References
References - curated
Region Genes in Region
RGD ID | Symbol | Name | Chr | Start | Stop | Species | 1318158 | TM6SF2 | transmembrane 6 superfamily member 2 | 19 | 19264366 | 19273301 | Human | |
Position Markers
Peak: (rs58542926) |
|
QTLs in Region (GRCh38)
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
Additional Information
GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog | ||
The highlighted row represents the current QTL |
QTL | GWAS Catalog Study | Disease Trait | Study Size | Risk Allele | Risk Allele Frequency | P Value | P Value MLOG | Peak Marker | Reported Odds Ratio or Beta-coefficient | Ontology Accession | PubMed |
GWAS555240_H | GCST007141 | Low density lipoprotein cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | C | NR | 1E-15 | 15 | rs58542926 | 0.067 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:29507422 |
GWAS555896_H | GCST007141 | Low density lipoprotein cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | C | 0.927 | 6E-15 | 14.222 | rs58542926 | 0.071 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:29507422 |
GWAS556570_H | GCST007142 | Triglycerides | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | C | NR | 7E-47 | 46.155 | rs58542926 | 0.108 | triglyceride measurement (EFO:0004530) |
PMID:29507422 |
GWAS556832_H | GCST007142 | Triglycerides | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | C | 0.927 | 4E-37 | 36.398 | rs58542926 | 0.103 | triglyceride measurement (EFO:0004530) |
PMID:29507422 |
GWAS556837_H | GCST007142 | Triglycerides | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | C | 0.947 | 5E-7 | 6.302 | rs58542926 | 0.156 | triglyceride measurement (EFO:0004530) |
PMID:29507422 |
GWAS557598_H | GCST007143 | Total cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | C | 0.927 | 3E-27 | 26.523 | rs58542926 | 0.097 | total cholesterol measurement (EFO:0004574) |
PMID:29507422 |
GWAS557604_H | GCST007143 | Total cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | C | NR | 2E-30 | 29.699 | rs58542926 | 0.095 | total cholesterol measurement (EFO:0004574) |
PMID:29507422 |
GWAS643692_H | GCST90002304 | Hematocrit | 562,259 European ancestry individuals | T | 0.074518 | 1E-18 | 18 | rs58542926 | 0.031578 | hematocrit (EFO:0004348) |
PMID:32888493 |
None Available | GCST90002310 | Hemoglobin concentration | 563,946 European ancestry individuals | T | 0.074553 | 1E-15 | 15 | rs58542926 | 0.028746 | hemoglobin measurement (EFO:0004509) |
PMID:32888493 |
GWAS651293_H | GCST90002314 | Hemoglobin concentration | 746,431 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals | T | 0.0743459 | 2E-13 | 12.699 | rs58542926 | N/A | hemoglobin measurement (EFO:0004509) |
PMID:32888493 |
GWAS651484_H | GCST90002308 | Hematocrit | 737,823 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals | T | 0.0743341 | 6E-16 | 15.222 | rs58542926 | N/A | hematocrit (EFO:0004348) |
PMID:32888493 |
GWAS654310_H | GCST90002383 | Hematocrit | 408,112 British individuals | T | 0.074784 | 4E-17 | 16.398 | rs58542926 | 0.03527309 | hematocrit (EFO:0004348) |
PMID:32888494 |
GWAS655356_H | GCST90002384 | Hemoglobin | 408,112 British individuals | T | 0.074789 | 3E-14 | 13.523 | rs58542926 | 0.032004 | hemoglobin measurement (EFO:0004509) |
PMID:32888494 |
GWAS662911_H | GCST006003 | Triglyceride levels | 105,597 Japanese ancestry individuals | ? | NR | 9E-14 | 13.046 | rs58542926 | 0.06384 | triglyceride measurement (EFO:0004530) |
PMID:29403010 |
GWAS726062_H | GCST010244 | Triglyceride levels | 441,016 European ancestry individuals | C | 0.925394 | 1E-162 | 162 | rs58542926 | 0.102936 | triglyceride measurement (EFO:0004530) |
PMID:32203549 |
GWAS739506_H | GCST010204 | Low density lipoprotein cholesterol levels | 324,708 British ancestry individuals | ? | NR | 3E-186 | 185.523 | rs58542926 | 0.1369 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:32154731 |
GWAS739636_H | GCST010173 | Triglyceride levels | 324,694 British ancestry individuals | ? | NR | 4E-95 | 94.398 | rs58542926 | 0.1024 | triglyceride measurement (EFO:0004530) |
PMID:32154731 |
GWAS741319_H | GCST009364 | Triglyceride levels x long total sleep time interaction (2df test) | at least 2,926 African American long sleepers, 364 Chinese ancestry long sleepers, 112 Asian ancestry long sleepers, at least 7,664 European ancestry long sleepers, 1,038 Hispanic/Latino long sleepers, up to 11,906 African American controls, 1,449 Chinese ancestry controls, 454 Asian ancestry controls, at least 31,986 European ancestry controls, 4,091 Hispanic/Latino controls | ? | NR | 5E-30 | 29.302 | rs58542926 | 0.05091 | sleep duration (EFO:0005271) triglyceride measurement (EFO:0004530) |
PMID:31719535 |
GWAS741748_H | GCST010144 | Serum 25-Hydroxyvitamin D levels | 443,734 European ancestry individuals | T | 0.075847 | 9E-19 | 18.046 | rs58542926 | 0.032488 | vitamin D measurement (EFO:0004631) |
PMID:32059762 |
GWAS743337_H | GCST009777 | C-reactive protein levels | 418,642 British ancestry individuals | C | 0.924821 | 1E-25 | 25 | rs58542926 | 0.0388777 | C-reactive protein measurement (EFO:0004458) |
PMID:31900758 |
GWAS743698_H | GCST010083 | Hemoglobin levels | 684,122 European ancestry individuals | T | NR | 2E-10 | 9.699 | rs58542926 | 0.026 | hemoglobin measurement (EFO:0004509) |
PMID:32327693 |
GWAS745953_H | GCST009363 | Triglyceride levels x short total sleep time interaction (2df test) | 2,990 African American short sleepers, 369 Chinese ancestry short sleepers, 114 Asian ancestry short sleepers, at least 8,300 European ancestry short sleepers, 1,082 Hispanic/Latino short sleepers, at least 11,842 African American controls, 1,444 Chinese ancestry controls, 452 Asian ancestry controls, at least 31,350 European ancestry controls, 4,047 Hispanic/Latino controls | ? | NR | 5E-32 | 31.302 | rs58542926 | 0.04984 | sleep duration (EFO:0005271) triglyceride measurement (EFO:0004530) |
PMID:31719535 |
GWAS748450_H | GCST007286 | Triglycerides x physical activity interaction (2df test) | 7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals | T | 0.0692 | 3E-72 | 71.523 | rs58542926 | N/A | triglyceride measurement (EFO:0004530) physical activity (EFO:0003940) |
PMID:30670697 |
GWAS761754_H | GCST90091033 | Nonalcoholic fatty liver disease | 8,434 European ancestry cases, 770,180 European ancestry controls | T | NR | 7E-17 | 16.155 | rs58542926 | 0.2676 | non-alcoholic fatty liver disease (EFO:0003095) |
PMID:34841290 |
GWAS770167_H | GCST002896 | Cholesterol, total | up to 62,166 European ancestry individuals | C | 0.92 | 8E-29 | 28.097 | rs58542926 | 0.122 | total cholesterol measurement (EFO:0004574) |
PMID:25961943 |
GWAS772082_H | GCST002897 | Triglycerides | up to 62,166 European ancestry individuals | C | 0.92 | 2E-25 | 24.699 | rs58542926 | 0.116 | triglyceride measurement (EFO:0004530) |
PMID:25961943 |
GWAS794787_H | GCST010861 | Nonalcoholic steatohepatitis | 836 European ancestry cases, 17,781 European ancestry controls | ? | NR | 2E-7 | 6.699 | rs58542926 | 1.606 | non-alcoholic steatohepatitis (EFO:1001249) |
PMID:32298765 |
GWAS795786_H | GCST010557 | Type 2 diabetes | 148,726 European ancestry cases, 24,646 African American cases, 8,616 Hispanic cases, 46,511 Asian ancestry cases, 965,732 European ancestry controls, 31,446 African American controls, 11,829 Hispanic controls, 169,776 Asian ancestry controls | C | 0.9258 | 2E-23 | 22.699 | rs58542926 | 0.0721 | PMID:32541925 | |
GWAS797929_H | GCST010555 | Type 2 diabetes | 148,726 European ancestry cases, 965,732 European ancestry controls | C | 0.9245 | 5E-25 | 24.302 | rs58542926 | 0.089 | PMID:32541925 | |
GWAS800449_H | GCST90011898 | Alanine aminotransferase levels | 390,812 European ancestry individuals | T | 0.075 | 1E-71 | 71 | rs58542926 | 17.9 | serum alanine aminotransferase measurement (EFO:0004735) |
PMID:33547301 |
GWAS803284_H | GCST90011899 | Aspartate aminotransferase levels | 389,565 European ancestry individuals | T | 0.075 | 9E-41 | 40.046 | rs58542926 | 13.4 | aspartate aminotransferase measurement (EFO:0004736) |
PMID:33547301 |
GWAS803433_H | GCST90011900 | Serum alkaline phosphatase levels | 390,964 European ancestry individuals | C | 0.92 | 3E-70 | 69.523 | rs58542926 | 17.7 | alkaline phosphatase measurement (EFO:0004533) |
PMID:33547301 |
None Available | GCST008046 | Triglyceride levels | 9,980 African American individuals, 17,856 Hispanic/Latino individuals, 2,381 Asian ancestry individuals, 1,915 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 360 individuals | ? | NR | 1E-15 | 15 | rs58542926 | 0.07220495 | triglyceride measurement (EFO:0004530) |
PMID:31217584 |
GWAS819769_H | GCST008045 | Total cholesterol levels | 10,137 African American individuals, 17,802 Hispanic/Latino individuals, 2,387 Asian ancestry individuals, 1,915 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 340 individuals | ? | NR | 1E-8 | 8 | rs58542926 | 4.359252 | total cholesterol measurement (EFO:0004574) |
PMID:31217584 |
GWAS822122_H | GCST010096 | Nonalcoholic fatty liver disease | 2,448 African American individuals, 1,365 European ancestry individuals, 753 Hispanic individuals, 141 other ancestries individuals | ? | NR | 6E-8 | 7.222 | rs58542926 | N/A | non-alcoholic fatty liver disease (EFO:0003095) |
PMID:24531328 |
GWAS825705_H | GCST90133364 | Total omega-6 fatty acid levels | 114,999 European ancestry individuals | C | 0.93 | 3E-62 | 61.523 | rs58542926 | 0.128 | omega-6 polyunsaturated fatty acid measurement (EFO:0005680) |
PMID:35692035 |
GWAS826018_H | GCST90239663 | Triglyceride levels | 146,492 East Asian ancestry individuals | T | 0.0669505 | 3E-17 | 16.523 | rs58542926 | 0.089976 | triglyceride measurement (EFO:0004530) |
PMID:34887591 |
GWAS827758_H | GCST90239664 | Triglyceride levels | 1,320,016 European ancestry individuals | T | 0.075142 | 7E-246 | 245.155 | rs58542926 | 0.108022 | triglyceride measurement (EFO:0004530) |
PMID:34887591 |
GWAS828855_H | GCST90133362 | Total omega-3 fatty acid levels | 114,999 European ancestry individuals | C | 0.93 | 1E-108 | 108 | rs58542926 | 0.172 | omega-3 polyunsaturated fatty acid measurement (EFO:0010119) |
PMID:35692035 |
GWAS833276_H | GCST90133363 | Linoleic acid levels | 114,999 European ancestry individuals | C | 0.93 | 7E-46 | 45.155 | rs58542926 | 0.11 | linoleic acid measurement (EFO:0006807) |
PMID:35692035 |
GWAS833382_H | GCST90179149 | Triglyceride levels (MTAG) | 361,194 European ancestry individuals | T | NR | 1E-93 | 93 | rs58542926 | 0.09637 | triglyceride measurement (EFO:0004530) |
PMID:36376304 |
GWAS834389_H | GCST90246696 | Beta-hexosaminidase subunit beta levels | 10,708 European ancestry individuals | T | 0.08 | 2E-29 | 28.699 | rs58542926 | 0.277 | protein measurement (EFO:0004747) |
PMID:34648354 |
GWAS835614_H | GCST90246548 | Apolipoprotein C-III levels | 10,708 European ancestry individuals | T | 0.08 | 1E-13 | 13 | rs58542926 | 0.183 | protein measurement (EFO:0004747) |
PMID:34648354 |
GWAS841286_H | GCST90248900 | Prenylcysteine oxidase 1 levels | 10,708 European ancestry individuals | T | 0.08 | 3E-58 | 57.523 | rs58542926 | 0.396 | protein measurement (EFO:0004747) |
PMID:34648354 |
GWAS848176_H | GCST90247157 | Cysteine-rich protein 1 levels | 10,708 European ancestry individuals | T | 0.08 | 1E-12 | 12 | rs58542926 | 0.171 | protein measurement (EFO:0004747) |
PMID:34648354 |
GWAS849716_H | GCST90269499 | Remnant cholesterol (non-HDL, non-LDL -cholesterol) levels (UKB data field 23402) | 88,329 European ancestry individuals | T | 0.0746244 | 3E-38 | 37.523 | rs58542926 | 0.11576 | remnant cholesterol measurement (EFO:0010815) |
PMID:36764567 |
GWAS850660_H | GCST90269500 | VLDL cholesterol levels (UKB data field 23403) | 88,329 European ancestry individuals | T | 0.0746244 | 8E-43 | 42.097 | rs58542926 | 0.12338 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:36764567 |
GWAS850668_H | GCST90269501 | Clinical LDL cholesterol levels (UKB data field 23404) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-27 | 26.699 | rs58542926 | 0.0972624 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36764567 |
None Available | GCST90269502 | LDL cholesterol levels (UKB data field 23405) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-29 | 28.699 | rs58542926 | 0.10113 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36764567 |
GWAS853041_H | GCST90269497 | Total cholesterol levels (UKB data field 23400) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-28 | 27.699 | rs58542926 | 0.0966684 | total cholesterol measurement (EFO:0004574) |
PMID:36764567 |
GWAS853342_H | GCST90269498 | Total cholesterol minus HDL-C levels (UKB data field 23401) | 88,329 European ancestry individuals | T | 0.0746244 | 1E-34 | 34 | rs58542926 | 0.110155 | total cholesterol measurement (EFO:0004574) |
PMID:36764567 |
GWAS854948_H | GCST90269517 | Free cholesterol in VLDL (UKB data field 23420) | 88,329 European ancestry individuals | T | 0.0746244 | 7E-45 | 44.155 | rs58542926 | 0.125676 | free cholesterol in VLDL measurement (EFO:0022276) |
PMID:36764567 |
GWAS854957_H | GCST90269516 | Total free cholesterol levels (UKB data field 23419) | 88,329 European ancestry individuals | T | 0.0746244 | 3E-34 | 33.523 | rs58542926 | 0.107465 | free cholesterol measurement (EFO:0008591) |
PMID:36764567 |
GWAS856800_H | GCST90269518 | Free cholesterol in LDL (UKB data field 23421) | 88,329 European ancestry individuals | T | 0.0746244 | 1E-19 | 19 | rs58542926 | 0.0809403 | free cholesterol in LDL measurement (EFO:0022266) |
PMID:36764567 |
GWAS862737_H | GCST90269536 | Apolipoprotein B levels (UKB data field 23439) | 88,329 European ancestry individuals | T | 0.0746244 | 6E-36 | 35.222 | rs58542926 | 0.112712 | apolipoprotein B measurement (EFO:0004615) |
PMID:36764567 |
GWAS862745_H | GCST90269540 | Degree of unsaturation (UKB data field 23443) | 88,268 European ancestry individuals | T | 0.0746023 | 7E-15 | 14.155 | rs58542926 | 0.066785 | degree of unsaturation measurement (EFO:0022261) |
PMID:36764567 |
GWAS863584_H | GCST90269538 | Apolipoprotein B to apolipoprotein A1 ratio (UKB data field 23441) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-21 | 20.699 | rs58542926 | 0.0844381 | apolipoprotein B to apolipoprotein A1 ratio (EFO:0021897) |
PMID:36764567 |
GWAS865602_H | GCST90269526 | Concentration of LDL particles (UKB data field 23429) | 88,329 European ancestry individuals | T | 0.0746244 | 8E-35 | 34.097 | rs58542926 | 0.110999 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36764567 |
GWAS866094_H | GCST90269622 | Phospholipids in IDL (UKB data field 23525) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-22 | 21.699 | rs58542926 | 0.0847908 | phospholipids in IDL measurement (EFO:0022164) |
PMID:36764567 |
GWAS866096_H | GCST90269623 | Cholesterol in IDL (UKB data field 23526) | 88,329 European ancestry individuals | T | 0.0746244 | 1E-20 | 20 | rs58542926 | 0.0813429 | cholesterol in IDL measurement (EFO:0021899) |
PMID:36764567 |
GWAS866205_H | GCST90269670 | Total lipids in small HDL (UKB data field 23573) | 88,329 European ancestry individuals | T | 0.0746244 | 8E-22 | 21.097 | rs58542926 | 0.0859907 | total lipids in small HDL measurement (EFO:0022311) |
PMID:36764567 |
GWAS866208_H | GCST90269673 | Cholesteryl esters in small HDL (UKB data field 23576) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-14 | 13.699 | rs58542926 | 0.0690461 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS866454_H | GCST90269637 | Cholesterol in medium LDL (UKB data field 23540) | 88,329 European ancestry individuals | T | 0.0746244 | 1E-33 | 33 | rs58542926 | 0.109156 | cholesterol in medium LDL measurement (EFO:0022224) |
PMID:36764567 |
GWAS866459_H | GCST90271622 | Nonalcoholic fatty liver disease | 691,479 European ancestry, African American or Afro-Caribbean, East Asian ancestry, Hispanic or Latin American, South Asian ancestry individuals | T | 0.07 | 1E-114 | 114 | rs58542926 | 22.76 | non-alcoholic fatty liver disease (EFO:0003095) |
PMID:37709864 |
GWAS866929_H | GCST90269588 | Cholesterol in very large VLDL (UKB data field 23491) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-42 | 41.699 | rs58542926 | 0.120325 | cholesterol in very large VLDL measurement (EFO:0022230) |
PMID:36764567 |
GWAS867894_H | GCST90269624 | Cholesteryl esters in IDL (UKB data field 23527) | 88,329 European ancestry individuals | T | 0.0746244 | 3E-22 | 21.523 | rs58542926 | 0.0846161 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS868496_H | GCST90269625 | Free cholesterol in IDL (UKB data field 23528) | 88,329 European ancestry individuals | T | 0.0746244 | 8E-16 | 15.097 | rs58542926 | 0.0704409 | free cholesterol in IDL measurement (EFO:0022181) |
PMID:36764567 |
GWAS868578_H | GCST90269639 | Free cholesterol in medium LDL (UKB data field 23542) | 88,329 European ancestry individuals | T | 0.0746244 | 3E-21 | 20.523 | rs58542926 | 0.085285 | free cholesterol in medium LDL measurement (EFO:0022268) |
PMID:36764567 |
GWAS868753_H | GCST90269607 | Total lipids in small VLDL (UKB data field 23510) | 88,329 European ancestry individuals | T | 0.0746244 | 3E-36 | 35.523 | rs58542926 | 0.112155 | total lipids in small VLDL (EFO:0022148) |
PMID:36764567 |
None Available | GCST90269671 | Phospholipids in small HDL (UKB data field 23574) | 88,329 European ancestry individuals | T | 0.0746244 | 1E-20 | 20 | rs58542926 | 0.0828801 | phospholipids in small HDL measurement (EFO:0022296) |
PMID:36764567 |
GWAS869092_H | GCST90269621 | Total lipids in IDL (UKB data field 23524) | 88,329 European ancestry individuals | T | 0.0746244 | 4E-23 | 22.398 | rs58542926 | 0.0865347 | total lipids in IDL (EFO:0022161) |
PMID:36764567 |
GWAS869502_H | GCST90269672 | Cholesterol in small HDL (UKB data field 23575) | 88,329 European ancestry individuals | T | 0.0746244 | 1E-16 | 16 | rs58542926 | 0.0743357 | cholesterol in small HDL measurement (EFO:0022226) |
PMID:36764567 |
GWAS869870_H | GCST90269606 | Concentration of small VLDL particles (UKB data field 23509) | 88,329 European ancestry individuals | T | 0.0746244 | 6E-35 | 34.222 | rs58542926 | 0.109622 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:36764567 |
GWAS869989_H | GCST90269636 | Phospholipids in medium LDL (UKB data field 23539) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-33 | 32.699 | rs58542926 | 0.108818 | phospholipids in medium LDL measurement (EFO:0022183) |
PMID:36764567 |
None Available | GCST90269638 | Cholesteryl esters in medium LDL (UKB data field 23541) | 88,329 European ancestry individuals | T | 0.0746244 | 4E-37 | 36.398 | rs58542926 | 0.114987 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS870956_H | GCST90269514 | Cholesteryl esters in LDL (UKB data field 23417) | 88,329 European ancestry individuals | T | 0.0746244 | 8E-33 | 32.097 | rs58542926 | 0.107302 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS871149_H | GCST90269509 | Phospholipids in VLDL (UKB data field 23412) | 88,329 European ancestry individuals | T | 0.0746244 | 4E-43 | 42.398 | rs58542926 | 0.122628 | phospholipids in VLDL measurement (EFO:0022301) |
PMID:36764567 |
GWAS871504_H | GCST90269513 | Cholesteryl esters in VLDL (UKB data field 23416) | 88,329 European ancestry individuals | T | 0.0746244 | 3E-39 | 38.523 | rs58542926 | 0.118246 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS871884_H | GCST90269736 | Phospholipids to total lipids in medium HDL percentage (UKB data field 23639) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-11 | 10.699 | rs58542926 | 0.0581016 | phospholipids:total lipids ratio (EFO:0020946) |
PMID:36764567 |
GWAS873209_H | GCST90269512 | Total esterified cholesterol levels (UKB data field 23415) | 88,329 European ancestry individuals | T | 0.0746244 | 8E-26 | 25.097 | rs58542926 | 0.0916077 | esterified cholesterol measurement (EFO:0008589) |
PMID:36764567 |
GWAS874629_H | GCST90269510 | Phospholipids in LDL (UKB data field 23413) | 88,329 European ancestry individuals | T | 0.0746244 | 4E-29 | 28.398 | rs58542926 | 0.100892 | phospholipids in LDL measurement (EFO:0022294) |
PMID:36764567 |
GWAS880468_H | GCST90269524 | Total concentration of lipoprotein particles (UKB data field 23427) | 88,329 European ancestry individuals | T | 0.0746244 | 7E-12 | 11.155 | rs58542926 | 0.0581351 | lipoprotein measurement (EFO:0004732) |
PMID:36764567 |
GWAS882606_H | GCST90269525 | Concentration of VLDL particles (UKB data field 23428) | 88,329 European ancestry individuals | T | 0.0746244 | 8E-41 | 40.097 | rs58542926 | 0.119745 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:36764567 |
GWAS883185_H | GCST90269543 | Polyunsaturated fatty acids levels (UKB data field 23446) | 88,268 European ancestry individuals | T | 0.0746023 | 2E-63 | 62.699 | rs58542926 | 0.147359 | polyunsaturated fatty acid measurement (EFO:0010733) |
PMID:36764567 |
GWAS883200_H | GCST90269541 | Omega-3 fatty acids levels (UKB data field 23444) | 88,268 European ancestry individuals | T | 0.0746023 | 2E-85 | 84.699 | rs58542926 | 0.170049 | omega-3 polyunsaturated fatty acid measurement (EFO:0010119) |
PMID:36764567 |
GWAS884141_H | GCST90269542 | Omega-6 fatty acids levels (UKB data field 23445) | 88,268 European ancestry individuals | T | 0.0746023 | 3E-44 | 43.523 | rs58542926 | 0.12261 | omega-6 polyunsaturated fatty acid measurement (EFO:0005680) |
PMID:36764567 |
GWAS886598_H | GCST90269605 | Triglycerides in medium VLDL (UKB data field 23508) | 88,329 European ancestry individuals | T | 0.0746244 | 5E-47 | 46.302 | rs58542926 | 0.126248 | triglycerides in medium VLDL measurement (EFO:0022155) |
PMID:36764567 |
None Available | GCST90269635 | Total lipids in medium LDL (UKB data field 23538) | 88,329 European ancestry individuals | T | 0.0746244 | 3E-34 | 33.523 | rs58542926 | 0.110244 | total lipids in medium LDL (EFO:0022180) |
PMID:36764567 |
GWAS888071_H | GCST90269603 | Cholesteryl esters in medium VLDL (UKB data field 23506) | 88,329 European ancestry individuals | T | 0.0746244 | 4E-22 | 21.398 | rs58542926 | 0.086558 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS888079_H | GCST90269602 | Cholesterol in medium VLDL (UKB data field 23505) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-32 | 31.699 | rs58542926 | 0.106845 | cholesterol in medium VLDL measurement (EFO:0022225) |
PMID:36764567 |
GWAS888182_H | GCST90269632 | Free cholesterol in large LDL (UKB data field 23535) | 88,329 European ancestry individuals | T | 0.0746244 | 7E-19 | 18.155 | rs58542926 | 0.0787945 | free cholesterol in large LDL measurement (EFO:0022176) |
PMID:36764567 |
GWAS888384_H | GCST90269604 | Free cholesterol in medium VLDL (UKB data field 23507) | 88,329 European ancestry individuals | T | 0.0746244 | 6E-44 | 43.222 | rs58542926 | 0.125237 | free cholesterol in medium VLDL measurement (EFO:0022269) |
PMID:36764567 |
None Available | GCST90200078 | 1-myristoyl-2-arachidonoyl-GPC (14:0/20:4) levels | 8,264 European ancestry individuals | T | 0.0756786 | 1E-12 | 12 | rs58542926 | 0.202338 | 1-myristoyl-2-arachidonoyl-GPC (14:0/20:4) measurement (EFO:0800453) |
PMID:36635386 |
GWAS894811_H | GCST90269548 | Omega-3 fatty acids to total fatty acids percentage (UKB data field 23451) | 88,268 European ancestry individuals | T | 0.0746023 | 4E-53 | 52.398 | rs58542926 | 0.132835 | omega-3 polyunsaturated fatty acid measurement (EFO:0010119) |
PMID:36764567 |
None Available | GCST90269528 | Average diameter for VLDL particles (UKB data field 23431) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-30 | 29.699 | rs58542926 | 0.0970382 | very low density lipoprotein particle size measurement (EFO:0008594) |
PMID:36764567 |
GWAS895700_H | GCST90269594 | Phospholipids in large VLDL (UKB data field 23497) | 88,329 European ancestry individuals | T | 0.0746244 | 3E-37 | 36.523 | rs58542926 | 0.111371 | phospholipids in large VLDL measurement (EFO:0022169) |
PMID:36764567 |
GWAS895759_H | GCST90269595 | Cholesterol in large VLDL (UKB data field 23498) | 88,329 European ancestry individuals | T | 0.0746244 | 6E-45 | 44.222 | rs58542926 | 0.12418 | cholesterol in large VLDL measurement (EFO:0021902) |
PMID:36764567 |
GWAS896261_H | GCST90269596 | Cholesteryl esters in large VLDL (UKB data field 23499) | 88,329 European ancestry individuals | T | 0.0746244 | 8E-47 | 46.097 | rs58542926 | 0.128081 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
None Available | GCST90269593 | Total lipids in large VLDL (UKB data field 23496) | 88,329 European ancestry individuals | T | 0.0746244 | 8E-43 | 42.097 | rs58542926 | 0.119824 | total lipids in large VLDL (EFO:0022175) |
PMID:36764567 |
GWAS897044_H | GCST90269597 | Free cholesterol in large VLDL (UKB data field 23500) | 88,329 European ancestry individuals | T | 0.0746244 | 7E-41 | 40.155 | rs58542926 | 0.117097 | free cholesterol in large VLDL measurement (EFO:0022265) |
PMID:36764567 |
GWAS898734_H | GCST90269598 | Triglycerides in large VLDL (UKB data field 23501) | 88,329 European ancestry individuals | T | 0.0746244 | 5E-42 | 41.302 | rs58542926 | 0.118081 | triglycerides in large VLDL measurement (EFO:0022178) |
PMID:36764567 |
GWAS899298_H | GCST90269644 | Cholesterol in small LDL (UKB data field 23547) | 88,329 European ancestry individuals | T | 0.0746244 | 6E-34 | 33.222 | rs58542926 | 0.109697 | cholesterol in small LDL measurement (EFO:0022227) |
PMID:36764567 |
GWAS899849_H | GCST90269669 | Concentration of small HDL particles (UKB data field 23572) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-20 | 19.699 | rs58542926 | 0.0833533 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:36764567 |
GWAS900012_H | GCST90269600 | Total lipids in medium VLDL (UKB data field 23503) | 88,329 European ancestry individuals | T | 0.0746244 | 3E-52 | 51.523 | rs58542926 | 0.136057 | total lipids in medium VLDL (EFO:0022153) |
PMID:36764567 |
GWAS900255_H | GCST90269599 | Concentration of medium VLDL particles (UKB data field 23502) | 88,329 European ancestry individuals | T | 0.0746244 | 7E-49 | 48.155 | rs58542926 | 0.132104 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:36764567 |
GWAS900540_H | GCST90269601 | Phospholipids in medium VLDL (UKB data field 23504) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-47 | 46.699 | rs58542926 | 0.130166 | phospholipids in medium VLDL measurement (EFO:0022154) |
PMID:36764567 |
GWAS900733_H | GCST90269620 | Concentration of IDL particles (UKB data field 23523) | 88,329 European ancestry individuals | T | 0.0746244 | 1E-26 | 26 | rs58542926 | 0.0952985 | intermediate density lipoprotein measurement (EFO:0008595) |
PMID:36764567 |
None Available | GCST90269643 | Phospholipids in small LDL (UKB data field 23546) | 88,329 European ancestry individuals | T | 0.0746244 | 1E-25 | 25 | rs58542926 | 0.0942382 | phospholipids in small LDL measurement (EFO:0022297) |
PMID:36764567 |
GWAS901236_H | GCST90200109 | Linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] levels | 7,744 European ancestry individuals | T | 0.0745506 | 6E-12 | 11.222 | rs58542926 | 0.209338 | linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] measurement (EFO:0800500) |
PMID:36635386 |
GWAS902019_H | GCST90269642 | Total lipids in small LDL (UKB data field 23545) | 88,329 European ancestry individuals | T | 0.0746244 | 9E-34 | 33.046 | rs58542926 | 0.109277 | total lipids in small LDL (EFO:0022168) |
PMID:36764567 |
GWAS902172_H | GCST90269641 | Concentration of small LDL particles (UKB data field 23544) | 88,329 European ancestry individuals | T | 0.0746244 | 1E-31 | 31 | rs58542926 | 0.105685 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36764567 |
GWAS902228_H | GCST90269629 | Phospholipids in large LDL (UKB data field 23532) | 88,329 European ancestry individuals | T | 0.0746244 | 3E-26 | 25.523 | rs58542926 | 0.0949294 | phospholipids in large LDL measurement (EFO:0022174) |
PMID:36764567 |
GWAS902698_H | GCST90269592 | Concentration of large VLDL particles (UKB data field 23495) | 88,329 European ancestry individuals | T | 0.0746244 | 5E-40 | 39.302 | rs58542926 | 0.115536 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:36764567 |
GWAS902941_H | GCST90269521 | Total lipids in VLDL (UKB data field 23424) | 88,329 European ancestry individuals | T | 0.0746244 | 3E-43 | 42.523 | rs58542926 | 0.122004 | total lipids in VLDL measurement (EFO:0022314) |
PMID:36764567 |
GWAS903565_H | GCST90269589 | Cholesteryl esters in very large VLDL (UKB data field 23492) | 88,329 European ancestry individuals | T | 0.0746244 | 1E-44 | 44 | rs58542926 | 0.124695 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS903887_H | GCST90269608 | Phospholipids in small VLDL (UKB data field 23511) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-38 | 37.699 | rs58542926 | 0.116484 | phospholipids in small VLDL measurement (EFO:0022146) |
PMID:36764567 |
GWAS903940_H | GCST90269631 | Cholesteryl esters in large LDL (UKB data field 23534) | 88,329 European ancestry individuals | T | 0.0746244 | 3E-28 | 27.523 | rs58542926 | 0.0986739 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS903954_H | GCST90269628 | Total lipids in large LDL (UKB data field 23531) | 88,329 European ancestry individuals | T | 0.0746244 | 5E-27 | 26.302 | rs58542926 | 0.096297 | total lipids in large LDL (EFO:0022163) |
PMID:36764567 |
GWAS904012_H | GCST90269645 | Cholesteryl esters in small LDL (UKB data field 23548) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-39 | 38.699 | rs58542926 | 0.118424 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
None Available | GCST90269611 | Free cholesterol in small VLDL (UKB data field 23514) | 88,329 European ancestry individuals | T | 0.0746244 | 8E-35 | 34.097 | rs58542926 | 0.11106 | free cholesterol in small VLDL measurement (EFO:0022272) |
PMID:36764567 |
GWAS904364_H | GCST90269556 | Omega-6 fatty acids to omega-3 fatty acids ratio (UKB data field 23459) | 88,268 European ancestry individuals | T | 0.0746023 | 8E-62 | 61.097 | rs58542926 | 0.143978 | omega-6:omega-3 polyunsaturated fatty acid ratio (EFO:0010732) |
PMID:36764567 |
None Available | GCST90269522 | Total lipids in LDL (UKB data field 23425) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-30 | 29.699 | rs58542926 | 0.10311 | total lipids in LDL measurement (EFO:0022308) |
PMID:36764567 |
None Available | GCST90269646 | Free cholesterol in small LDL (UKB data field 23549) | 88,329 European ancestry individuals | T | 0.0746244 | 1E-16 | 16 | rs58542926 | 0.0746264 | free cholesterol in small LDL measurement (EFO:0022271) |
PMID:36764567 |
GWAS904899_H | GCST90269534 | Phosphatidylcholines levels (UKB data field 23437) | 88,268 European ancestry individuals | T | 0.0746023 | 4E-21 | 20.398 | rs58542926 | 0.0795148 | phosphatidylcholine measurement (EFO:0010226) |
PMID:36764567 |
None Available | GCST90269520 | Total lipids in lipoprotein particles (UKB data field 23423) | 88,329 European ancestry individuals | T | 0.0746244 | 4E-43 | 42.398 | rs58542926 | 0.121962 | total lipids in lipoprotein particles measurement (EFO:0022309) |
PMID:36764567 |
GWAS905795_H | GCST90269609 | Cholesterol in small VLDL (UKB data field 23512) | 88,329 European ancestry individuals | T | 0.0746244 | 8E-31 | 30.097 | rs58542926 | 0.104022 | cholesterol in small VLDL measurement (EFO:0022228) |
PMID:36764567 |
GWAS905862_H | GCST90269630 | Cholesterol in large LDL (UKB data field 23533) | 88,329 European ancestry individuals | T | 0.0746244 | 7E-26 | 25.155 | rs58542926 | 0.0938924 | cholesterol in large LDL measurement (EFO:0021901) |
PMID:36764567 |
GWAS905959_H | GCST90269627 | Concentration of large LDL particles (UKB data field 23530) | 88,329 European ancestry individuals | T | 0.0746244 | 1E-35 | 35 | rs58542926 | 0.112044 | concentration of large LDL particles measurement (EFO:0022160) |
PMID:36764567 |
None Available | GCST90269535 | Sphingomyelins levels (UKB data field 23438) | 88,268 European ancestry individuals | T | 0.0746023 | 1E-13 | 13 | rs58542926 | 0.0629196 | sphingomyelin measurement (EFO:0010118) |
PMID:36764567 |
GWAS906391_H | GCST90269610 | Cholesteryl esters in small VLDL (UKB data field 23513) | 88,329 European ancestry individuals | T | 0.0746244 | 7E-28 | 27.155 | rs58542926 | 0.0985766 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS906511_H | GCST90432139 | ICD10 K70: Liver fibrosis and cirrhosis | 116,382 European ancestry cases, 213,325 European ancestry controls | ? | NR | 5E-10 | 9.302 | rs58542926 | 1.45 | cirrhosis of liver (EFO:0001422) |
PMID:37965154 |
GWAS907074_H | GCST90269726 | Phospholipids to total lipids in very large HDL percentage (UKB data field 23629) | 88,307 European ancestry individuals | T | 0.0746317 | 5E-11 | 10.302 | rs58542926 | 0.0547695 | phospholipids:total lipids ratio (EFO:0020946) |
PMID:36764567 |
None Available | GCST90269722 | Cholesterol to total lipids in small LDL percentage (UKB data field 23625) | 88,329 European ancestry individuals | T | 0.0746244 | 8E-16 | 15.097 | rs58542926 | 0.0725835 | cholesterol to total lipids in small LDL percentage (EFO:0022241) |
PMID:36764567 |
GWAS908115_H | GCST90269674 | Free cholesterol in small HDL (UKB data field 23577) | 88,329 European ancestry individuals | T | 0.0746244 | 6E-19 | 18.222 | rs58542926 | 0.0782496 | free cholesterol in small HDL measurement (EFO:0022270) |
PMID:36764567 |
None Available | GCST90269713 | Cholesteryl esters to total lipids in large LDL percentage (UKB data field 23616) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-20 | 19.699 | rs58542926 | 0.0832656 | cholesteryl esters to total lipids in large LDL percentage (EFO:0022249) |
PMID:36764567 |
GWAS910758_H | GCST90269723 | Cholesteryl esters to total lipids in small LDL percentage (UKB data field 23626) | 88,329 European ancestry individuals | T | 0.0746244 | 2E-36 | 35.699 | rs58542926 | 0.113563 | cholesteryl esters to total lipids in small LDL percentage (EFO:0022255) |
PMID:36764567 |
GWAS933197_H | GCST007515 | Type 2 diabetes | 48,286 European ancestry cases, 250,671 European ancestry controls, 33,126 African American, East Asian, Hispanic/Latino or South Asian cases, 120,161 African American, East Asian, Hispanic/Latino or South Asian controls | T | 0.0755 | 5E-12 | 11.302 | rs58542926 | 1.07 | PMID:29632382 | |
None Available | GCST007518 | Type 2 diabetes (adjusted for BMI) | up to 48,286 European ancestry cases, up to 250,671 European ancestry controls | T | 0.079 | 1E-12 | 12 | rs58542926 | 1.09 | PMID:29632382 | |
GWAS934615_H | GCST007516 | Type 2 diabetes (adjusted for BMI) | 48,286 European ancestry cases, 250,671 European ancestry controls, 33,126 African American, East Asian, Hispanic/Latino or South Asian cases, 120,161 African American, East Asian, Hispanic/Latino or South Asian controls | T | 0.0755 | 3E-15 | 14.523 | rs58542926 | 1.09 | PMID:29632382 | |
None Available | GCST007517 | Type 2 diabetes | up to 48,286 European ancestry cases, up to 250,671 European ancestry controls | T | 0.079 | 2E-10 | 9.699 | rs58542926 | 1.09 | PMID:29632382 | |
GWAS963155_H | GCST007931 | Medication use (HMG CoA reductase inhibitors) | 73,475 European ancestry cases, 216,910 European ancestry controls | T | 0.074933 | 2E-31 | 30.699 | rs58542926 | 0.12420776 | HMG CoA reductase inhibitor use measurement (EFO:0009932) |
PMID:31015401 |
GWAS970090_H | GCST010417 | Liver fat content (MRI proton density fat fraction measure) | 14,440 European ancestry individuals | T | 0.926558 | 6E-37 | 36.222 | rs58542926 | 0.206 | liver fat measurement (EFO:0010821) liver disease biomarker (EFO:0006845) |
PMID:32247823 |
None Available | GCST010418 | Liver fibrosis and steatohepatitis severity (MRI cT1 measure) | 14,440 European ancestry individuals | T | 0.07 | 1E-8 | 8 | rs58542926 | 0.124 | liver fat measurement (EFO:0010821) liver disease biomarker (EFO:0006845) |
PMID:32247823 |
None Available | GCST011352 | Alanine aminotransferase levels | 76,081 European ancestry individuals, 127,395 Japanese ancestry individuals | ? | NR | 1E-13 | 13 | rs58542926 | 0.0496 | serum alanine aminotransferase measurement (EFO:0004735) |
PMID:33339817 |
GWAS982187_H | GCST011586 | Cirrhosis (multi-trait analysis) | 4,829 European, African, Asian and unknown ancestry cases, 72,705 European, African, Asian and unknown ancestry controls, 362,539 European, African, Asian and unknown ancestry individuals with ALT measurements | T | 0.07 | 3E-83 | 82.523 | rs58542926 | N/A | cirrhosis of liver (EFO:0001422) |
PMID:33310085 |
GWAS984899_H | GCST90104006 | Familial combined hyperlipidemia defined by Consensus criteria | 39,961 British ancestry cases, 309,261 British ancestry controls | C | 0.924658 | 4E-42 | 41.398 | rs58542926 | 0.206379 | PMID:34906840 | |
None Available | GCST90104007 | Familial combined hyperlipidemia defined by Mexico criteria | 5,153 British ancestry cases, 344,069 British ancestry controls | C | 0.924658 | 2E-13 | 12.699 | rs58542926 | 0.30477 | PMID:34906840 | |
GWAS985919_H | GCST011345 | Triglyceride levels | 76,081 European ancestry individuals, 127,395 Japanese ancestry individuals | ? | NR | 3E-32 | 31.523 | rs58542926 | 0.0823 | triglyceride measurement (EFO:0004530) |
PMID:33339817 |
GWAS994971_H | GCST90129602 | Chronic elevation of alanine aminotransferase (cALT) levels | 95,472 European ancestry cases, 68,725 European ancestry controls | T | 0.075 | 2E-59 | 58.699 | rs58542926 | 0.222 | serum alanine aminotransferase measurement (EFO:0004735) |
PMID:35654975 |
GWAS996078_H | GCST90019521 | Total bilirubin levels | 341,077 European ancestry individuals, 5,978 African ancestry individuals, 7,313 South Asian ancestry individuals | T | NR | 5E-19 | 18.302 | rs58542926 | 0.0402 | bilirubin measurement (EFO:0004570) |
PMID:33462484 |
GWAS997537_H | GCST90104003 | Familial combined hyperlipidemia defined by Brunzell criteria | 3,838 British ancestry cases, 345,384 British ancestry controls | C | 0.924658 | 5E-15 | 14.302 | rs58542926 | 0.379227 | PMID:34906840 | |
GWAS998134_H | GCST90092883 | LDL cholesterol levels | 115,082 European ancestry individuals | C | 0.925601 | 6E-39 | 38.222 | rs58542926 | 0.102066 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS998367_H | GCST90104004 | Familial combined hyperlipidemia defined by Goldstein criteria | 1,688 British ancestry cases, 347,534 British ancestry controls | C | 0.924658 | 9E-11 | 10.046 | rs58542926 | 0.485627 | PMID:34906840 | |
GWAS998563_H | GCST90104005 | Familial combined hyperlipidemia defined by Dutch criteria | 17,485 British ancestry cases, 331,737 British ancestry controls | C | 0.924658 | 5E-41 | 40.302 | rs58542926 | 0.305585 | PMID:34906840 | |
GWAS999305_H | GCST90129601 | Chronic elevation of alanine aminotransferase (cALT) levels | 95,472 European ancestry cases, 68,725 European ancestry controls, 23,977 African American cases, 13,387 African American controls, 7,650 Hispanic cases, 7,468 Hispanic controls, 1,088 Asian ancestry cases, 828 Asian ancestry controls | T | 0.07 | 7E-62 | 61.155 | rs58542926 | 0.209 | serum alanine aminotransferase measurement (EFO:0004735) |
PMID:35654975 |
None Available | GCST90444202 | Type 2 diabetes | 51,256 African, African American, East Asian, South Asian, European, Middle Eastern, admixed American, other or other admixed ancestry cases, 370,487 African, African American, East Asian, South Asian, European, Middle Eastern, admixed American, other or other admixed ancestry controls | C | 0.928618 | 9E-16 | 15.046 | rs58542926 | 0.1197 | PMID:39379762 | |
GWAS999492_H | GCST90092982 | Sphingomyelin levels | 115,006 European ancestry individuals | C | 0.925621 | 2E-18 | 17.699 | rs58542926 | 0.0645666 | sphingomyelin measurement (EFO:0010118) |
PMID:35213538 |
GWAS999566_H | GCST90092994 | Degree of unsaturation | 115,006 European ancestry individuals | C | 0.925621 | 6E-18 | 17.222 | rs58542926 | 0.0644474 | fatty acid measurement (EFO:0005110) |
PMID:35213538 |
GWAS999624_H | GCST90020025 | Waist-to-hip ratio adjusted for BMI | 219,872 British ancestry women | T | NR | 4E-8 | 7.398 | rs58542926 | 0.0293826 | BMI-adjusted waist-hip ratio (EFO:0007788) |
PMID:34021172 |
None Available | GCST90092985 | Total cholesterol levels | 115,082 European ancestry individuals | C | 0.925601 | 2E-38 | 37.699 | rs58542926 | 0.0986602 | total cholesterol measurement (EFO:0004574) |
PMID:35213538 |
GWAS999634_H | GCST90092939 | Polyunsaturated fatty acid levels | 115,006 European ancestry individuals | C | 0.925621 | 4E-89 | 88.398 | rs58542926 | 0.152986 | polyunsaturated fatty acid measurement (EFO:0010733) |
PMID:35213538 |
None Available | GCST90092859 | Cholesteryl esters to total lipids ratio in large LDL | 115,082 European ancestry individuals | C | 0.925601 | 3E-28 | 27.523 | rs58542926 | 0.0868203 | low density lipoprotein cholesterol measurement (EFO:0004611) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:35213538 |
GWAS999663_H | GCST90092860 | Free cholesterol levels in large LDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-24 | 23.699 | rs58542926 | 0.0786471 | free cholesterol measurement (EFO:0008591) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092948 | Free cholesterol levels in small HDL | 115,082 European ancestry individuals | C | 0.925601 | 1E-25 | 25 | rs58542926 | 0.0807326 | free cholesterol measurement (EFO:0008591) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS999723_H | GCST90092906 | Cholesteryl ester levels in medium LDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-49 | 48.699 | rs58542926 | 0.11632 | cholesteryl ester measurement (EFO:0010351) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092908 | Free cholesterol levels in medium LDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-27 | 26.699 | rs58542926 | 0.0849664 | free cholesterol measurement (EFO:0008591) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS999835_H | GCST90092809 | Apolipoprotein B levels | 115,082 European ancestry individuals | C | 0.925601 | 3E-48 | 47.523 | rs58542926 | 0.114534 | apolipoprotein B measurement (EFO:0004615) |
PMID:35213538 |
None Available | GCST90019526 | Vitamin D levels | 327,435 European ancestry individuals, 5,845 African ancestry individuals, 6,425 South Asian ancestry individuals | T | NR | 2E-22 | 21.699 | rs58542926 | 0.0448 | vitamin D measurement (EFO:0004631) |
PMID:33462484 |
GWAS999945_H | GCST90092858 | Cholesteryl ester levels in large LDL | 115,082 European ancestry individuals | C | 0.925601 | 9E-38 | 37.046 | rs58542926 | 0.0999904 | cholesteryl ester measurement (EFO:0010351) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092916 | Cholesterol levels in medium VLDL | 115,082 European ancestry individuals | C | 0.925601 | 3E-43 | 42.523 | rs58542926 | 0.108136 | total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1000066_H | GCST90092922 | Total lipid levels in medium VLDL | 115,082 European ancestry individuals | C | 0.925601 | 5E-72 | 71.302 | rs58542926 | 0.140114 | very low density lipoprotein cholesterol measurement (EFO:0008317) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS1000079_H | GCST90092997 | Cholesteryl ester levels in VLDL | 115,082 European ancestry individuals | C | 0.925601 | 3E-53 | 52.523 | rs58542926 | 0.120764 | cholesteryl ester measurement (EFO:0010351) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1000083_H | GCST90092996 | VLDL cholesterol levels | 115,082 European ancestry individuals | C | 0.925601 | 1E-58 | 58 | rs58542926 | 0.12676 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1000279_H | GCST90092918 | Cholesteryl ester levels in medium VLDL | 115,082 European ancestry individuals | C | 0.925601 | 6E-29 | 28.222 | rs58542926 | 0.0869938 | cholesteryl ester measurement (EFO:0010351) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1000291_H | GCST90092930 | Total cholesterol minus HDL-C levels | 115,082 European ancestry individuals | C | 0.925601 | 2E-46 | 45.699 | rs58542926 | 0.11174 | total cholesterol measurement (EFO:0004574) |
PMID:35213538 |
GWAS1000294_H | GCST90092926 | Triglyceride levels in medium VLDL | 115,082 European ancestry individuals | C | 0.925601 | 5E-66 | 65.302 | rs58542926 | 0.131015 | triglyceride measurement (EFO:0004530) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1000297_H | GCST90092931 | Omega-3 fatty acid levels | 115,006 European ancestry individuals | C | 0.925621 | 3E-116 | 115.523 | rs58542926 | 0.172929 | omega-3 polyunsaturated fatty acid measurement (EFO:0010119) |
PMID:35213538 |
GWAS1000302_H | GCST90092933 | Omega-6 fatty acid levels | 115,006 European ancestry individuals | C | 0.925621 | 1E-62 | 62 | rs58542926 | 0.1284 | omega-6 polyunsaturated fatty acid measurement (EFO:0005680) |
PMID:35213538 |
GWAS1000304_H | GCST90092932 | Ratio of omega-3 fatty acids to total fatty acids | 115,006 European ancestry individuals | C | 0.925621 | 2E-68 | 67.699 | rs58542926 | 0.132116 | fatty acid measurement (EFO:0005110) |
PMID:35213538 |
GWAS1000323_H | GCST90092958 | Cholesteryl ester levels in small LDL | 115,082 European ancestry individuals | C | 0.925601 | 6E-53 | 52.222 | rs58542926 | 0.120415 | cholesteryl ester measurement (EFO:0010351) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS1000333_H | GCST90092923 | Concentration of medium VLDL particles | 115,082 European ancestry individuals | C | 0.925601 | 2E-66 | 65.699 | rs58542926 | 0.134969 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1000378_H | GCST90092974 | Total lipid levels in small VLDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-50 | 49.699 | rs58542926 | 0.116036 | very low density lipoprotein cholesterol measurement (EFO:0008317) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS1000383_H | GCST90092975 | Concentration of small VLDL particles | 115,082 European ancestry individuals | C | 0.925601 | 2E-48 | 47.699 | rs58542926 | 0.113301 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1000451_H | GCST90093001 | Phospholipid levels in VLDL | 115,082 European ancestry individuals | C | 0.925601 | 9E-61 | 60.046 | rs58542926 | 0.127577 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS1000497_H | GCST90092817 | Ratio of docosahexaenoic acid to total fatty acid levels | 115,006 European ancestry individuals | C | 0.925621 | 9E-9 | 8.046 | rs58542926 | 0.0437276 | docosahexaenoic acid measurement (EFO:0007761) fatty acid measurement (EFO:0005110) |
PMID:35213538 |
None Available | GCST90092831 | Cholesterol levels in IDL | 115,082 European ancestry individuals | C | 0.925601 | 3E-27 | 26.523 | rs58542926 | 0.0819405 | total cholesterol measurement (EFO:0004574) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
None Available | GCST90092833 | Cholesteryl ester levels in IDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-29 | 28.699 | rs58542926 | 0.0854001 | cholesteryl ester measurement (EFO:0010351) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
GWAS1000519_H | GCST90092845 | Cholesterol to total lipids ratio in large HDL | 115,082 European ancestry individuals | C | 0.925601 | 1E-9 | 9 | rs58542926 | 0.0448329 | cholesterol:total lipids ratio (EFO:0020943) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS1000541_H | GCST90092864 | Phospholipid levels in large LDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-34 | 33.699 | rs58542926 | 0.0952514 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS1000568_H | GCST90092965 | Phospholipids to total lipids ratio in small LDL | 115,082 European ancestry individuals | C | 0.925601 | 5E-35 | 34.302 | rs58542926 | 0.0970243 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipids:total lipids ratio (EFO:0020946) |
PMID:35213538 |
GWAS1000609_H | GCST90092946 | Cholesteryl ester levels in small HDL | 115,082 European ancestry individuals | C | 0.925601 | 5E-18 | 17.302 | rs58542926 | 0.0683105 | cholesteryl ester measurement (EFO:0010351) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS1000624_H | GCST90295949 | Triglyceride to HDL cholesterol ratio | 402,398 European ancestry individuals | C | 0.9252 | 7E-74 | 73.155 | rs58542926 | 0.1084 | triglyceride:HDL cholesterol ratio (EFO:0007929) |
PMID:38200128 |
None Available | GCST90092876 | Phospholipid levels in large VLDL | 115,082 European ancestry individuals | C | 0.925601 | 3E-53 | 52.523 | rs58542926 | 0.116501 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS1000690_H | GCST90092991 | Total phospholipid levels in lipoprotein particles | 115,082 European ancestry individuals | C | 0.925601 | 2E-45 | 44.699 | rs58542926 | 0.105948 | lipoprotein measurement (EFO:0004732) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS1000692_H | GCST90092989 | Total lipid levels in lipoprotein particles | 115,082 European ancestry individuals | C | 0.925601 | 4E-60 | 59.398 | rs58542926 | 0.126461 | lipid measurement (EFO:0004529) lipoprotein measurement (EFO:0004732) |
PMID:35213538 |
GWAS1000728_H | GCST90093000 | Concentration of VLDL particles | 115,082 European ancestry individuals | C | 0.925601 | 2E-56 | 55.699 | rs58542926 | 0.123573 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1000736_H | GCST90029073 | Liver fat | 32,974 European ancestry individuals | T | NR | 3E-85 | 84.523 | rs58542926 | 0.289 | liver fat measurement (EFO:0010821) |
PMID:34957434 |
GWAS1000864_H | GCST90092872 | Free cholesterol levels in large VLDL | 115,082 European ancestry individuals | C | 0.925601 | 1E-57 | 57 | rs58542926 | 0.12166 | free cholesterol measurement (EFO:0008591) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1000946_H | GCST90092924 | Phospholipid levels in medium VLDL | 115,082 European ancestry individuals | C | 0.925601 | 8E-65 | 64.097 | rs58542926 | 0.133402 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS1000980_H | GCST90093003 | Triglyceride levels in VLDL | 115,082 European ancestry individuals | C | 0.925601 | 1E-50 | 50 | rs58542926 | 0.113266 | triglyceride measurement (EFO:0004530) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1001114_H | GCST90092855 | Triglycerides to total lipids ratio in large HDL | 115,082 European ancestry individuals | C | 0.925601 | 4E-10 | 9.398 | rs58542926 | 0.0462852 | triglycerides:total lipids ratio (EFO:0020947) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
None Available | GCST90092856 | Cholesterol levels in large LDL | 115,082 European ancestry individuals | C | 0.925601 | 3E-34 | 33.523 | rs58542926 | 0.0948131 | total cholesterol measurement (EFO:0004574) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS1001133_H | GCST90024271 | Phosphatidylcholine (18:1_20:3) levels | 4,492 European ancestry individuals | T | NR | 0.000003 | 5.523 | rs58542926 | 0.189 | phosphatidylcholine measurement (EFO:0010226) |
PMID:35668104 |
None Available | GCST90092944 | Cholesterol levels in small HDL | 115,082 European ancestry individuals | C | 0.925601 | 3E-21 | 20.523 | rs58542926 | 0.0745835 | total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS1001257_H | GCST90093020 | Free cholesterol levels in very large VLDL | 115,082 European ancestry individuals | C | 0.925601 | 3E-54 | 53.523 | rs58542926 | 0.117996 | free cholesterol measurement (EFO:0008591) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1001499_H | GCST90092962 | Total lipid levels in small LDL | 115,082 European ancestry individuals | C | 0.925601 | 1E-45 | 45 | rs58542926 | 0.111197 | low density lipoprotein cholesterol measurement (EFO:0004611) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS1001533_H | GCST90092943 | Remnant cholesterol (non-HDL, non-LDL -cholesterol) | 115,082 European ancestry individuals | C | 0.925601 | 1E-51 | 51 | rs58542926 | 0.118025 | remnant cholesterol measurement (EFO:0010815) |
PMID:35213538 |
None Available | GCST90093016 | Cholesterol levels in very large VLDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-59 | 58.699 | rs58542926 | 0.124855 | total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
None Available | GCST90092950 | Total lipid levels in small HDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-29 | 28.699 | rs58542926 | 0.0884748 | lipid measurement (EFO:0004529) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS1001792_H | GCST90092870 | Cholesteryl ester levels in large VLDL | 115,082 European ancestry individuals | C | 0.925601 | 9E-65 | 64.046 | rs58542926 | 0.13194 | cholesteryl ester measurement (EFO:0010351) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1001811_H | GCST90092884 | Cholesteryl ester levels in LDL | 115,082 European ancestry individuals | C | 0.925601 | 9E-44 | 43.046 | rs58542926 | 0.108695 | cholesteryl ester measurement (EFO:0010351) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS1001815_H | GCST90092885 | Free cholesterol levels in LDL | 115,082 European ancestry individuals | C | 0.925601 | 3E-25 | 24.523 | rs58542926 | 0.0806667 | free cholesterol measurement (EFO:0008591) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092952 | Phospholipid levels in small HDL | 115,082 European ancestry individuals | C | 0.925601 | 3E-28 | 27.523 | rs58542926 | 0.0859811 | phospholipid measurement (EFO:0004639) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS1001862_H | GCST90093018 | Cholesteryl ester levels in very large VLDL | 115,082 European ancestry individuals | C | 0.925601 | 9E-62 | 61.046 | rs58542926 | 0.128364 | cholesteryl ester measurement (EFO:0010351) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
None Available | GCST90093024 | Phospholipid levels in very large VLDL | 115,082 European ancestry individuals | C | 0.925601 | 1E-50 | 50 | rs58542926 | 0.113497 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS1002022_H | GCST90092868 | Cholesterol levels in large VLDL | 115,082 European ancestry individuals | C | 0.925601 | 9E-63 | 62.046 | rs58542926 | 0.128539 | total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1002089_H | GCST90092886 | Total lipid levels in LDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-40 | 39.699 | rs58542926 | 0.104254 | low density lipoprotein cholesterol measurement (EFO:0004611) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS1002148_H | GCST90093023 | Concentration of very large VLDL particles | 115,082 European ancestry individuals | C | 0.925601 | 4E-48 | 47.398 | rs58542926 | 0.110093 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1002153_H | GCST90093022 | Total lipid levels in very large VLDL | 115,082 European ancestry individuals | C | 0.925601 | 5E-50 | 49.302 | rs58542926 | 0.11249 | very low density lipoprotein cholesterol measurement (EFO:0008317) lipid measurement (EFO:0004529) |
PMID:35213538 |
None Available | GCST90090992 | Total triglycerides levels | 17,563 African American individuals, 23,077 Hispanics ancestry individuals, 2,381 East Asian ancestry individuals, 1,915 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 360 individuals, 22,898 European ancestry individuals | ? | NR | 1E-15 | 15 | rs58542926 | 0.142 | triglyceride measurement (EFO:0004530) |
PMID:32226016 |
GWAS1002292_H | GCST90092874 | Total lipid levels in large VLDL | 115,082 European ancestry individuals | C | 0.925601 | 1E-60 | 60 | rs58542926 | 0.124873 | very low density lipoprotein cholesterol measurement (EFO:0008317) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS1002313_H | GCST90092956 | Cholesterol levels in small LDL | 115,082 European ancestry individuals | C | 0.925601 | 3E-45 | 44.523 | rs58542926 | 0.110978 | total cholesterol measurement (EFO:0004574) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS1002331_H | GCST90092904 | Cholesterol levels in medium LDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-44 | 43.699 | rs58542926 | 0.110051 | total cholesterol measurement (EFO:0004574) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092951 | Concentration of small HDL particles | 115,082 European ancestry individuals | C | 0.925601 | 1E-26 | 26 | rs58542926 | 0.0843503 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
None Available | GCST90092816 | Docosahexaenoic acid levels | 115,006 European ancestry individuals | C | 0.925621 | 1E-57 | 57 | rs58542926 | 0.119759 | docosahexaenoic acid measurement (EFO:0007761) |
PMID:35213538 |
GWAS1002493_H | GCST90019523 | Triglyceride levels | 342,233 European ancestry individuals, 6,014 African ancestry individuals, 7,330 South Asian ancestry individuals | T | NR | 1E-134 | 134 | rs58542926 | 0.1113 | triglyceride measurement (EFO:0004530) |
PMID:33462484 |
GWAS1002500_H | GCST90092837 | Total lipid levels in IDL | 115,082 European ancestry individuals | C | 0.925601 | 7E-31 | 30.155 | rs58542926 | 0.0876817 | lipid measurement (EFO:0004529) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
None Available | GCST90092875 | Concentration of large VLDL particles | 115,082 European ancestry individuals | C | 0.925601 | 2E-56 | 55.699 | rs58542926 | 0.120146 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1002574_H | GCST90092957 | Cholesterol to total lipids ratio in small LDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-17 | 16.699 | rs58542926 | 0.0673009 | cholesterol:total lipids ratio (EFO:0020943) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092964 | Phospholipid levels in small LDL | 115,082 European ancestry individuals | C | 0.925601 | 8E-35 | 34.097 | rs58542926 | 0.0961566 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS1002611_H | GCST90092887 | Concentration of LDL particles | 115,082 European ancestry individuals | C | 0.925601 | 6E-47 | 46.222 | rs58542926 | 0.112887 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS1002621_H | GCST90092959 | Cholesteryl esters to total lipids ratio in small LDL | 115,082 European ancestry individuals | C | 0.925601 | 6E-48 | 47.222 | rs58542926 | 0.114281 | low density lipoprotein cholesterol measurement (EFO:0004611) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:35213538 |
None Available | GCST90092960 | Free cholesterol levels in small LDL | 115,082 European ancestry individuals | C | 0.925601 | 3E-21 | 20.523 | rs58542926 | 0.0740868 | free cholesterol measurement (EFO:0008591) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS1002718_H | GCST90092880 | Linoleic acid levels | 115,006 European ancestry individuals | C | 0.925621 | 5E-46 | 45.302 | rs58542926 | 0.110032 | linoleic acid measurement (EFO:0006807) |
PMID:35213538 |
GWAS1002733_H | GCST90092821 | Glycoprotein acetyls levels | 115,082 European ancestry individuals | C | 0.925601 | 3E-13 | 12.523 | rs58542926 | 0.056681 | glycoprotein measurement (EFO:0004555) |
PMID:35213538 |
GWAS1002747_H | GCST90019512 | Low density lipoprotein cholesterol levels | 341,875 European ancestry individuals, 6,003 African ancestry individuals, 7,319 South Asian ancestry individuals | T | NR | 3E-228 | 227.523 | rs58542926 | 0.1453 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:33462484 |
None Available | GCST90096813 | PCSK9 levels | 10,186 European ancestry statin-free individuals | T | 0.0880837382093069 | 4E-8 | 7.398 | rs58542926 | 0.0482199 | proprotein convertase subtilisin/kexin type 9 measurement (EFO:0009312) |
PMID:34590679 |
GWAS1002770_H | GCST90092862 | Total lipid levels in large LDL | 115,082 European ancestry individuals | C | 0.925601 | 7E-36 | 35.155 | rs58542926 | 0.0972719 | low density lipoprotein cholesterol measurement (EFO:0004611) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS1002771_H | GCST90092863 | Concentration of large LDL particles | 115,082 European ancestry individuals | C | 0.925601 | 9E-49 | 48.046 | rs58542926 | 0.11484 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092888 | Phospholipid levels in LDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-38 | 37.699 | rs58542926 | 0.101624 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
None Available | GCST90092963 | Concentration of small LDL particles | 115,082 European ancestry individuals | C | 0.925601 | 4E-42 | 41.398 | rs58542926 | 0.106868 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092912 | Phospholipid levels in medium LDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-44 | 43.699 | rs58542926 | 0.109994 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS1002857_H | GCST90092911 | Concentration of medium LDL particles | 115,082 European ancestry individuals | C | 0.925601 | 1E-37 | 37 | rs58542926 | 0.101018 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS1002942_H | GCST90092972 | Free cholesterol levels in small VLDL | 115,082 European ancestry individuals | C | 0.925601 | 1E-46 | 46 | rs58542926 | 0.112646 | free cholesterol measurement (EFO:0008591) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1002949_H | GCST90092978 | Triglyceride levels in small VLDL | 115,082 European ancestry individuals | C | 0.925601 | 6E-38 | 37.222 | rs58542926 | 0.0977842 | triglyceride measurement (EFO:0004530) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1002976_H | GCST90092986 | Total esterified cholesterol levels | 115,082 European ancestry individuals | C | 0.925601 | 9E-35 | 34.046 | rs58542926 | 0.0932778 | esterified cholesterol measurement (EFO:0008589) |
PMID:35213538 |
GWAS1002980_H | GCST90092988 | Total free cholesterol levels | 115,082 European ancestry individuals | C | 0.925601 | 9E-47 | 46.046 | rs58542926 | 0.110237 | free cholesterol measurement (EFO:0008591) |
PMID:35213538 |
GWAS1003022_H | GCST90092003 | Alcohol-related hepatocellular carcinoma | 775 European ancestry cases, 1,332 European ancestry controls | T | 0.08 | 6E-10 | 9.222 | rs58542926 | 2.01 | hepatocellular carcinoma (EFO:0000182) |
PMID:34902334 |
GWAS1003101_H | GCST90092878 | Triglyceride levels in large VLDL | 115,082 European ancestry individuals | C | 0.925601 | 6E-60 | 59.222 | rs58542926 | 0.123566 | triglyceride measurement (EFO:0004530) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
None Available | GCST90092920 | Free cholesterol levels in medium VLDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-59 | 58.699 | rs58542926 | 0.127732 | free cholesterol measurement (EFO:0008591) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
None Available | GCST90295950 | Triglyceride to HDL cholesterol ratio | 185,749 European ancestry individuals | C | 0.9251 | 2E-59 | 58.699 | rs58542926 | 0.117 | triglyceride:HDL cholesterol ratio (EFO:0007929) |
PMID:38200128 |
None Available | GCST90092835 | Free cholesterol levels in IDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-20 | 19.699 | rs58542926 | 0.070486 | free cholesterol measurement (EFO:0008591) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
None Available | GCST90092838 | Concentration of IDL particles | 115,082 European ancestry individuals | C | 0.925601 | 1E-34 | 34 | rs58542926 | 0.0955365 | intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
None Available | GCST90092910 | Total lipid levels in medium LDL | 115,082 European ancestry individuals | C | 0.925601 | 1E-45 | 45 | rs58542926 | 0.111477 | low density lipoprotein cholesterol measurement (EFO:0004611) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS1003425_H | GCST90092968 | Cholesterol levels in small VLDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-41 | 40.699 | rs58542926 | 0.105835 | total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1003561_H | GCST90092847 | Cholesteryl esters to total lipids ratio in large HDL | 115,082 European ancestry individuals | C | 0.925601 | 9E-12 | 11.046 | rs58542926 | 0.0510754 | cholesteryl esters:total lipids ratio (EFO:0020944) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
None Available | GCST90092839 | Phospholipid levels in IDL | 115,082 European ancestry individuals | C | 0.925601 | 5E-30 | 29.302 | rs58542926 | 0.0862887 | phospholipid measurement (EFO:0004639) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
None Available | GCST90092814 | Clinical LDL cholesterol levels | 115,082 European ancestry individuals | C | 0.925601 | 7E-36 | 35.155 | rs58542926 | 0.0976272 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092992 | Total triglycerides levels | 115,082 European ancestry individuals | C | 0.925601 | 5E-47 | 46.302 | rs58542926 | 0.109371 | triglyceride measurement (EFO:0004530) |
PMID:35213538 |
GWAS1003819_H | GCST90029070 | C-reactive protein levels | 575,531 European ancestry individuals | T | NR | 4E-20 | 19.398 | rs58542926 | 0.036 | C-reactive protein measurement (EFO:0004458) |
PMID:35459240 |
GWAS1003898_H | GCST90092934 | Ratio of omega-6 fatty acids to omega-3 fatty acids | 115,006 European ancestry individuals | C | 0.925621 | 4E-81 | 80.398 | rs58542926 | 0.144499 | fatty acid measurement (EFO:0005110) |
PMID:35213538 |
GWAS1003979_H | GCST90302067 | Triglycerides in medium VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 2E-61 | 60.699 | rs58542926 | 0.1303 | triglycerides in medium VLDL measurement (EFO:0022155) |
PMID:38448586 |
GWAS1004003_H | GCST90302066 | Phospholipids to total lipids ratio in medium VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0717 | 6E-20 | 19.222 | rs58542926 | 0.0689 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946) |
PMID:38448586 |
GWAS1004007_H | GCST90302065 | Phospholipids in medium VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 8E-70 | 69.097 | rs58542926 | 0.139 | phospholipids in VLDL measurement (EFO:0022301) |
PMID:38448586 |
None Available | GCST90301968 | Glycoprotein acetylation | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 113,034 European ancestry individuals | T | 0.0721 | 1E-16 | 16 | rs58542926 | 0.0665 | glycoprotein measurement (EFO:0004555) |
PMID:38448586 |
GWAS1004242_H | GCST90302156 | Total lipids in very small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0718 | 4E-62 | 61.398 | rs58542926 | 0.129 | total lipids in very small VLDL measurement (EFO:0022156) |
PMID:38448586 |
None Available | GCST90302063 | Total lipids in medium VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 3E-70 | 69.523 | rs58542926 | 0.1394 | total lipids in medium VLDL (EFO:0022153) |
PMID:38448586 |
GWAS1004270_H | GCST90301988 | Linoleic acid (18:2) levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 3E-35 | 34.523 | rs58542926 | 0.0957 | linoleic acid measurement (EFO:0006807) |
PMID:38448586 |
GWAS1004368_H | GCST90092987 | Total fatty acid levels | 115,006 European ancestry individuals | C | 0.925621 | 2E-72 | 71.699 | rs58542926 | 0.139935 | fatty acid measurement (EFO:0005110) |
PMID:35213538 |
None Available | GCST90302077 | Saturated fatty acids | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0714 | 2E-48 | 47.699 | rs58542926 | 0.1158 | saturated fatty acids measurement (EFO:0022304) |
PMID:38448586 |
GWAS1004501_H | GCST90302158 | Phospholipids in very small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0717 | 4E-59 | 58.398 | rs58542926 | 0.1265 | phospholipids in VLDL measurement (EFO:0022301) |
PMID:38448586 |
GWAS1004504_H | GCST90302157 | Concentration of very small VLDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0718 | 7E-65 | 64.155 | rs58542926 | 0.132 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
None Available | GCST90302064 | Concentration of medium VLDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 2E-68 | 67.699 | rs58542926 | 0.1377 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS1004538_H | GCST90302061 | Free cholesterol in medium VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 7E-67 | 66.155 | rs58542926 | 0.1359 | free cholesterol in medium VLDL measurement (EFO:0022269) |
PMID:38448586 |
None Available | GCST90301985 | Triglycerides in IDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 1E-35 | 35 | rs58542926 | 0.0966 | triglycerides in IDL measurement (EFO:0022149) |
PMID:38448586 |
GWAS1004632_H | GCST90092998 | Free cholesterol levels in VLDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-62 | 61.699 | rs58542926 | 0.13003 | free cholesterol measurement (EFO:0008591) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1004764_H | GCST90302096 | Free cholesterol to total lipids ratio in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0719 | 9E-69 | 68.046 | rs58542926 | 0.133 | low density lipoprotein cholesterol measurement (EFO:0004611) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:38448586 |
None Available | GCST90302078 | Ratio of saturated fatty acids to total fatty acids | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0717 | 3E-14 | 13.523 | rs58542926 | 0.0577 | fatty acid measurement (EFO:0005110) |
PMID:38448586 |
GWAS1004782_H | GCST90302076 | Serum total triglyceride levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 6E-64 | 63.222 | rs58542926 | 0.1329 | triglyceride measurement (EFO:0004530) |
PMID:38448586 |
None Available | GCST90302160 | Triglycerides in very small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 3E-48 | 47.523 | rs58542926 | 0.1135 | triglycerides in very small VLDL measurement (EFO:0022144) |
PMID:38448586 |
None Available | GCST90302000 | Free cholesterol to total lipids ratio in large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0719 | 2E-18 | 17.699 | rs58542926 | 0.0669 | free cholesterol:total lipids ratio (EFO:0020945) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS1004917_H | GCST90092999 | Total lipid levels in VLDL | 115,082 European ancestry individuals | C | 0.925601 | 3E-61 | 60.523 | rs58542926 | 0.127241 | very low density lipoprotein cholesterol measurement (EFO:0008317) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS1005031_H | GCST90019505 | Direct bilirubin levels | 291,512 European ancestry individuals, 5,007 African ancestry individuals, 6,088 South Asian ancestry individuals | T | NR | 5E-43 | 42.302 | rs58542926 | 0.0667 | bilirubin measurement (EFO:0004570) |
PMID:33462484 |
GWAS1005041_H | GCST90302123 | Total cholesterol levels in VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0717 | 3E-80 | 79.523 | rs58542926 | 0.1479 | total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS1005053_H | GCST90302102 | Triglycerides to total lipids ratio in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 2E-9 | 8.699 | rs58542926 | 0.047 | triglycerides:total lipids ratio (EFO:0020947) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
None Available | GCST90302093 | Cholesterol esters in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 1E-33 | 33 | rs58542926 | 0.0947 | esterified cholesterol measurement (EFO:0008589) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
GWAS1005077_H | GCST90302053 | Triglycerides in medium LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 9E-25 | 24.046 | rs58542926 | 0.0806 | triglycerides in medium LDL measurement (EFO:0022322) |
PMID:38448586 |
GWAS1005115_H | GCST90302019 | Total Cholesterol in large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 5E-64 | 63.302 | rs58542926 | 0.133 | total cholesterol in large VLDL (EFO:0022177) |
PMID:38448586 |
GWAS1005165_H | GCST90301999 | Free cholesterol in large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0717 | 4E-12 | 11.398 | rs58542926 | 0.0525 | free cholesterol in large HDL measurement (EFO:0022157) |
PMID:38448586 |
None Available | GCST90302034 | Cholesteryl esters to total lipids ratio in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0718 | 2E-18 | 17.699 | rs58542926 | 0.066 | cholesteryl esters:total lipids ratio (EFO:0020944) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
None Available | GCST90019506 | Estimated glomerular filtration rate | 342,376 European ancestry individuals, 6,016 African ancestry individuals, 7,339 South Asian ancestry individuals | T | NR | 9E-12 | 11.046 | rs58542926 | 0.0307 | glomerular filtration rate (EFO:0005208) |
PMID:33462484 |
GWAS1005294_H | GCST90302124 | Mean diameter of VLDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 7E-37 | 36.155 | rs58542926 | 0.0996 | very low density lipoprotein particle size measurement (EFO:0008594) |
PMID:38448586 |
None Available | GCST90302152 | Cholesterol esters in very small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0719 | 5E-47 | 46.302 | rs58542926 | 0.1111 | very low density lipoprotein cholesterol measurement (EFO:0008317) esterified cholesterol measurement (EFO:0008589) |
PMID:38448586 |
GWAS1005308_H | GCST90302104 | Total cholesterol in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0718 | 4E-68 | 67.398 | rs58542926 | 0.1352 | total cholesterol in small VLDL (EFO:0022171) |
PMID:38448586 |
None Available | GCST90302103 | Sphingomyelins levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals | T | 0.0713 | 4E-20 | 19.398 | rs58542926 | 0.0739 | sphingomyelin measurement (EFO:0010118) |
PMID:38448586 |
None Available | GCST90302111 | Concentration of small VLDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 2E-66 | 65.699 | rs58542926 | 0.1347 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS1005354_H | GCST90302059 | Cholesterol esters in medium VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 2E-86 | 85.699 | rs58542926 | 0.1549 | cholesterol esters in medium VLDL measurement (EFO:0022182) |
PMID:38448586 |
None Available | GCST90302016 | Phospholipids to total lipids ratio in large LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0718 | 2E-29 | 28.699 | rs58542926 | 0.0858 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipids:total lipids ratio (EFO:0020946) |
PMID:38448586 |
GWAS1005548_H | GCST90019502 | Creatinine levels | 342,376 European ancestry individuals, 6,016 African ancestry individuals, 7,339 South Asian ancestry individuals | T | NR | 2E-12 | 11.699 | rs58542926 | 0.0317 | creatinine measurement (EFO:0004518) |
PMID:33462484 |
None Available | GCST90302155 | Free cholesterol to total lipids ratio in very small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0719 | 1E-9 | 9 | rs58542926 | 0.0452 | very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:38448586 |
GWAS1005589_H | GCST90302170 | Phospholipid levels in chylomicrons and extremely large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 6E-58 | 57.222 | rs58542926 | 0.1261 | chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipid measurement (EFO:0004639) |
PMID:38448586 |
None Available | GCST90302125 | Triglyceride levels in VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 1E-62 | 62 | rs58542926 | 0.1315 | triglyceride measurement (EFO:0004530) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
None Available | GCST90302110 | Total lipids in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0717 | 2E-68 | 67.699 | rs58542926 | 0.1363 | total lipids in small VLDL (EFO:0022148) |
PMID:38448586 |
GWAS1005625_H | GCST90302071 | Polyunsaturated fatty acids | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 1E-61 | 61 | rs58542926 | 0.1298 | polyunsaturated fatty acid measurement (EFO:0010733) |
PMID:38448586 |
GWAS1005688_H | GCST90302027 | Phospholipids in large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 1E-64 | 64 | rs58542926 | 0.1337 | phospholipids in VLDL measurement (EFO:0022301) |
PMID:38448586 |
None Available | GCST90302171 | Phospholipids to total lipids ratio in chylomicrons and extremely large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals | T | 0.0705 | 2E-12 | 11.699 | rs58542926 | 0.0582 | chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946) |
PMID:38448586 |
GWAS1005857_H | GCST90302172 | Triglyceride levels in chylomicrons and extremely large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 1E-56 | 56 | rs58542926 | 0.1248 | chylomicron measurement (EFO:0008596) triglyceride measurement (EFO:0004530) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS1005859_H | GCST90302169 | Concentration of chylomicrons and extremely large VLDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 4E-58 | 57.398 | rs58542926 | 0.1264 | chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS1006134_H | GCST90301973 | Triglyceride levels in HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 5E-31 | 30.302 | rs58542926 | 0.0911 | triglyceride measurement (EFO:0004530) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
None Available | GCST90301959 | Omega-3 fatty acids levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 3E-80 | 79.523 | rs58542926 | 0.1489 | omega-3 polyunsaturated fatty acid measurement (EFO:0010119) |
PMID:38448586 |
None Available | GCST90301950 | Conjugated linoleic acid | 70,413 Non-Finnish European ancestry individuals | T | 0.0743 | 5E-15 | 14.302 | rs58542926 | 0.0912 | linoleic acid measurement (EFO:0006807) |
PMID:38448586 |
None Available | GCST90301955 | Docosahexaenoic acid (22:6) levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 3E-53 | 52.523 | rs58542926 | 0.12 | docosahexaenoic acid measurement (EFO:0007761) |
PMID:38448586 |
GWAS1006242_H | GCST90302021 | Cholesterol esters in large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 6E-66 | 65.222 | rs58542926 | 0.135 | cholesterol esters in large VLDL measurement (EFO:0022170) |
PMID:38448586 |
None Available | GCST90301961 | Omega-6 fatty acids levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 1E-51 | 51 | rs58542926 | 0.1184 | omega-6 polyunsaturated fatty acid measurement (EFO:0005680) |
PMID:38448586 |
GWAS1006452_H | GCST90302084 | Free cholesterol to total lipids ratio in small HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.072 | 1E-17 | 17 | rs58542926 | 0.0634 | free cholesterol:total lipids ratio (EFO:0020945) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS1006489_H | GCST90275041 | Nonalcoholic fatty liver disease | 6,623 European ancestry cases, 26,318 European ancestry controls | T | NR | 7E-53 | 52.155 | rs58542926 | 1.4 | non-alcoholic fatty liver disease (EFO:0003095) |
PMID:37235137 |
GWAS1006499_H | GCST90275044 | Nonalcoholic fatty liver disease in lean individuals (BMI <25) | 810 European ancestry cases, 12,804 European ancestry controls | T | NR | 5E-14 | 13.302 | rs58542926 | 2.06 | non-alcoholic fatty liver disease (EFO:0003095) |
PMID:37235137 |
None Available | GCST90275047 | Nonalcoholic fatty liver disease in overweight individuals (25<=BMI<=30) | 3,069 European ancestry cases, 10,641 European ancestry controls | T | NR | 2E-28 | 27.699 | rs58542926 | 1.84 | non-alcoholic fatty liver disease (EFO:0003095) |
PMID:37235137 |
GWAS1006551_H | GCST90301995 | Total cholesterol in large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0717 | 3E-11 | 10.523 | rs58542926 | 0.0503 | total cholesterol change measurement (EFO:0007806) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS1006686_H | GCST90302090 | Triglycerides to total lipids ratio in small HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 4E-14 | 13.398 | rs58542926 | 0.0583 | triglycerides:total lipids ratio (EFO:0020947) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
None Available | GCST90302052 | Phospholipids to total lipids ratio in medium LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0717 | 2E-13 | 12.699 | rs58542926 | 0.056 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipids:total lipids ratio (EFO:0020946) |
PMID:38448586 |
GWAS1006731_H | GCST90302106 | Cholesterol esters in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0718 | 2E-65 | 64.699 | rs58542926 | 0.1323 | very low density lipoprotein cholesterol measurement (EFO:0008317) esterified cholesterol measurement (EFO:0008589) |
PMID:38448586 |
None Available | GCST90302055 | Monounsaturated fatty acids (16:1, 18:1) levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0714 | 2E-63 | 62.699 | rs58542926 | 0.1329 | fatty acid measurement (EFO:0005110) |
PMID:38448586 |
None Available | GCST90275050 | Nonalcoholic fatty liver disease in obese individuals (BMI>30) | 2,744 European ancestry cases, 2,873 European ancestry controls | T | NR | 5E-15 | 14.302 | rs58542926 | 1.76 | non-alcoholic fatty liver disease (EFO:0003095) |
PMID:37235137 |
None Available | GCST90301993 | Triglyceride levels in LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 8E-31 | 30.097 | rs58542926 | 0.0906 | triglyceride measurement (EFO:0004530) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
GWAS1006855_H | GCST90093015 | Triglycerides to total lipids ratio in very large HDL | 115,056 European ancestry individuals | C | 0.925593 | 3E-19 | 18.523 | rs58542926 | 0.0661756 | triglycerides:total lipids ratio (EFO:0020947) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS1006862_H | GCST90093026 | Triglyceride levels in very large VLDL | 115,082 European ancestry individuals | C | 0.925601 | 8E-44 | 43.097 | rs58542926 | 0.104411 | triglyceride measurement (EFO:0004530) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
None Available | GCST90302116 | Ratio of triglycerides to phosphoglycerides | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0714 | 1E-34 | 34 | rs58542926 | 0.0968 | triglyceride measurement (EFO:0004530) phospholipid measurement (EFO:0004639) |
PMID:38448586 |
None Available | GCST90302119 | Total phosphoglycerides levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 6E-36 | 35.222 | rs58542926 | 0.0983 | phosphoglycerides measurement (EFO:0022291) |
PMID:38448586 |
None Available | GCST90302089 | Triglycerides in small HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 7E-17 | 16.155 | rs58542926 | 0.0652 | triglycerides in small HDL measurement (EFO:0022158) |
PMID:38448586 |
None Available | GCST90302100 | Phospholipids to total lipids ratio in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0717 | 8E-22 | 21.097 | rs58542926 | 0.0729 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipids:total lipids ratio (EFO:0020946) |
PMID:38448586 |
None Available | GCST90302025 | Total lipids in large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 1E-62 | 62 | rs58542926 | 0.1315 | total lipids in large VLDL (EFO:0022175) |
PMID:38448586 |
None Available | GCST90092970 | Cholesteryl ester levels in small VLDL | 115,082 European ancestry individuals | C | 0.925601 | 1E-37 | 37 | rs58542926 | 0.100537 | cholesteryl ester measurement (EFO:0010351) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1007231_H | GCST90302118 | Total fatty acids | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0714 | 5E-67 | 66.302 | rs58542926 | 0.1366 | fatty acid measurement (EFO:0005110) |
PMID:38448586 |
GWAS1007233_H | GCST90302117 | Total cholines levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 8E-34 | 33.097 | rs58542926 | 0.095 | choline measurement (EFO:0010116) |
PMID:38448586 |
GWAS1007238_H | GCST90302138 | Total cholesterol in very large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 7E-58 | 57.155 | rs58542926 | 0.126 | total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS1007246_H | GCST90302113 | Phospholipids to total lipids ratio in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0717 | 1E-43 | 43 | rs58542926 | 0.1053 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946) |
PMID:38448586 |
GWAS1007247_H | GCST90302114 | Triglycerides in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 8E-57 | 56.097 | rs58542926 | 0.1249 | triglycerides in small VLDL measurement (EFO:0022145) |
PMID:38448586 |
GWAS1007276_H | GCST90302146 | Phospholipids in very large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 7E-59 | 58.155 | rs58542926 | 0.1273 | phospholipids in VLDL measurement (EFO:0022301) |
PMID:38448586 |
GWAS1007279_H | GCST90302148 | Triglycerides in very large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 7E-56 | 55.155 | rs58542926 | 0.1239 | triglycerides in very large VLDL measurement (EFO:0022325) |
PMID:38448586 |
None Available | GCST90302056 | Ratio of monounsaturated fatty acids to total fatty acids | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 6E-18 | 17.222 | rs58542926 | 0.0666 | fatty acid measurement (EFO:0005110) |
PMID:38448586 |
None Available | GCST90302026 | Concentration of large VLDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 4E-62 | 61.398 | rs58542926 | 0.1309 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS1007370_H | GCST90302032 | Total cholesterol to total lipids ratio in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0719 | 5E-16 | 15.302 | rs58542926 | 0.0608 | esterified cholesterol measurement (EFO:0008589) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS1007372_H | GCST90295951 | Triglyceride to HDL cholesterol ratio | 216,649 European ancestry individuals | C | 0.9252 | 7E-27 | 26.155 | rs58542926 | 0.074 | triglyceride:HDL cholesterol ratio (EFO:0007929) |
PMID:38200128 |
GWAS1007377_H | GCST90092976 | Phospholipid levels in small VLDL | 115,082 European ancestry individuals | C | 0.925601 | 2E-52 | 51.699 | rs58542926 | 0.119276 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS1007506_H | GCST90302140 | Cholesterol esters in very large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 8E-56 | 55.097 | rs58542926 | 0.1237 | very low density lipoprotein cholesterol measurement (EFO:0008317) esterified cholesterol measurement (EFO:0008589) |
PMID:38448586 |
GWAS1007523_H | GCST90302136 | Triglycerides in very large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 1E-11 | 11 | rs58542926 | 0.0526 | triglycerides in very large HDL measurement (EFO:0022324) |
PMID:38448586 |
None Available | GCST90302137 | Triglycerides to total lipids ratio in very large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0717 | 1E-15 | 15 | rs58542926 | 0.0627 | triglycerides:total lipids ratio (EFO:0020947) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS1007562_H | GCST90302145 | Concentration of very large VLDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 4E-57 | 56.398 | rs58542926 | 0.1253 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS1007563_H | GCST90301947 | Ratio of apolipoprotein B to apolipoprotein A1 levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 3E-57 | 56.523 | rs58542926 | 0.1252 | apolipoprotein A 1 measurement (EFO:0004614) apolipoprotein B measurement (EFO:0004615) |
PMID:38448586 |
None Available | GCST90302069 | Phosphatidylcholine and other choline levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0718 | 3E-36 | 35.523 | rs58542926 | 0.0976 | choline measurement (EFO:0010116) |
PMID:38448586 |
GWAS1007587_H | GCST90302057 | Total cholesterol in medium VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 1E-80 | 80 | rs58542926 | 0.1496 | total cholesterol in medium VLDL (EFO:0022162) |
PMID:38448586 |
None Available | GCST90301984 | Phospholipids to total lipids ratio in IDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0719 | 7E-45 | 44.155 | rs58542926 | 0.105 | phospholipids:total lipids ratio (EFO:0020946) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:38448586 |
None Available | GCST90302023 | Free cholesterol in large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 2E-59 | 58.699 | rs58542926 | 0.1279 | free cholesterol in large VLDL measurement (EFO:0022265) |
PMID:38448586 |
None Available | GCST90302029 | Triglycerides in large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 1E-60 | 60 | rs58542926 | 0.1292 | triglycerides in large VLDL measurement (EFO:0022178) |
PMID:38448586 |
None Available | GCST90019504 | Cystatin C levels | 342,399 European ancestry individuals, 6,015 African ancestry individuals, 7,338 South Asian ancestry individuals | T | NR | 4E-10 | 9.398 | rs58542926 | 0.0281 | cystatin C measurement (EFO:0004617) |
PMID:33462484 |
None Available | GCST90302162 | Total cholesterol levels in chylomicrons and extremely large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 1E-60 | 60 | rs58542926 | 0.1292 | chylomicron measurement (EFO:0008596) total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS1007837_H | GCST90302098 | Concentration of small LDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 3E-41 | 40.523 | rs58542926 | 0.1053 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
GWAS1007876_H | GCST90302074 | Remnant cholesterol (non-HDL, non-LDL -cholesterol) | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0717 | 2E-75 | 74.699 | rs58542926 | 0.1431 | remnant cholesterol measurement (EFO:0010815) |
PMID:38448586 |
None Available | GCST90302142 | Free cholesterol in very large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 4E-58 | 57.398 | rs58542926 | 0.1263 | free cholesterol in very large VLDL measurement (EFO:0022274) |
PMID:38448586 |
GWAS1008092_H | GCST90302144 | Total lipids in very large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 2E-57 | 56.699 | rs58542926 | 0.1258 | total lipids in very large VLDL measurement (EFO:0022313) |
PMID:38448586 |
None Available | GCST90302164 | Cholesteryl ester levels in chylomicrons and extremely large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 1E-64 | 64 | rs58542926 | 0.1334 | cholesteryl ester measurement (EFO:0010351) chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
None Available | GCST90302101 | Triglycerides in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 1E-44 | 44 | rs58542926 | 0.1101 | triglycerides in small LDL measurement (EFO:0022323) |
PMID:38448586 |
GWAS1008141_H | GCST90301946 | Apolipoprotein B levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0717 | 9E-76 | 75.046 | rs58542926 | 0.1439 | apolipoprotein B measurement (EFO:0004615) |
PMID:38448586 |
None Available | GCST90302166 | Free cholesterol levels in chylomicrons and extremely large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 1E-50 | 50 | rs58542926 | 0.1177 | free cholesterol measurement (EFO:0008591) chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS1008363_H | GCST90302168 | Total lipid levels in chylomicrons and extremely large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 2E-58 | 57.699 | rs58542926 | 0.1266 | chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) lipid measurement (EFO:0004529) |
PMID:38448586 |
None Available | GCST90302097 | Total lipids in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 5E-40 | 39.302 | rs58542926 | 0.1036 | total lipids in small LDL (EFO:0022168) |
PMID:38448586 |
None Available | GCST90278645 | Triglyceride levels | 92,615 Taiwanese ancestry individuals | ? | NR | 2E-28 | 27.699 | rs58542926 | N/A | triglyceride measurement (EFO:0004530) |
PMID:38116116 |
GWAS1009185_H | GCST90302041 | Triglycerides in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 5E-60 | 59.302 | rs58542926 | 0.1285 | triglycerides in medium HDL measurement (EFO:0022321) |
PMID:38448586 |
GWAS1010143_H | GCST90301998 | Cholesteryl esters to total lipids ratio in large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0719 | 6E-33 | 32.222 | rs58542926 | 0.0914 | cholesteryl esters:total lipids ratio (EFO:0020944) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS1010144_H | GCST90301997 | Cholesterol esters in large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0718 | 7E-11 | 10.155 | rs58542926 | 0.0494 | cholesterol esters in large HDL measurement (EFO:0022159) |
PMID:38448586 |
None Available | GCST90301996 | Total cholesterol to total lipids ratio in large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0719 | 8E-34 | 33.097 | rs58542926 | 0.0927 | cholesterol:total lipids ratio (EFO:0020943) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS1010152_H | GCST90302012 | Free cholesterol to total lipids ratio in large LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0717 | 9E-84 | 83.046 | rs58542926 | 0.1471 | low density lipoprotein cholesterol measurement (EFO:0004611) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:38448586 |
None Available | GCST90302045 | Cholesterol esters in medium LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 2E-34 | 33.699 | rs58542926 | 0.0958 | cholesterol esters in medium LDL measurement (EFO:0022186) |
PMID:38448586 |
None Available | GCST90301978 | Cholesteryl esters to total lipids ratio in IDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0718 | 1E-15 | 15 | rs58542926 | 0.0616 | cholesteryl esters:total lipids ratio (EFO:0020944) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:38448586 |
None Available | GCST90302048 | Free cholesterol to total lipids ratio in medium LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0716 | 1E-62 | 62 | rs58542926 | 0.126 | low density lipoprotein cholesterol measurement (EFO:0004611) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:38448586 |
GWAS1012287_H | GCST90302004 | Phospholipids to total lipids ratio in large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0719 | 2E-26 | 25.699 | rs58542926 | 0.0838 | phospholipids:total lipids ratio (EFO:0020946) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS1012292_H | GCST90302006 | Triglycerides to total lipids ratio in large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0718 | 8E-14 | 13.097 | rs58542926 | 0.0584 | triglycerides:total lipids ratio (EFO:0020947) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS1012859_H | GCST90270119 | Multi-trait sum score | 141,980 European ancestry males | ? | NR | 5E-20 | 19.302 | rs58542926 | N/A | complex trait (EFO:0010578) |
PMID:37277458 |
GWAS1012866_H | GCST90302042 | Triglycerides to total lipids ratio in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0717 | 5E-36 | 35.302 | rs58542926 | 0.0976 | triglycerides:total lipids ratio (EFO:0020947) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS1013128_H | GCST90302010 | Cholesteryl esters to total lipids ratio in large LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0715 | 7E-42 | 41.155 | rs58542926 | 0.1058 | low density lipoprotein cholesterol measurement (EFO:0004611) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:38448586 |
None Available | GCST90019497 | Aspartate aminotransferase levels | 341,246 European ancestry individuals, 5,982 African ancestry individuals, 7,313 South Asian ancestry individuals | T | NR | 1E-45 | 45 | rs58542926 | 0.064 | aspartate aminotransferase measurement (EFO:0004736) |
PMID:33462484 |
GWAS1013652_H | GCST90314551 | DPP7/VSIR protein level ratio | 43,509 European ancestry individuals | ? | NR | 9E-42 | 41.046 | rs58542926 | 0.175825 | blood protein measurement (EFO:0007937) |
PMID:38412862 |
GWAS1014466_H | GCST90019498 | Aspartate aminotransferase to alanine aminotransferase ratio | 341,165 European ancestry individuals, 5,981 African ancestry individuals, 7,309 South Asian ancestry individuals | T | NR | 7E-60 | 59.155 | rs58542926 | 0.0737 | aspartate aminotransferase to alanine aminotransferase ratio (EFO:0010934) |
PMID:33462484 |
GWAS1014733_H | GCST90016673 | Percent liver fat | 32,858 European ancestry individuals | ? | NR | 2E-116 | 115.699 | rs58542926 | 0.333 | liver fat measurement (EFO:0010821) |
PMID:34128465 |
GWAS1015311_H | GCST90019499 | C-reactive protein levels | 341,805 European ancestry individuals, 6,006 African ancestry individuals, 7,316 South Asian ancestry individuals | T | NR | 3E-18 | 17.523 | rs58542926 | 0.0393 | C-reactive protein measurement (EFO:0004458) |
PMID:33462484 |
None Available | GCST90019500 | Calcium levels | 313,387 European ancestry individuals, 5,576 African ancestry individuals, 6,696 South Asian ancestry individuals | T | NR | 1E-12 | 12 | rs58542926 | 0.0336 | calcium measurement (EFO:0004838) |
PMID:33462484 |
GWAS1017044_H | GCST90019501 | Total cholesterol levels | 342,508 European ancestry individuals, 6,014 African ancestry individuals, 7,336 South Asian ancestry individuals | T | NR | 6E-259 | 258.222 | rs58542926 | 0.1547 | total cholesterol measurement (EFO:0004574) |
PMID:33462484 |
GWAS1021201_H | GCST90314933 | GLB1/PCSK9 protein level ratio | 43,509 European ancestry individuals | ? | NR | 2E-88 | 87.699 | rs58542926 | 0.248732 | blood protein measurement (EFO:0007937) |
PMID:38412862 |
GWAS1021568_H | GCST90019492 | Alanine aminotransferase levels | 342,387 European ancestry individuals, 6,017 African ancestry individuals, 7,325 South Asian ancestry individuals | T | NR | 6E-86 | 85.222 | rs58542926 | 0.0886 | serum alanine aminotransferase measurement (EFO:0004735) |
PMID:33462484 |
GWAS1022902_H | GCST90019493 | Serum albumin levels | 313,032 European ancestry individuals, 5,573 African ancestry individuals, 6,687 South Asian ancestry individuals | T | NR | 3E-16 | 15.523 | rs58542926 | 0.0386 | serum albumin measurement (EFO:0004535) |
PMID:33462484 |
GWAS1024427_H | GCST90013405 | Liver enzyme levels (alanine transaminase) | 437,267 European ancestry individuals | C | 0.925238 | 2E-119 | 118.699 | rs58542926 | 0.01705 | serum alanine aminotransferase measurement (EFO:0004735) |
PMID:33972514 |
None Available | GCST90244007 | Triglyceride levels | 288,127 East Asian ancestry individuals | T | 0.0743 | 8E-47 | 46.097 | rs58542926 | 0.0825 | triglyceride measurement (EFO:0004530) |
PMID:36333282 |
None Available | GCST90060200 | Diacylglycerol_38:5_[M+H-H2O]1+ levels | 13,814 British ancestry individuals | T | NR | 4E-12 | 11.398 | rs58542926 | 0.107672 | diacylglycerol 38:5 measurement (EFO:0020067) |
PMID:34503513 |
GWAS1026965_H | GCST90019494 | Serum alkaline phosphatase levels | 342,535 European ancestry individuals, 6,019 African ancestry individuals, 7,337 South Asian ancestry individuals | T | NR | 7E-95 | 94.155 | rs58542926 | 0.0931 | alkaline phosphatase measurement (EFO:0004533) |
PMID:33462484 |
GWAS1026990_H | GCST90019496 | Apolipoprotein B levels | 340,860 European ancestry individuals, 5,962 African ancestry individuals, 7,275 South Asian ancestry individuals | T | NR | 1E-161 | 161 | rs58542926 | 0.1224 | apolipoprotein B measurement (EFO:0004615) |
PMID:33462484 |
None Available | GCST90103107 | Oleoyl-arachidonoyl-glycerol (18:1/20:4) [2] levels | 8,809 European ancestry individuals | T | NR | 7E-12 | 11.155 | rs58542926 | 0.196 | oleoyl-arachidonoyl-glycerol (18:1/20:4) [2] measurement (EFO:0800508) |
PMID:35050183 |
GWAS1029804_H | GCST90255382 | Minimum measurement of hepatic fat | 7,096 European ancestry individuals | ? | NR | 1E-7 | 7 | rs58542926 | 1.553 | liver fat measurement (EFO:0010821) |
PMID:36513072 |
None Available | GCST90255386 | Maximum measurement of hepatic fat | 2,814 African ancestry individuals, 7,096 European ancestry individuals, 113 Hispanic or Latin American individuals, 103 East Asian ancestry individuals, 84 South Asian ancestry individuals | ? | NR | 3E-14 | 13.523 | rs58542926 | 2.126 | liver fat measurement (EFO:0010821) |
PMID:36513072 |
GWAS1029808_H | GCST90255380 | Maximum measurement of hepatic fat | 7,096 European ancestry individuals | ? | NR | 2E-15 | 14.699 | rs58542926 | 2.529 | liver fat measurement (EFO:0010821) |
PMID:36513072 |
GWAS1029810_H | GCST90255381 | Median measurement of hepatic fat | 7,096 European ancestry individuals | ? | NR | 4E-13 | 12.398 | rs58542926 | 1.992 | liver fat measurement (EFO:0010821) |
PMID:36513072 |
GWAS1029812_H | GCST90255387 | Median measurement of hepatic fat | 2,814 African ancestry individuals, 7,096 European ancestry individuals, 113 Hispanic or Latin American individuals, 103 East Asian ancestry individuals, 84 South Asian ancestry individuals | ? | NR | 3E-12 | 11.523 | rs58542926 | 1.688 | liver fat measurement (EFO:0010821) |
PMID:36513072 |
None Available | GCST90255388 | Minimum measurement of hepatic fat | 2,814 African ancestry individuals, 7,096 European ancestry individuals, 113 Hispanic or Latin American individuals, 103 East Asian ancestry individuals, 84 South Asian ancestry individuals | ? | NR | 2E-7 | 6.699 | rs58542926 | 1.345 | liver fat measurement (EFO:0010821) |
PMID:36513072 |
GWAS1029885_H | GCST90179148 | Low-density lipoprotein levels (MTAG) | 361,194 European ancestry individuals | T | NR | 2E-96 | 95.699 | rs58542926 | 0.0548 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36376304 |
GWAS1029889_H | GCST90267352 | Liver proton density fat fraction | 33,235 European ancestry individuals | T | 0.07 | 4E-110 | 109.398 | rs58542926 | 22.29 | liver fat measurement (EFO:0010821) |
PMID:36402844 |
GWAS1029965_H | GCST90267367 | Body composition (MOSTest) | 33,588 European ancestry individuals | ? | NR | 2E-141 | 140.699 | rs58542926 | 25.32 | body composition measurement (EFO:0005106) |
PMID:36402844 |
GWAS1029978_H | GCST90239678 | Total cholesterol levels | 40,963 South Asian ancestry individuals | T | 0.0900638 | 1E-30 | 30 | rs58542926 | 0.154755 | total cholesterol measurement (EFO:0004574) |
PMID:34887591 |
GWAS1030765_H | GCST90244680 | Triglyceride levels in non-type 2 diabetes | 402,944 European ancestry individuals | ? | NR | 8E-159 | 158.097 | rs58542926 | N/A | triglyceride measurement (EFO:0004530) |
PMID:36269708 |
GWAS1031077_H | GCST90239655 | Low density lipoprotein cholesterol levels | 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals | ? | NR | 8E-403 | 402.097 | rs58542926 | N/A | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:34887591 |
GWAS1032071_H | GCST90133361 | Circulating docosahexaenoic acid levels | 114,999 European ancestry individuals | C | 0.93 | 6E-55 | 54.222 | rs58542926 | 0.119 | docosahexaenoic acid measurement (EFO:0007761) |
PMID:35692035 |
GWAS1032083_H | GCST90239661 | Triglyceride levels | 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals | ? | NR | 4E-413 | 412.398 | rs58542926 | N/A | triglyceride measurement (EFO:0004530) |
PMID:34887591 |
GWAS1032731_H | GCST90239610 | Triglyceride levels | 76,053 Taiwanese ancestry individuals | ? | NR | 3E-24 | 23.523 | rs58542926 | 6.39697 | triglyceride measurement (EFO:0004530) |
PMID:36329257 |
None Available | GCST90314428 | DCBLD2/PLA2G15 protein level ratio | 43,509 European ancestry individuals | ? | NR | 2E-50 | 49.699 | rs58542926 | 0.188944 | blood protein measurement (EFO:0007937) |
PMID:38412862 |
None Available | GCST009167 | Vitamin levels | up to 1,200 European ancestry individuals | ? | NR | 1E-8 | 8 | rs58542926 | N/A | vitamin measurement (EFO:0004729) alpha-tocopherol measurement (EFO:0007898) |
PMID:23696881 |
GWAS1036380_H | GCST90134521 | Triglyceride levels | 58,701 Korean ancestry individuals | T | NR | 4E-18 | 17.398 | rs58542926 | 6.56 | triglyceride measurement (EFO:0004530) |
PMID:35884923 |
GWAS1036930_H | GCST90428729 | Alanine aminotransferase levels | 1,010,710 European ancestry individuals | T | NR | 5E-133 | 132.302 | rs58542926 | 0.0179 | serum alanine aminotransferase measurement (EFO:0004735) |
PMID:38632349 |
GWAS1039889_H | GCST90239672 | Non-HDL cholesterol levels | 40,963 South Asian ancestry individuals | T | 0.0882445 | 4E-32 | 31.398 | rs58542926 | 0.162845 | non-high density lipoprotein cholesterol measurement (EFO:0005689) |
PMID:34887591 |
GWAS1040204_H | GCST90239673 | Total cholesterol levels | 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals | ? | NR | 2E-585 | 584.699 | rs58542926 | N/A | total cholesterol measurement (EFO:0004574) |
PMID:34887591 |
GWAS1041126_H | GCST90239659 | Low density lipoprotein cholesterol levels | 48,057 Hispanic individuals | T | 0.0461032 | 1E-23 | 23 | rs58542926 | 0.18526 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:34887591 |
GWAS1041430_H | GCST90239667 | Non-HDL cholesterol levels | 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals | ? | NR | 3E-470 | 469.523 | rs58542926 | N/A | non-high density lipoprotein cholesterol measurement (EFO:0005689) |
PMID:34887591 |
None Available | GCST90134368 | lysoPhosphatidylcholine acyl C20:3 levels | 5,505 European ancestry individuals | ? | NR | 9E-9 | 8.046 | rs58542926 | 0.25 | lysophosphatidylcholine 20:3 measurement (EFO:0010362) |
PMID:35888728 |
None Available | GCST90134369 | Phosphatidylcholine diacyl C34:4 levels | 5,505 European ancestry individuals | ? | NR | 2E-11 | 10.699 | rs58542926 | 0.2945 | phosphatidylcholine 34:4 measurement (EFO:0010378) |
PMID:35888728 |
GWAS1042331_H | GCST90239676 | Total cholesterol levels | 1,320,016 European ancestry individuals | T | 0.0749609 | 2E-394 | 393.699 | rs58542926 | 0.129097 | total cholesterol measurement (EFO:0004574) |
PMID:34887591 |
GWAS1042342_H | GCST90239660 | Low density lipoprotein cholesterol levels | 40,963 South Asian ancestry individuals | T | 0.0896894 | 6E-17 | 16.222 | rs58542926 | 0.110629 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:34887591 |
None Available | GCST90300369 | Metabolite levels (linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2]) | 5,248 European, Hispanic or African American individuals | T | 0.0589 | 3E-12 | 11.523 | rs58542926 | 0.291 | linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] measurement (EFO:0800500) |
PMID:37253714 |
GWAS1042485_H | GCST90018944 | Aspartate aminotransferase levels | 342,990 European ancestry individuals, 150,068 East Asian ancestry individuals | T | NR | 1E-42 | 42 | rs58542926 | 0.0493 | aspartate aminotransferase measurement (EFO:0004736) |
PMID:34594039 |
GWAS1042833_H | GCST90018755 | Triglycerides | 111,667 East Asian ancestry individuals | T | 0.07873 | 4E-15 | 14.398 | rs58542926 | 0.058552 | triglyceride measurement (EFO:0004530) |
PMID:34594039 |
GWAS1043836_H | GCST90132184 | Type 2 diabetes | 251,740 European ancestry individuals | T | 0.075 | 5E-13 | 12.302 | rs58542926 | 0.087 | PMID:35551307 | |
GWAS1044960_H | GCST90140949 | Triacylglyceride levels | 22,000 Pakistani and Bangladeshi ancestry individuals | T | 0.09 | 5E-9 | 8.302 | rs58542926 | 0.12 | triglyceride measurement (EFO:0004530) |
PMID:35945198 |
None Available | GCST90140948 | Total cholesterol levels | 22,000 Pakistani and Bangladeshi ancestry individuals | T | 0.1 | 4E-10 | 9.398 | rs58542926 | 0.12 | total cholesterol measurement (EFO:0004574) |
PMID:35945198 |
None Available | GCST90104598 | Nonalcoholic fatty liver disease | 3,711 European ancestry cases, 426,252 European ancestry controls | T | NR | 3E-16 | 15.523 | rs58542926 | 0.39 | non-alcoholic fatty liver disease (EFO:0003095) |
PMID:35124268 |
None Available | GCST90018973 | Total bilirubin levels | 342,829 European ancestry individuals, 124,341 East Asian ancestry individuals | T | NR | 1E-19 | 19 | rs58542926 | 0.0336 | bilirubin measurement (EFO:0004570) |
PMID:34594039 |
None Available | GCST90018975 | Triglycerides | 343,992 European ancestry individuals, 111,667 East Asian ancestry individuals | T | NR | 1E-134 | 134 | rs58542926 | 0.0934 | triglyceride measurement (EFO:0004530) |
PMID:34594039 |
GWAS1047633_H | GCST90239670 | Non-HDL cholesterol levels | 1,320,016 European ancestry individuals | T | 0.0751247 | 1E-326 | 326 | rs58542926 | 0.140021 | non-high density lipoprotein cholesterol measurement (EFO:0005689) |
PMID:34887591 |
GWAS1047748_H | GCST90239658 | Low density lipoprotein cholesterol levels | 1,320,016 European ancestry individuals | T | 0.0752592 | 3E-291 | 290.523 | rs58542926 | 0.110726 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:34887591 |
GWAS1047938_H | GCST90239669 | Non-HDL cholesterol levels | 146,492 East Asian ancestry individuals | T | 0.0669562 | 9E-13 | 12.046 | rs58542926 | 0.0784508 | non-high density lipoprotein cholesterol measurement (EFO:0005689) |
PMID:34887591 |
None Available | GCST90132183 | Type 2 diabetes | 251,740 European ancestry individuals, 139,705 East Asian ancestry individuals, 40,737 South Asian ancestry individuals, 27,417 Hispanic individuals, 30,167 African American individuals, 2,426 Zulu ancestry individuals | T | NR | 5E-12 | 11.302 | rs58542926 | 1.07 | PMID:35551307 | |
None Available | GCST90448599 | Alanine aminotransferase levels | 38,000 South Asian ancestry individuals | T | NR | 3E-15 | 14.523 | rs58542926 | 0.083 | serum alanine aminotransferase measurement (EFO:0004735) |
PMID:39414775 |
None Available | GCST90448633 | Triglyceride levels | 38,000 South Asian ancestry individuals | T | NR | 4E-39 | 38.398 | rs58542926 | 0.163 | triglyceride measurement (EFO:0004530) |
PMID:39414775 |
None Available | GCST90448631 | Total cholesterol levels | 38,000 South Asian ancestry individuals | T | NR | 2E-35 | 34.699 | rs58542926 | 0.154 | total cholesterol measurement (EFO:0004574) |
PMID:39414775 |
None Available | GCST90448622 | Non-HDL cholesterol levels | 38,000 South Asian ancestry individuals | T | NR | 1E-24 | 24 | rs58542926 | 0.162 | non-high density lipoprotein cholesterol measurement (EFO:0005689) |
PMID:39414775 |
None Available | GCST90448616 | LDL cholesterol levels | 38,000 South Asian ancestry individuals | T | NR | 5E-17 | 16.302 | rs58542926 | 0.111 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:39414775 |
RGD Curation Notes
Note Type | Note | Reference |
---|