004532)
|
PMID:34226706 |
GWAS1039382_H |
GCST90025953 |
Total cholesterol levels |
437,878 European ancestry individuals |
? |
NR |
3E-13 |
12.523 |
rs41274050 |
0.0790005 |
total cholesterol measurement (EFO:0004574)
|
PMID:34226706 |
GWAS1039389_H |
GCST90025952 |
Apolipoprotein B levels |
435,744 European ancestry individuals |
? |
NR |
1E-22 |
22 |
rs41274050 |
0.100615 |
apolipoprotein B measurement (EFO:0004615)
|
PMID:34226706 |
GWAS1040064_H |
GCST90019496 |
Apolipoprotein B levels |
340,860 European ancestry individuals, 5,962 African ancestry individuals, 7,275 South Asian ancestry individuals |
T |
NR |
7E-23 |
22.155 |
rs41274050 |
0.1194 |
apolipoprotein B measurement (EFO:0004615)
|
PMID:33462484 |
None Available |
GCST90025990 |
Calcium levels |
400,792 European ancestry individuals |
? |
NR |
4E-9 |
8.398 |
rs41274050 |
0.0650605 |
calcium measurement (EFO:0004838)
|
PMID:34226706 |
None Available |
GCST90104007 |
Familial combined hyperlipidemia defined by Mexico criteria |
5,153 British ancestry cases, 344,069 British ancestry controls |
C |
0.989956 |
2E-7 |
6.699 |
rs41274050 |
0.45078 |
|
PMID:34906840 |
GWAS1040889_H |
GCST90025973 |
Bilirubin levels |
436,055 European ancestry individuals |
? |
NR |
2E-9 |
8.699 |
rs41274050 |
0.0521892 |
bilirubin measurement (EFO:0004570)
|
PMID:34226706 |
None Available |
GCST90104006 |
Familial combined hyperlipidemia defined by Consensus criteria |
39,961 British ancestry cases, 309,261 British ancestry controls |
C |
0.989956 |
2E-9 |
8.699 |
rs41274050 |
0.219299 |
|
PMID:34906840 |
GWAS1043971_H |
GCST90104005 |
Familial combined hyperlipidemia defined by Dutch criteria |
17,485 British ancestry cases, 331,737 British ancestry controls |
C |
0.989956 |
5E-10 |
9.302 |
rs41274050 |
0.316017 |
|
PMID:34906840 |
GWAS1044071_H |
GCST90239658 |
Low density lipoprotein cholesterol levels |
1,320,016 European ancestry individuals |
T |
0.00861819 |
5E-15 |
14.302 |
rs41274050 |
0.070494 |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:34887591 |
GWAS1045033_H |
GCST90239667 |
Non-HDL cholesterol levels |
40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals |
? |
NR |
2E-16 |
15.699 |
rs41274050 |
N/A |
non-high density lipoprotein cholesterol measurement (EFO:0005689)
|
PMID:34887591 |
GWAS1045257_H |
GCST90239661 |
Triglyceride levels |
40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals |
? |
NR |
3E-27 |
26.523 |
rs41274050 |
N/A |
triglyceride measurement (EFO:0004530)
|
PMID:34887591 |
GWAS1045828_H |
GCST90239673 |
Total cholesterol levels |
40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals |
? |
NR |
2E-24 |
23.699 |
rs41274050 |
N/A |
total cholesterol measurement (EFO:0004574)
|
PMID:34887591 |
GWAS1046612_H |
GCST90239655 |
Low density lipoprotein cholesterol levels |
40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals |
? |
NR |
1E-18 |
18 |
rs41274050 |
N/A |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:34887591 |
GWAS1047266_H |
GCST90239670 |
Non-HDL cholesterol levels |
1,320,016 European ancestry individuals |
T |
0.0084944 |
2E-14 |
13.699 |
rs41274050 |
0.084201 |
non-high density lipoprotein cholesterol measurement (EFO:0005689)
|
PMID:34887591 |
GWAS1048923_H |
GCST90239676 |
Total cholesterol levels |
1,320,016 European ancestry individuals |
T |
0.00857066 |
1E-17 |
17 |
rs41274050 |
0.0772404 |
total cholesterol measurement (EFO:0004574)
|
PMID:34887591 |
GWAS1049429_H |
GCST90025954 |
Direct low density lipoprotein cholesterol levels |
437,068 European ancestry individuals |
? |
NR |
5E-12 |
11.302 |
rs41274050 |
0.0729367 |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:34226706 |
GWAS1049887_H |
GCST90025957 |
Triglyceride levels |
437,532 European ancestry individuals |
? |
NR |
3E-29 |
28.523 |
rs41274050 |
0.116859 |
triglyceride measurement (EFO:0004530)
|
PMID:34226706 |
GWAS1051669_H |
GCST006612 |
LDL cholesterol |
215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals |
T |
0.0088 |
6E-10 |
9.222 |
rs41274050 |
0.0923 |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:30275531 |
GWAS1054625_H |
GCST90019501 |
Total cholesterol levels |
342,508 European ancestry individuals, 6,014 African ancestry individuals, 7,336 South Asian ancestry individuals |
T |
NR |
3E-14 |
13.523 |
rs41274050 |
0.0922 |
total cholesterol measurement (EFO:0004574)
|
PMID:33462484 |
GWAS1054675_H |
GCST90019523 |
Triglyceride levels |
342,233 European ancestry individuals, 6,014 African ancestry individuals, 7,330 South Asian ancestry individuals |
T |
NR |
2E-25 |
24.699 |
rs41274050 |
0.1265 |
triglyceride measurement (EFO:0004530)
|
PMID:33462484 |
GWAS1054680_H |
GCST90019512 |
Low density lipoprotein cholesterol levels |
341,875 European ancestry individuals, 6,003 African ancestry individuals, 7,319 South Asian ancestry individuals |
T |
NR |
1E-14 |
14 |
rs41274050 |
0.0935 |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:33462484 |
GWAS1056428_H |
GCST90019507 |
Gamma glutamyl transferase levels |
342,339 European ancestry individuals, 6,015 African ancestry individuals, 7,336 South Asian ancestry individuals |
T |
NR |
2E-13 |
12.699 |
rs41274050 |
0.0887 |
serum gamma-glutamyl transferase measurement (EFO:0004532)
|
PMID:33462484 |
GWAS1059514_H |
GCST90092974 |
Total lipid levels in small VLDL |
115,082 European ancestry individuals |
C |
0.990137 |
2E-8 |
7.699 |
rs41274050 |
0.116714 |
very low density lipoprotein cholesterol measurement (EFO:0008317) lipid measurement (EFO:0004529)
|
PMID:35213538 |
GWAS1059517_H |
GCST90092975 |
Concentration of small VLDL particles |
115,082 European ancestry individuals |
C |
0.990137 |
1E-8 |
8 |
rs41274050 |
0.118137 |
very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
GWAS1059538_H |
GCST90092890 |
Triglyceride levels in LDL |
115,082 European ancestry individuals |
C |
0.990137 |
8E-10 |
9.097 |
rs41274050 |
0.125953 |
triglyceride measurement (EFO:0004530) low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:35213538 |
None Available |
GCST90092866 |
Triglyceride levels in large LDL |
115,082 European ancestry individuals |
C |
0.990137 |
5E-10 |
9.302 |
rs41274050 |
0.127525 |
triglyceride measurement (EFO:0004530) low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:35213538 |
None Available |
GCST90092978 |
Triglyceride levels in small VLDL |
115,082 European ancestry individuals |
C |
0.990137 |
1E-8 |
8 |
rs41274050 |
0.114685 |
triglyceride measurement (EFO:0004530) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
GWAS1060907_H |
GCST90244680 |
Triglyceride levels in non-type 2 diabetes |
402,944 European ancestry individuals |
? |
NR |
2E-27 |
26.699 |
rs41274050 |
N/A |
triglyceride measurement (EFO:0004530)
|
PMID:36269708 |
GWAS1061703_H |
GCST90239664 |
Triglyceride levels |
1,320,016 European ancestry individuals |
T |
0.00858321 |
3E-19 |
18.523 |
rs41274050 |
0.0860984 |
triglyceride measurement (EFO:0004530)
|
PMID:34887591 |
GWAS1063268_H |
GCST90018975 |
Triglycerides |
343,992 European ancestry individuals, 111,667 East Asian ancestry individuals |
T |
NR |
4E-23 |
22.398 |
rs41274050 |
0.1151 |
triglyceride measurement (EFO:0004530)
|
PMID:34594039 |
GWAS1063936_H |
GCST90018961 |
LDL cholesterol |
343,621 European ancestry individuals, 72,866 East Asian ancestry individuals |
T |
NR |
5E-9 |
8.302 |
rs41274050 |
0.069 |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:34594039 |
GWAS1064285_H |
GCST90092902 |
Triglyceride levels in medium HDL |
115,082 European ancestry individuals |
C |
0.990137 |
5E-8 |
7.302 |
rs41274050 |
0.112118 |
triglyceride measurement (EFO:0004530) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
None Available |
GCST90092914 |
Triglyceride levels in medium LDL |
115,082 European ancestry individuals |
C |
0.990137 |
2E-9 |
8.699 |
rs41274050 |
0.123116 |
triglyceride measurement (EFO:0004530) low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:35213538 |
GWAS1065932_H |
GCST90092841 |
Triglyceride levels in IDL |
115,082 European ancestry individuals |
C |
0.990137 |
2E-10 |
9.699 |
rs41274050 |
0.129833 |
triglyceride measurement (EFO:0004530) intermediate density lipoprotein measurement (EFO:0008595)
|
PMID:35213538 |
None Available |
GCST90092954 |
Triglyceride levels in small HDL |
115,082 European ancestry individuals |
C |
0.990137 |
2E-9 |
8.699 |
rs41274050 |
0.121202 |
triglyceride measurement (EFO:0004530) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
None Available |
GCST90092966 |
Triglyceride levels in small LDL |
115,082 European ancestry individuals |
C |
0.990137 |
5E-8 |
7.302 |
rs41274050 |
0.110923 |
triglyceride measurement (EFO:0004530) low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:35213538 |
None Available |
GCST90093038 |
Triglyceride levels in very small VLDL |
115,082 European ancestry individuals |
C |
0.990137 |
2E-10 |
9.699 |
rs41274050 |
0.130655 |
triglyceride measurement (EFO:0004530) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
GWAS1068103_H |
GCST90092829 |
Triglyceride levels in HDL |
115,082 European ancestry individuals |
C |
0.990137 |
4E-8 |
7.398 |
rs41274050 |
0.112963 |
triglyceride measurement (EFO:0004530) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |