GWAS1031482_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1031482_H (obsolete_red blood cell distribution width QTL GWAS1031482 (human)) Homo sapiens

Symbol: GWAS1031482_H
Name: obsolete_red blood cell distribution width QTL GWAS1031482 (human)
RGD ID: 407382506
Trait: obsolete_red blood cell distribution width
Measurement Type: red blood cell distribution width- standard deviation   (CMO:0003232)    
red blood cell distribution width-coefficient of variation   (CMO:0000041)    
LOD Score: Not Available
P Value: 2.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381532,709,533 - 32,709,534RGD_MAPPER_PIPELINEGRCh38
GRCh371533,001,734 - 33,001,735RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1031482_HHumanred blood cell distribution width- standard deviation  IAGPrs58658771405850206Based on the EFO term IDGWAS_CATALOGPMID:30595370
GWAS1031482_HHumanred blood cell distribution width-coefficient of variation  IAGPrs58658771405850206Based on the EFO term IDGWAS_CATALOGPMID:30595370

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1031482_HHumanobsolete_red blood cell distribution width  IAGPrs58658771405850206 GWAS_CATALOGPMID:30595370
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs58658771)
Human AssemblyChrPosition (strand)Source
GRCh381532,709,533 - 32,709,534RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
407084610GWAS733586_Hobsolete_red blood cell distribution width QTL GWAS733586 (human)2e-11obsolete_red blood cell distribution widthred blood cell distribution width- standard deviation (CMO:0003232)153270953332709534Human
407382506GWAS1031482_Hobsolete_red blood cell distribution width QTL GWAS1031482 (human)2e-09obsolete_red blood cell distribution widthred blood cell distribution width- standard deviation (CMO:0003232)153270953332709534Human
406972643GWAS621619_Hmean corpuscular hemoglobin QTL GWAS621619 (human)2e-14mean corpuscular hemoglobinmean corpuscular hemoglobin (CMO:0000290)153270953332709534Human
406972867GWAS621843_Hmean corpuscular volume QTL GWAS621843 (human)1e-11mean corpuscular volumemean corpuscular volume (CMO:0000038)153270953332709534Human
406962530GWAS611506_Hmean corpuscular hemoglobin concentration QTL GWAS611506 (human)4e-15mean corpuscular hemoglobin concentrationmean corpuscular hemoglobin concentration (CMO:0000291)153270953332709534Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
407357379GWAS1006355_Hcolorectal cancer, colorectal adenoma QTL GWAS1006355 (human)6e-37colorectal cancer, colorectal adenoma153270953332709534Human
407371886GWAS1020862_Hcolorectal cancer QTL GWAS1020862 (human)1e-10colorectal cancer153270953332709534Human
406961706GWAS610682_Hmean corpuscular volume QTL GWAS610682 (human)8e-14mean corpuscular volumemean corpuscular volume (CMO:0000038)153270953332709534Human
407300331GWAS949307_Hcolorectal cancer QTL GWAS949307 (human)1e-13colorectal cancer153270953332709534Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
406962228GWAS611204_Hcancer QTL GWAS611204 (human)5e-08cancer153270953332709534Human
406962871GWAS611847_Hrectum cancer QTL GWAS611847 (human)1e-08rectum cancer153270953332709534Human
407254385GWAS903361_Hcolorectal carcinoma QTL GWAS903361 (human)2e-16colorectal carcinoma153270953332709534Human
406965721GWAS614697_Hmean corpuscular hemoglobin QTL GWAS614697 (human)5e-11mean corpuscular hemoglobinmean corpuscular hemoglobin (CMO:0000290)153270953332709534Human
406971352GWAS620328_Hgremlin-1 measurement QTL GWAS620328 (human)2e-1394gremlin-1 measurement153270953332709534Human
1643523BW284_HBody Weight QTL 284 (human)1.950.0013Body weight152179288947792889Human
407386869GWAS1035845_Hobsolete_red blood cell distribution width QTL GWAS1035845 (human)4e-11obsolete_red blood cell distribution widthred blood cell distribution width- standard deviation (CMO:0003232)153270953332709534Human
406959836GWAS608812_Hmean corpuscular hemoglobin concentration QTL GWAS608812 (human)3e-16mean corpuscular hemoglobin concentrationmean corpuscular hemoglobin concentration (CMO:0000291)153270953332709534Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS608812_H GCST90002322 Mean corpuscular hemoglobin 486,823 European ancestry individuals A 0.181841 3E-16 15.523 rs58658771 0.020493 mean corpuscular hemoglobin concentration (EFO:0004528)
 PMID:32888493
GWAS610682_H GCST90002334 Mean corpuscular volume 544,127 European ancestry individuals A 0.181676 8E-14 13.097 rs58658771 0.017685 mean corpuscular volume (EFO:0004526)
 PMID:32888493
GWAS611204_H GCST90011822 Cancer (pleiotropy) 64,962 European ancestry cases, 410,350 European ancestry controls A NR 5E-8 7.302 rs58658771 1.1641443 PMID:32887889
GWAS611506_H GCST90002326 Mean corpuscular hemoglobin 630,125 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals A 0.278069 4E-15 14.398 rs58658771 N/A mean corpuscular hemoglobin concentration (EFO:0004528)
 PMID:32888493
GWAS611847_H GCST90011810 Rectal cancer 2,091 European ancestry cases, 410,350 European ancestry controls A NR 1E-8 8 rs58658771 1.242236 rectum cancer (EFO:1000657)
 PMID:32887889
GWAS614697_H GCST007068 Mean corpuscular hemoglobin approximately 443,000 European ancestry individuals ? NR 5E-11 10.302 rs58658771 N/A mean corpuscular hemoglobin (EFO:0004527)
 PMID:30595370
GWAS620328_H GCST90247812 Gremlin-1 levels 10,708 European ancestry individuals A 0.18 2E-1394 1393.699 rs58658771 1.105 gremlin-1 measurement (EFO:0020421)
 PMID:34648354
GWAS621619_H GCST90002390 Mean corpuscular hemoglobin 408,112 British individuals A 0.180361 2E-14 13.699 rs58658771 0.022046117 mean corpuscular hemoglobin (EFO:0004527)
 PMID:32888494
GWAS621843_H GCST90002338 Mean corpuscular volume 696,882 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals A 0.269919 1E-11 11 rs58658771 N/A mean corpuscular volume (EFO:0004526)
 PMID:32888493
None Available GCST90002369 Red cell distribution width 531,774 European ancestry individuals T 0.818998 4E-11 10.398 rs58658771 0.016172 Red cell distribution width (EFO:0009188)
 PMID:32888493
None Available GCST007074 Red cell distribution width approximately 445,000 European ancestry individuals ? NR 2E-9 8.699 rs58658771 N/A Red cell distribution width (EFO:0009188)
 PMID:30595370
GWAS903361_H GCST90432151 ICD10 C18, C19, C20: colorectal cancer 116,382 European ancestry cases, 213,325 European ancestry controls ? NR 2E-16 15.699 rs58658771 1.21 colorectal carcinoma (EFO:1001951)
 PMID:37965154
GWAS949307_H GCST90428118 Colorectal cancer 4,988 European ancestry cases, 310,272 European ancestry controls A NR 1E-13 13 rs58658771 0.185785 PMID:38538606
GWAS1006355_H GCST007856 Colorectal cancer or advanced adenoma 55,105 European ancestry cases, 3,026 East Asian ancestry cases, 65,079 European ancestry controls, 2,268 East Asian ancestry controls A 0.1937 6E-37 36.222 rs58658771 1.15 colorectal adenoma (EFO:0005406)
 PMID:30510241
None Available GCST008372 Colorectal cancer (PheCode 153) 4,562 British ancestry cases, 382,756 British ancestry controls A 0.179 1E-10 10 rs58658771 N/A PMID:30104761
None Available GCST90002404 Red cell distribution width 408,112 British individuals A 0.180413 2E-11 10.699 rs58658771 0.019378273 Red cell distribution width (EFO:0009188)
 PMID:32888494
Database Acc Id Source(s)
GWAS Catalog GCST007074 GWAS Catalog

RGD Curation Notes
Note Type Note Reference