GWAS970607_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS970607_H (linoleic acid measurement QTL GWAS970607 (human)) Homo sapiens

Symbol: GWAS970607_H
Name: linoleic acid measurement QTL GWAS970607 (human)
RGD ID: 407321631
Trait: linoleic acid measurement
Measurement Type: blood free fatty acids level   (CMO:0000117)    
LOD Score: Not Available
P Value: 3.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh386159,979,115 - 159,979,116RGD_MAPPER_PIPELINEGRCh38
GRCh376160,400,147 - 160,400,148RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS970607_HHumanblood free fatty acids level  IAGPrs7750288405850206Based on the EFO term IDGWAS_CATALOGPMID:35692035

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS970607_HHumanlinoleic acid measurement  IAGPrs7750288405850206 GWAS_CATALOGPMID:35692035
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
732660IGF2Rinsulin like growth factor 2 receptor6159969082160111504Human

Position Markers

Peak: (rs7750288)
Human AssemblyChrPosition (strand)Source
GRCh386159,979,115 - 159,979,116RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407274980GWAS923956_Hserum metabolite measurement QTL GWAS923956 (human)1e-17serum metabolite measurement6159979115159979116Human
1643404BMD3_HBone mineral density QTL 3 (human)2.420.0005Bone mineral density6157563614170805979Human
406924868GWAS573844_Hsleep duration, low density lipoprotein cholesterol measurement QTL GWAS573844 (human)2e-11familial hyperlipidemiablood low density lipoprotein cholesterol level (CMO:0000053)6159979115159979116Human
407321631GWAS970607_Hlinoleic acid measurement QTL GWAS970607 (human)3e-09linoleic acid measurementblood free fatty acids level (CMO:0000117)6159979115159979116Human
407094442GWAS743418_HX-14939 measurement QTL GWAS743418 (human)3e-10X-14939 measurement6159979115159979116Human
407239096GWAS888072_Hfamilial hyperlipidemia QTL GWAS888072 (human)5e-10familial hyperlipidemia6159979115159979116Human
1643367BW323_HBody weight QTL 323 (human)2.420.0005Body fat amount6157563614170805979Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS573844_H GCST009366 LDL cholesterol levels x long total sleep time interaction (2df test) 2,913 African American long sleepers, 358 Chinese ancestry long sleepers, 110 Asian ancestry long sleepers, 7,583 European ancestry long sleepers, 1,036 Hispanic/Latino long sleepers, up to 11,862 African American controls, 1,432 Chinese ancestry controls, 444 Asian ancestry controls, at least 31,744 European ancestry controls, 4,066 Hispanic/Latino controls ? NR 2E-11 10.699 rs7750288 1.535 sleep duration (EFO:0005271)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:31719535
GWAS743418_H GCST90245596 X-14939 levels 14,296 European ancestry individuals A 0.714 3E-10 9.523 rs7750288 0.069316216 X-14939 measurement (EFO:0800747)
 PMID:36357675
GWAS888072_H GCST90104005 Familial combined hyperlipidemia defined by Dutch criteria 17,485 British ancestry cases, 331,737 British ancestry controls A 0.713739 5E-10 9.302 rs7750288 0.0760462 PMID:34906840
None Available GCST90104006 Familial combined hyperlipidemia defined by Consensus criteria 39,961 British ancestry cases, 309,261 British ancestry controls A 0.713739 2E-11 10.699 rs7750288 0.0566373 PMID:34906840
GWAS923956_H GCST012021 Serum metabolite levels 3,926 Hispanic/Latino individuals A 0.722236 1E-17 17 rs7750288 0.215 serum metabolite measurement (EFO:0005653)
 PMID:33031748
None Available GCST012020 Serum metabolite levels 3,926 Hispanic/Latino individuals A 0.722236 1E-17 17 rs7750288 0.215 serum metabolite measurement (EFO:0005653)
 PMID:33031748
GWAS970607_H GCST90133363 Linoleic acid levels 114,999 European ancestry individuals A 0.71 3E-9 8.523 rs7750288 0.027 linoleic acid measurement (EFO:0006807)
 PMID:35692035
Database Acc Id Source(s)
GWAS Catalog GCST90133363 GWAS Catalog

RGD Curation Notes
Note Type Note Reference