GWAS932935_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS932935_H (Alzheimer disease, peptic ulcer disease QTL GWAS932935 (human)) Homo sapiens

Symbol: GWAS932935_H
Name: Alzheimer disease, peptic ulcer disease QTL GWAS932935 (human)
RGD ID: 407283959
Trait: Alzheimer disease, peptic ulcer disease
LOD Score: Not Available
P Value: 2.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381951,227,920 - 51,227,921RGD_MAPPER_PIPELINEGRCh38
GRCh371951,731,176 - 51,731,177RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS932935_HHumanAlzheimer disease  IAGPrs7245846405850206 GWAS_CATALOGPMID:35851147
GWAS932935_HHumanpeptic ulcer disease  IAGPrs7245846405850206 GWAS_CATALOGPMID:35851147
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
38667249LOC107985327uncharacterized LOC107985327195118690851271167Human
1347694CD33CD33 molecule195121107651240016Human

Position Markers

Peak: (rs7245846)
Human AssemblyChrPosition (strand)Source
GRCh381951,227,920 - 51,227,921RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1559110SCL22_HSerum cholesterol level QTL 22 (human)3.590.000241Lipid levelLDL cholesterol193190759457907594Human
407283959GWAS932935_HAlzheimer disease, peptic ulcer disease QTL GWAS932935 (human)2e-08Alzheimer disease, peptic ulcer disease195122792051227921Human
407207652GWAS856628_Hblood protein measurement QTL GWAS856628 (human)2e-150blood protein measurementblood protein measurement (CMO:0000028)195122792051227921Human
407207943GWAS856919_Hblood protein measurement QTL GWAS856919 (human)6e-143blood protein measurementblood protein measurement (CMO:0000028)195122792051227921Human
407208886GWAS857862_Hblood protein measurement QTL GWAS857862 (human)1e-58blood protein measurementblood protein measurement (CMO:0000028)195122792051227921Human
1331657COPD9_HChronic obstructive pulmonary disease QTL 9 (human)1.94Chronic airflow obstructionpost-bronchodilator FEV1193102176057021760Human
407267209GWAS916185_Hmyeloid white cell count QTL GWAS916185 (human)3e-15myeloid white cell countwhite blood cell count (CMO:0000027)195122792051227921Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS856628_H GCST90001954 CD33 on basophil 1,555 Sardinian (founder/genetic isolate) ancestry individuals A 0.19394 2E-150 149.699 rs7245846 1.131 blood protein measurement (EFO:0007937)
 PMID:32929287
GWAS856919_H GCST90001955 CD33 on Immature Myeloid-Derived Suppressor Cells 1,554 Sardinian (founder/genetic isolate) ancestry individuals A 0.19342 6E-143 142.222 rs7245846 1.115 blood protein measurement (EFO:0007937)
 PMID:32929287
GWAS857862_H GCST90001950 CD33 on Granulocytic Myeloid-Derived Suppressor Cells 1,244 Sardinian (founder/genetic isolate) ancestry individuals A 0.18535 1E-58 58 rs7245846 0.8358 blood protein measurement (EFO:0007937)
 PMID:32929287
GWAS916185_H GCST90001519 CD33+ HLA DR+ CD14- %CD33+ HLA DR+ 1,858 Sardinian (founder/genetic isolate) ancestry individuals A 0.22367 3E-15 14.523 rs7245846 0.3128 myeloid white cell count (EFO:0007988)
 PMID:32929287
GWAS932935_H GCST90134604 Alzheimer's disease or peptic ulcer disease 71,880 European ancestry Alzheimer's disease or AD-by-proxy cases, 16,666 European ancestry peptic ulcer disease cases, up to 823,039 European ancestry controls A NR 2E-8 7.699 rs7245846 N/A PMID:35851147
Database Acc Id Source(s)
GWAS Catalog GCST90134604 GWAS Catalog

RGD Curation Notes
Note Type Note Reference