GWAS951275_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS951275_H (hearing loss QTL GWAS951275 (human)) Homo sapiens

Symbol: GWAS951275_H
Name: hearing loss QTL GWAS951275 (human)
RGD ID: 407302299
Trait: hearing loss
LOD Score: Not Available
P Value: 3.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh386158,084,822 - 158,084,823RGD_MAPPER_PIPELINEGRCh38
GRCh376158,505,854 - 158,505,855RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
Hearing Loss  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
69494SYNJ2synaptojanin 26157981296158099176Human

Position Markers

Peak: (rs6902016)
Human AssemblyChrPosition (strand)Source
GRCh386158,084,822 - 158,084,823RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407064530GWAS713506_Hage-related hearing impairment QTL GWAS713506 (human)1e-12age-related hearing impairment6158084822158084823Human
1643404BMD3_HBone mineral density QTL 3 (human)2.420.0005Bone mineral density6157563614170805979Human
407302299GWAS951275_Hhearing loss QTL GWAS951275 (human)3e-11hearing loss6158084822158084823Human
1643367BW323_HBody weight QTL 323 (human)2.420.0005Body fat amount6157563614170805979Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS713506_H GCST90012115 Age-related hearing impairment (MTAG) 330,759 European ancestry individuals ? NR 1E-12 12 rs6902016 7.124813 age-related hearing impairment (EFO:0005782)
 PMID:32986727
GWAS951275_H GCST90044775 Hearing difficulty 91,080 European ancestry cases, 257,037 European ancestry controls ? NR 3E-11 10.523 rs6902016 N/A hearing loss (EFO:0004238)
 PMID:34847940
Database Acc Id Source(s)
GWAS Catalog GCST90044775 GWAS Catalog

RGD Curation Notes
Note Type Note Reference