GWAS969971_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS969971_H (glomerular filtration rate QTL GWAS969971 (human)) Homo sapiens

Symbol: GWAS969971_H
Name: glomerular filtration rate QTL GWAS969971 (human)
RGD ID: 407320995
Trait: glomerular filtration rate
Measurement Type: glomerular filtration rate   (CMO:0000490)    
LOD Score: Not Available
P Value: 7.0E-17
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38476,368,255 - 76,368,256RGD_MAPPER_PIPELINEGRCh38
GRCh37477,289,408 - 77,289,409RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS969971_HHumanglomerular filtration rate  IAGPrs72657823405850206Based on the EFO term IDGWAS_CATALOGPMID:33462484

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS969971_HHumanglomerular filtration rate  IAGPrs72657823405850206 GWAS_CATALOGPMID:33462484
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1602411CCDC158coiled-coil domain containing 15847631303976421869Human

Position Markers

Peak: (rs72657823)
Human AssemblyChrPosition (strand)Source
GRCh38476,368,255 - 76,368,256RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407254165GWAS903141_Hcystatin C measurement QTL GWAS903141 (human)5e-14cystatin C measurementblood cystatin C level (CMO:0002777)47636825576368256Human
407254101GWAS903077_Hcreatinine measurement QTL GWAS903077 (human)4e-17creatinine measurementblood creatinine measurement (CMO:0000767)47636825576368256Human
407320995GWAS969971_Hglomerular filtration rate QTL GWAS969971 (human)7e-17glomerular filtration rateglomerular filtration rate (CMO:0000490)47636825576368256Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS903077_H GCST90019502 Creatinine levels 342,376 European ancestry individuals, 6,016 African ancestry individuals, 7,339 South Asian ancestry individuals A NR 4E-17 16.398 rs72657823 0.0425 creatinine measurement (EFO:0004518)
 PMID:33462484
GWAS903141_H GCST90019504 Cystatin C levels 342,399 European ancestry individuals, 6,015 African ancestry individuals, 7,338 South Asian ancestry individuals A NR 5E-14 13.302 rs72657823 0.038 cystatin C measurement (EFO:0004617)
 PMID:33462484
GWAS969971_H GCST90019506 Estimated glomerular filtration rate 342,376 European ancestry individuals, 6,016 African ancestry individuals, 7,339 South Asian ancestry individuals A NR 7E-17 16.155 rs72657823 0.0421 glomerular filtration rate (EFO:0005208)
 PMID:33462484
Database Acc Id Source(s)
GWAS Catalog GCST90019506 GWAS Catalog

RGD Curation Notes
Note Type Note Reference