GWAS917970_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS917970_H (cholesterol:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS917970 (human)) Homo sapiens

Symbol: GWAS917970_H
Name: cholesterol:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS917970 (human)
RGD ID: 407268994
Trait: cholesterol:total lipids ratio, intermediate density lipoprotein measurement
Measurement Type: blood intermediate density lipoprotein cholesterol level   (CMO:0001562)    
LOD Score: Not Available
P Value: 9.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38820,084,145 - 20,084,146RGD_MAPPER_PIPELINEGRCh38
GRCh37819,941,656 - 19,941,657RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS917970_HHumanblood intermediate density lipoprotein cholesterol level  IAGPrs75662196405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS917970_HHumancholesterol:total lipids ratio  IAGPrs75662196405850206 GWAS_CATALOGPMID:35213538
GWAS917970_HHumanintermediate density lipoprotein measurement  IAGPrs75662196405850206 GWAS_CATALOGPMID:35213538
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
38661331LOC105379311uncharacterized LOC10537931182007919920124857Human

Position Markers

Peak: (rs75662196)
Human AssemblyChrPosition (strand)Source
GRCh38820,084,145 - 20,084,146RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298482BP2_HBlood pressure QTL 2 (human)1.8Blood pressurediastolic8695325632953256Human
407268994GWAS917970_Hcholesterol:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS917970 (human)9e-10cholesterol:total lipids ratio, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)82008414520084146Human
407308258GWAS957234_Hhigh density lipoprotein cholesterol measurement QTL GWAS957234 (human)1e-10high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)82008414520084146Human
407316865GWAS965841_Htriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS965841 (human)2e-10very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)82008414520084146Human
407193804GWAS842780_Hlow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS842780 (human)1e-09free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)82008414520084146Human
407049353GWAS698329_Hsexual dimorphism measurement QTL GWAS698329 (human)3e-08triglycerides:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)82008414520084146Human
407239374GWAS888350_Htriglycerides:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS888350 (human)4e-10triglycerides:total lipids ratio, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)82008414520084146Human
407151656GWAS800632_Hhigh density lipoprotein cholesterol measurement QTL GWAS800632 (human)9e-31high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)82008414520084146Human
407187464GWAS836440_Hcholesterol:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS836440 (human)8e-09cholesterol:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)82008414520084146Human
407330005GWAS978981_Htriglyceride measurement, phospholipid measurement QTL GWAS978981 (human)7e-09triglyceride measurement, phospholipid measurementblood triglyceride level (CMO:0000118)82008414520084146Human
407258897GWAS907873_Htriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS907873 (human)3e-09triglycerides:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)82008414520084146Human
1558703SCL6_HSerum cholesterol level QTL 1 (human)1.2Lipid levelHDL cholesterol81246863538468635Human
407184509GWAS833485_Htriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS833485 (human)1e-08triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)82008414520084146Human
407331709GWAS980685_Hvery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS980685 (human)6e-11very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)82008414520084146Human
407261660GWAS910636_Hlow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS910636 (human)2e-08very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)82008414520084146Human
407284442GWAS933418_Hphospholipids:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS933418 (human)2e-09phospholipids:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)82008414520084146Human
407282171GWAS931147_Hcholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS931147 (human)5e-10cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)82008414520084146Human
407244184GWAS893160_Hcholesteryl ester measurement, high density lipoprotein cholesterol measurement QTL GWAS893160 (human)7e-11blood lipid amount (VT:0003949)blood high density lipoprotein cholesterol level (CMO:0000052)82008414520084146Human
407314840GWAS963816_Hvery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS963816 (human)5e-09very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)82008414520084146Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS698329_H GCST90270116 Multi-trait sex score 161,906 European ancestry females ? NR 3E-8 7.523 rs75662196 N/A sexual dimorphism measurement (EFO:0021796)
 PMID:37277458
GWAS800632_H GCST010242 HDL cholesterol levels 403,943 European ancestry individuals G 0.97206 9E-31 30.046 rs75662196 0.067763 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:32203549
GWAS833485_H GCST90092867 Triglycerides to total lipids ratio in large LDL 115,082 European ancestry individuals G 0.972162 1E-8 8 rs75662196 0.071009 triglycerides:total lipids ratio (EFO:0020947)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS836440_H GCST90092857 Cholesterol to total lipids ratio in large LDL 115,082 European ancestry individuals G 0.972162 8E-9 8.097 rs75662196 0.0718663 cholesterol:total lipids ratio (EFO:0020943)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS842780_H GCST90092861 Free cholesterol to total lipids ratio in large LDL 115,082 European ancestry individuals G 0.972162 1E-9 9 rs75662196 0.0739797 low density lipoprotein cholesterol measurement (EFO:0004611)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
GWAS888350_H GCST90092842 Triglycerides to total lipids ratio in IDL 115,082 European ancestry individuals G 0.972162 4E-10 9.398 rs75662196 0.0769052 triglycerides:total lipids ratio (EFO:0020947)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS893160_H GCST90092823 Cholesteryl ester levels in HDL 115,082 European ancestry individuals G 0.972162 7E-11 10.155 rs75662196 0.0749904 cholesteryl ester measurement (EFO:0010351)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS907873_H GCST90092903 Triglycerides to total lipids ratio in medium HDL 115,082 European ancestry individuals G 0.972162 3E-9 8.523 rs75662196 0.0723632 triglycerides:total lipids ratio (EFO:0020947)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS910636_H GCST90092909 Free cholesterol to total lipids ratio in medium LDL 115,082 European ancestry individuals G 0.972162 2E-8 7.699 rs75662196 0.0691478 low density lipoprotein cholesterol measurement (EFO:0004611)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
GWAS917970_H GCST90092832 Cholesterol to total lipids ratio in IDL 115,082 European ancestry individuals G 0.972162 9E-10 9.046 rs75662196 0.0763121 cholesterol:total lipids ratio (EFO:0020943)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS931147_H GCST90092893 Cholesterol to total lipids ratio in medium HDL 115,082 European ancestry individuals G 0.972162 5E-10 9.302 rs75662196 0.075604 cholesterol:total lipids ratio (EFO:0020943)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90092895 Cholesteryl esters to total lipids ratio in medium HDL 115,082 European ancestry individuals G 0.972162 2E-8 7.699 rs75662196 0.0690387 cholesteryl esters:total lipids ratio (EFO:0020944)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90092897 Free cholesterol to total lipids ratio in medium HDL 115,082 European ancestry individuals G 0.972162 1E-9 9 rs75662196 0.0693012 free cholesterol:total lipids ratio (EFO:0020945)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS933418_H GCST90092901 Phospholipids to total lipids ratio in medium HDL 115,082 European ancestry individuals G 0.972162 2E-9 8.699 rs75662196 0.0731114 phospholipids:total lipids ratio (EFO:0020946)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS957234_H GCST90092822 HDL cholesterol levels 115,082 European ancestry individuals G 0.972162 1E-10 10 rs75662196 0.0735076 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90093039 Triglycerides to total lipids ratio in very small VLDL 115,082 European ancestry individuals G 0.972162 1E-8 8 rs75662196 0.0693135 triglycerides:total lipids ratio (EFO:0020947)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS963816_H GCST90092973 Free cholesterol to total lipids ratio in small VLDL 115,082 European ancestry individuals G 0.972162 5E-9 8.302 rs75662196 0.0712773 very low density lipoprotein cholesterol measurement (EFO:0008317)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
GWAS965841_H GCST90092955 Triglycerides to total lipids ratio in small HDL 115,082 European ancestry individuals G 0.972162 2E-10 9.699 rs75662196 0.077592 triglycerides:total lipids ratio (EFO:0020947)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90092977 Phospholipids to total lipids ratio in small VLDL 115,082 European ancestry individuals G 0.972162 2E-8 7.699 rs75662196 0.0684968 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:35213538
None Available GCST90093029 Cholesterol to total lipids ratio in very small VLDL 115,082 European ancestry individuals G 0.972162 2E-10 9.699 rs75662196 0.0770738 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesterol:total lipids ratio (EFO:0020943)
 PMID:35213538
None Available GCST90092967 Triglycerides to total lipids ratio in small LDL 115,082 European ancestry individuals G 0.972162 3E-8 7.523 rs75662196 0.068495 triglycerides:total lipids ratio (EFO:0020947)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS978981_H GCST90092983 Ratio of triglycerides to phosphoglycerides 115,006 European ancestry individuals G 0.972157 7E-9 8.155 rs75662196 0.0688912 triglyceride measurement (EFO:0004530)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS980685_H GCST90093031 Cholesteryl esters to total lipids ratio in very small VLDL 115,082 European ancestry individuals G 0.972162 6E-11 10.222 rs75662196 0.0784895 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:35213538
Database Acc Id Source(s)
GWAS Catalog GCST90092832 GWAS Catalog

RGD Curation Notes
Note Type Note Reference