GWAS954962_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS954962_H (lean body mass QTL GWAS954962 (human)) Homo sapiens

Symbol: GWAS954962_H
Name: lean body mass QTL GWAS954962 (human)
RGD ID: 407305986
Trait: body lean mass   (VT:0010483)    
Measurement Type: total body lean mass   (CMO:0003950)    
LOD Score: Not Available
P Value: 3.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh383154,301,098 - 154,301,099RGD_MAPPER_PIPELINEGRCh38
GRCh373154,018,887 - 154,018,888RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS954962_HHumantotal body lean mass  IAGPrs9438405850206Based on the EFO term IDGWAS_CATALOGPMID:38538606

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS954962_HHumanbody lean mass  IAGPrs9438405850206Based on the EFO term IDGWAS_CATALOGPMID:38538606

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS954962_HHumanlean body mass  IAGPrs9438405850206 GWAS_CATALOGPMID:38538606
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Vertebrate Trait
body lean mass  (IAGP)

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1318732DHX36DEAH-box helicase 363154272546154324487Human

Position Markers

Peak: (rs9438)
Human AssemblyChrPosition (strand)Source
GRCh383154,301,098 - 154,301,099RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406996816GWAS645792_Hbody mass index QTL GWAS645792 (human)6e-21body mass indexbody mass index (BMI) (CMO:0000105)3154301098154301099Human
407305986GWAS954962_Hlean body mass QTL GWAS954962 (human)3e-10body lean mass (VT:0010483)total body lean mass (CMO:0003950)3154301098154301099Human
407371599GWAS1020575_Hbody mass index QTL GWAS1020575 (human)0.000001body mass indexbody mass index (BMI) (CMO:0000105)3154301098154301099Human
1300026BP36_HBlood pressure QTL 36 (human)4.04Blood pressurehypertension susceptibility3135720453161720453Human
1298415BP24_HBlood pressure QTL 24 (human)2.9Blood pressurehypertension susceptibility3135720453161720453Human
407371464GWAS1020440_Hbody mass index QTL GWAS1020440 (human)2e-13body mass indexbody mass index (BMI) (CMO:0000105)3154301098154301099Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS645792_H GCST90255621 Body mass index 1,122,049 European ancestry individuals G NR 6E-21 20.222 rs9438 0.0125 body mass index (EFO:0004340)
 PMID:36581621
GWAS954962_H GCST90428120 Whole body fat free mass (UKB data field 23101) 337,739 European ancestry individuals C NR 3E-10 9.523 rs9438 0.00852751 lean body mass (EFO:0004995)
 PMID:38538606
GWAS1020440_H GCST008129 Body mass index up to 449,889 European ancestry individuals, up to 29,398 South Asian ancestry individuals, up to 27,610 African American individuals, up to 8,839 East Asian individuals, up to 10,772 Hispanic ancestry individuals C 0.3991 2E-13 12.699 rs9438 0.013 body mass index (EFO:0004340)
 PMID:29273807
GWAS1020575_H GCST006368 Body mass index 315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals G NR 0.000001 6 rs9438 0.014 body mass index (EFO:0004340)
 PMID:30108127
Database Acc Id Source(s)
GWAS Catalog GCST90428120 GWAS Catalog

RGD Curation Notes
Note Type Note Reference