GWAS930532_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS930532_H (triglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS930532 (human)) Homo sapiens

Symbol: GWAS930532_H
Name: triglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS930532 (human)
RGD ID: 407281556
Trait: triglyceride measurement, high density lipoprotein cholesterol measurement
Measurement Type: blood high density lipoprotein cholesterol level   (CMO:0000052)    
blood triglyceride level   (CMO:0000118)    
LOD Score: Not Available
P Value: 4.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh386160,080,793 - 160,080,794RGD_MAPPER_PIPELINEGRCh38
GRCh376160,501,825 - 160,501,826RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS930532_HHumanblood high density lipoprotein cholesterol level  IAGPrs78425119405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538
GWAS930532_HHumanblood triglyceride level  IAGPrs78425119405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS930532_HHumanhigh density lipoprotein cholesterol measurement  IAGPrs78425119405850206 GWAS_CATALOGPMID:35213538
GWAS930532_HHumantriglyceride measurement  IAGPrs78425119405850206 GWAS_CATALOGPMID:35213538
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
732660IGF2Rinsulin like growth factor 2 receptor6159969082160111504Human

Position Markers

Peak: (rs78425119)
Human AssemblyChrPosition (strand)Source
GRCh386160,080,793 - 160,080,794RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407182757GWAS831733_Hvery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS831733 (human)3e-08very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)6160080793160080794Human
407333061GWAS982037_HIGF-1 measurement QTL GWAS982037 (human)5e-17IGF-1 measurementblood insulin-like growth factor 1 level (CMO:0001297)6160080793160080794Human
407344837GWAS993813_Htriglyceride measurement QTL GWAS993813 (human)6e-15triglyceride measurementblood triglyceride level (CMO:0000118)6160080793160080794Human
407186990GWAS835966_Htriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement QTL GWAS835966 (human)3e-09triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160080793160080794Human
407076687GWAS725663_Hfatty acid measurement QTL GWAS725663 (human)2e-11fatty acid measurement6160080793160080794Human
407296235GWAS945211_Hhigh density lipoprotein cholesterol measurement QTL GWAS945211 (human)1e-16high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)6160080793160080794Human
407333463GWAS982439_Htriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS982439 (human)2e-10triglycerides:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)6160080793160080794Human
407276951GWAS925927_Htotal cholesterol measurement QTL GWAS925927 (human)4e-33total cholesterol measurementblood total cholesterol level (CMO:0000051)6160080793160080794Human
407281556GWAS930532_Htriglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS930532 (human)4e-08triglyceride measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)6160080793160080794Human
407316691GWAS965667_Htotal cholesterol measurement QTL GWAS965667 (human)1e-65total cholesterol measurementblood total cholesterol level (CMO:0000051)6160080793160080794Human
1643404BMD3_HBone mineral density QTL 3 (human)2.420.0005Bone mineral density6157563614170805979Human
407310719GWAS959695_Htriglyceride measurement QTL GWAS959695 (human)4e-24triglyceride measurementblood triglyceride level (CMO:0000118)6160080793160080794Human
407286079GWAS935055_Hhigh density lipoprotein cholesterol measurement QTL GWAS935055 (human)9e-13high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)6160080793160080794Human
407309531GWAS958507_Hlow density lipoprotein cholesterol measurement QTL GWAS958507 (human)9e-38low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)6160080793160080794Human
407331642GWAS980618_Htriglyceride measurement QTL GWAS980618 (human)2e-29triglyceride measurementblood triglyceride level (CMO:0000118)6160080793160080794Human
1643367BW323_HBody weight QTL 323 (human)2.420.0005Body fat amount6157563614170805979Human
407268632GWAS917608_Hapolipoprotein B measurement QTL GWAS917608 (human)1e-40apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)6160080793160080794Human
407315544GWAS964520_Hnon-high density lipoprotein cholesterol measurement QTL GWAS964520 (human)6e-69non-high density lipoprotein cholesterol measurementblood non-high density lipoprotein cholesterol level (CMO:0003967)6160080793160080794Human
407329336GWAS978312_Hnon-high density lipoprotein cholesterol measurement QTL GWAS978312 (human)6e-55non-high density lipoprotein cholesterol measurementblood non-high density lipoprotein cholesterol level (CMO:0003967)6160080793160080794Human
407324280GWAS973256_Htotal cholesterol measurement QTL GWAS973256 (human)5e-51total cholesterol measurementblood total cholesterol level (CMO:0000051)6160080793160080794Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS725663_H GCST90301960 Ratio of omega-3 fatty acids to total fatty acids 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.0668 2E-11 10.699 rs78425119 0.0568 fatty acid measurement (EFO:0005110)
 PMID:38448586
GWAS831733_H GCST90092873 Free cholesterol to total lipids ratio in large VLDL 115,071 European ancestry individuals G 0.931942 3E-8 7.523 rs78425119 0.0446862 very low density lipoprotein cholesterol measurement (EFO:0008317)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
GWAS835966_H GCST90092879 Triglycerides to total lipids ratio in large VLDL 115,071 European ancestry individuals G 0.931942 3E-9 8.523 rs78425119 0.0482762 triglycerides:total lipids ratio (EFO:0020947)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS917608_H GCST90019496 Apolipoprotein B levels 340,860 European ancestry individuals, 5,962 African ancestry individuals, 7,275 South Asian ancestry individuals A NR 1E-40 40 rs78425119 0.0637 apolipoprotein B measurement (EFO:0004615)
 PMID:33462484
GWAS925927_H GCST90019501 Total cholesterol levels 342,508 European ancestry individuals, 6,014 African ancestry individuals, 7,336 South Asian ancestry individuals A NR 4E-33 32.398 rs78425119 0.057 total cholesterol measurement (EFO:0004574)
 PMID:33462484
GWAS930532_H GCST90092902 Triglyceride levels in medium HDL 115,082 European ancestry individuals G 0.931944 4E-8 7.398 rs78425119 0.044194 triglyceride measurement (EFO:0004530)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS935055_H GCST90239652 High density lipoprotein cholesterol levels 1,320,016 European ancestry individuals A 0.0660295 9E-13 12.046 rs78425119 0.0257746 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:34887591
GWAS945211_H GCST90239649 High density lipoprotein cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 1E-16 16 rs78425119 N/A high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:34887591
GWAS958507_H GCST90019512 Low density lipoprotein cholesterol levels 341,875 European ancestry individuals, 6,003 African ancestry individuals, 7,319 South Asian ancestry individuals A NR 9E-38 37.046 rs78425119 0.0612 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:33462484
GWAS959695_H GCST90239664 Triglyceride levels 1,320,016 European ancestry individuals A 0.0662585 4E-24 23.398 rs78425119 0.0345754 triglyceride measurement (EFO:0004530)
 PMID:34887591
GWAS964520_H GCST90239667 Non-HDL cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 6E-69 68.222 rs78425119 N/A non-high density lipoprotein cholesterol measurement (EFO:0005689)
 PMID:34887591
GWAS965667_H GCST90239673 Total cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 1E-65 65 rs78425119 N/A total cholesterol measurement (EFO:0004574)
 PMID:34887591
GWAS973256_H GCST90239676 Total cholesterol levels 1,320,016 European ancestry individuals A 0.065956 5E-51 50.302 rs78425119 0.0482598 total cholesterol measurement (EFO:0004574)
 PMID:34887591
GWAS978312_H GCST90239670 Non-HDL cholesterol levels 1,320,016 European ancestry individuals A 0.0653876 6E-55 54.222 rs78425119 0.0594699 non-high density lipoprotein cholesterol measurement (EFO:0005689)
 PMID:34887591
GWAS980618_H GCST90239661 Triglyceride levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 2E-29 28.699 rs78425119 N/A triglyceride measurement (EFO:0004530)
 PMID:34887591
GWAS982037_H GCST90019511 Insulin-like growth factor 1 levels 340,567 European ancestry individuals, 5,974 African ancestry individuals, 7,283 South Asian ancestry individuals A NR 5E-17 16.302 rs78425119 0.04 IGF-1 measurement (EFO:0004627)
 PMID:33462484
GWAS982439_H GCST90093015 Triglycerides to total lipids ratio in very large HDL 115,056 European ancestry individuals G 0.931946 2E-10 9.699 rs78425119 0.0489564 triglycerides:total lipids ratio (EFO:0020947)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS993813_H GCST90019523 Triglyceride levels 342,233 European ancestry individuals, 6,014 African ancestry individuals, 7,330 South Asian ancestry individuals A NR 6E-15 14.222 rs78425119 0.0372 triglyceride measurement (EFO:0004530)
 PMID:33462484
Database Acc Id Source(s)
GWAS Catalog GCST90092902 GWAS Catalog

RGD Curation Notes
Note Type Note Reference