GWAS982919_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS982919_H (very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS982919 (human)) Homo sapiens

Symbol: GWAS982919_H
Name: very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS982919 (human)
RGD ID: 407333943
Trait: very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio
Measurement Type: blood very low density lipoprotein cholesterol level   (CMO:0000648)    
LOD Score: Not Available
P Value: 9.0E-25
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh386161,238,337 - 161,238,338RGD_MAPPER_PIPELINEGRCh38
GRCh376161,659,369 - 161,659,370RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS982919_HHumanblood very low density lipoprotein cholesterol level  IAGPrs148349043405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS982919_HHumancholesteryl esters:total lipids ratio  IAGPrs148349043405850206 GWAS_CATALOGPMID:35213538
GWAS982919_HHumanvery low density lipoprotein cholesterol measurement  IAGPrs148349043405850206 GWAS_CATALOGPMID:35213538
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1354001AGPAT41-acylglycerol-3-phosphate O-acyltransferase 46161129967161274061Human

Position Markers

Peak: (rs148349043)
Human AssemblyChrPosition (strand)Source
GRCh386161,238,337 - 161,238,338RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407314055GWAS963031_Hlow density lipoprotein cholesterol measurement QTL GWAS963031 (human)3e-41low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)6161238337161238338Human
407258372GWAS907348_Hlow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS907348 (human)2e-14low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)6161238337161238338Human
407308801GWAS957777_Hchylomicron measurement, very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS957777 (human)2e-18chylomicron measurement, very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)6161238337161238338Human
407308224GWAS957200_Hchylomicron measurement, very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS957200 (human)1e-28chylomicron measurement, very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)6161238337161238338Human
407328715GWAS977691_Htriglyceride measurement QTL GWAS977691 (human)3e-20non-high density lipoprotein cholesterol measurementblood non-high density lipoprotein cholesterol level (CMO:0003967)6161238337161238338Human
407308488GWAS957464_Hchylomicron measurement, triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement QTL GWAS957464 (human)3e-26chylomicron measurement, triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6161238337161238338Human
407316693GWAS965669_Htotal cholesterol measurement QTL GWAS965669 (human)7e-30total cholesterol measurementblood total cholesterol level (CMO:0000051)6161238337161238338Human
1643404BMD3_HBone mineral density QTL 3 (human)2.420.0005Bone mineral density6157563614170805979Human
407183327GWAS832303_Hvery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio QTL GWAS832303 (human)6e-16very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)6161238337161238338Human
407315546GWAS964522_Hnon-high density lipoprotein cholesterol measurement QTL GWAS964522 (human)4e-24non-high density lipoprotein cholesterol measurementblood non-high density lipoprotein cholesterol level (CMO:0003967)6161238337161238338Human
407315682GWAS964658_Hlow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS964658 (human)7e-16low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)6161238337161238338Human
407286369GWAS935345_Hfatty acid measurement QTL GWAS935345 (human)5e-08fatty acid measurement6161238337161238338Human
407327968GWAS976944_Hvery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS976944 (human)2e-10very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)6161238337161238338Human
407296558GWAS945534_Hvery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS945534 (human)1e-09very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)6161238337161238338Human
407326319GWAS975295_Htriglyceride measurement, low density lipoprotein cholesterol measurement QTL GWAS975295 (human)1e-20triglyceride measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)6161238337161238338Human
407316654GWAS965630_Hlow density lipoprotein cholesterol measurement QTL GWAS965630 (human)1e-32low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)6161238337161238338Human
407333943GWAS982919_Hvery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS982919 (human)9e-25very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)6161238337161238338Human
407344437GWAS993413_Htriglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS993413 (human)3e-10triglyceride measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)6161238337161238338Human
407287475GWAS936451_Hvery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio QTL GWAS936451 (human)8e-09very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)6161238337161238338Human
407331837GWAS980813_Hvery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio QTL GWAS980813 (human)7e-23very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)6161238337161238338Human
407308986GWAS957962_Hchylomicron measurement, very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio QTL GWAS957962 (human)3e-25chylomicron measurement, very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)6161238337161238338Human
407324282GWAS973258_Htotal cholesterol measurement QTL GWAS973258 (human)6e-23total cholesterol measurementblood total cholesterol level (CMO:0000051)6161238337161238338Human
407333434GWAS982410_Htriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement QTL GWAS982410 (human)2e-17triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6161238337161238338Human
1643367BW323_HBody weight QTL 323 (human)2.420.0005Body fat amount6157563614170805979Human
407325560GWAS974536_Htriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS974536 (human)8e-12triglycerides:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)6161238337161238338Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS832303_H GCST90092869 Cholesterol to total lipids ratio in large VLDL 115,071 European ancestry individuals C 0.986455 6E-16 15.222 rs148349043 0.15092 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesterol:total lipids ratio (EFO:0020943)
 PMID:35213538
GWAS907348_H GCST90092909 Free cholesterol to total lipids ratio in medium LDL 115,082 European ancestry individuals C 0.986456 2E-14 13.699 rs148349043 0.139585 low density lipoprotein cholesterol measurement (EFO:0004611)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
GWAS935345_H GCST90092935 Ratio of omega-6 fatty acids to total fatty acids 115,006 European ancestry individuals C 0.986455 5E-8 7.302 rs148349043 0.100068 fatty acid measurement (EFO:0005110)
 PMID:35213538
GWAS936451_H GCST90092917 Cholesterol to total lipids ratio in medium VLDL 115,082 European ancestry individuals C 0.986456 8E-9 8.097 rs148349043 0.10351 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesterol:total lipids ratio (EFO:0020943)
 PMID:35213538
GWAS945534_H GCST90092919 Cholesteryl esters to total lipids ratio in medium VLDL 115,082 European ancestry individuals C 0.986456 1E-9 9 rs148349043 0.108672 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:35213538
GWAS957200_H GCST90093045 Free cholesterol to total lipids ratio in chylomicrons and extremely large VLDL 111,638 European ancestry individuals C 0.986698 1E-28 28 rs148349043 0.213258 chylomicron measurement (EFO:0008596)
very low density lipoprotein cholesterol measurement (EFO:0008317)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
GWAS957464_H GCST90093051 Triglycerides to total lipids ratio in chylomicrons and extremely large VLDL 111,638 European ancestry individuals C 0.986698 3E-26 25.523 rs148349043 0.205718 chylomicron measurement (EFO:0008596)
triglycerides:total lipids ratio (EFO:0020947)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS957777_H GCST90093043 Cholesteryl esters to total lipids ratio in chylomicrons and extremely large VLDL 111,638 European ancestry individuals C 0.986698 2E-18 17.699 rs148349043 0.170072 chylomicron measurement (EFO:0008596)
very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:35213538
GWAS957962_H GCST90093041 Cholesterol to total lipids ratio in chylomicrons and extremely large VLDL 111,638 European ancestry individuals C 0.986698 3E-25 24.523 rs148349043 0.20013 chylomicron measurement (EFO:0008596)
very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesterol:total lipids ratio (EFO:0020943)
 PMID:35213538
GWAS963031_H GCST90239655 Low density lipoprotein cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 3E-41 40.523 rs148349043 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:34887591
GWAS964522_H GCST90239667 Non-HDL cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 4E-24 23.398 rs148349043 N/A non-high density lipoprotein cholesterol measurement (EFO:0005689)
 PMID:34887591
GWAS964658_H GCST90092961 Free cholesterol to total lipids ratio in small LDL 115,082 European ancestry individuals C 0.986456 7E-16 15.155 rs148349043 0.148535 low density lipoprotein cholesterol measurement (EFO:0004611)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
GWAS965630_H GCST90239658 Low density lipoprotein cholesterol levels 1,320,016 European ancestry individuals G 0.0139227 1E-32 32 rs148349043 0.0847064 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:34887591
GWAS965669_H GCST90239673 Total cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 7E-30 29.155 rs148349043 N/A total cholesterol measurement (EFO:0004574)
 PMID:34887591
GWAS973258_H GCST90239676 Total cholesterol levels 1,320,016 European ancestry individuals G 0.0139319 6E-23 22.222 rs148349043 0.0701836 total cholesterol measurement (EFO:0004574)
 PMID:34887591
GWAS974536_H GCST90092967 Triglycerides to total lipids ratio in small LDL 115,082 European ancestry individuals C 0.986456 8E-12 11.097 rs148349043 0.12558 triglycerides:total lipids ratio (EFO:0020947)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS975295_H GCST90092966 Triglyceride levels in small LDL 115,082 European ancestry individuals C 0.986456 1E-20 20 rs148349043 0.172114 triglyceride measurement (EFO:0004530)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS976944_H GCST90093021 Free cholesterol to total lipids ratio in very large VLDL 114,160 European ancestry individuals C 0.9865120000000001 2E-10 9.699 rs148349043 0.117704 very low density lipoprotein cholesterol measurement (EFO:0008317)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
GWAS977691_H GCST90092992 Total triglycerides levels 115,082 European ancestry individuals C 0.986456 3E-20 19.523 rs148349043 0.169475 triglyceride measurement (EFO:0004530)
 PMID:35213538
None Available GCST90239670 Non-HDL cholesterol levels 1,320,016 European ancestry individuals G 0.0135557 3E-20 19.523 rs148349043 0.079586 non-high density lipoprotein cholesterol measurement (EFO:0005689)
 PMID:34887591
GWAS980813_H GCST90093017 Cholesterol to total lipids ratio in very large VLDL 114,160 European ancestry individuals C 0.9865120000000001 7E-23 22.155 rs148349043 0.179974 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesterol:total lipids ratio (EFO:0020943)
 PMID:35213538
GWAS982410_H GCST90093027 Triglycerides to total lipids ratio in very large VLDL 114,160 European ancestry individuals C 0.9865120000000001 2E-17 16.699 rs148349043 0.156819 triglycerides:total lipids ratio (EFO:0020947)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS982919_H GCST90093019 Cholesteryl esters to total lipids ratio in very large VLDL 114,160 European ancestry individuals C 0.9865120000000001 9E-25 24.046 rs148349043 0.187873 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:35213538
GWAS993413_H GCST90093014 Triglyceride levels in very large HDL 115,082 European ancestry individuals C 0.986456 3E-10 9.523 rs148349043 0.117643 triglyceride measurement (EFO:0004530)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90446535 Cardiovascular disease 44,238 European ancestry cases, 414,900 European ancestry controls ? NR 5E-9 8.302 rs148349043 N/A cardiovascular disease (EFO:0000319)
 PMID:37947095
None Available GCST90446534 Coronary heart disease 38,687 European ancestry cases, 420,451 European ancestry controls ? NR 1E-9 9 rs148349043 N/A coronary artery disease (EFO:0001645)
 PMID:37947095
None Available GCST90446533 Angina 25,257 European ancestry cases, 433,881 European ancestry controls ? NR 2E-9 8.699 rs148349043 N/A angina pectoris (EFO:0003913)
 PMID:37947095
Database Acc Id Source(s)
GWAS Catalog GCST90093019 GWAS Catalog

RGD Curation Notes
Note Type Note Reference