GWAS917965_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS917965_H (brain measurement QTL GWAS917965 (human)) Homo sapiens

Symbol: GWAS917965_H
Name: brain measurement QTL GWAS917965 (human)
RGD ID: 407268989
Trait: brain measurement
Measurement Type: brain measurement   (CMO:0000911)    
LOD Score: Not Available
P Value: 2.0E-27
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381689,926,205 - 89,926,206RGD_MAPPER_PIPELINEGRCh38
GRCh371689,992,613 - 89,992,614RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS917965_HHumanbrain measurement  IAGPrs111398992405850206Based on the EFO term IDGWAS_CATALOGPMID:35505052

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS917965_HHumanbrain measurement  IAGPrs111398992405850206 GWAS_CATALOGPMID:35505052
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1347965TUBB3tubulin beta 3 class III168992192589936097Human
155750692LOC127885248H3K4me1 hESC enhancer GRCh37_chr16:89991680-89992580168992527289926598Human

Position Markers

Peak: (rs111398992)
Human AssemblyChrPosition (strand)Source
GRCh381689,926,205 - 89,926,206RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407247958GWAS896934_Hcortical thickness QTL GWAS896934 (human)1e-17cortical thickness168992620589926206Human
406967847GWAS616823_Hbrain connectivity measurement QTL GWAS616823 (human)4e-15brain connectivity measurement168992620589926206Human
407311712GWAS960688_Hneuroimaging measurement QTL GWAS960688 (human)8e-23neuroimaging measurement168992620589926206Human
406985109GWAS634085_Hcortical surface area measurement, neuroimaging measurement QTL GWAS634085 (human)6e-11cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)168992620589926206Human
406968009GWAS616985_Hbrain connectivity measurement QTL GWAS616985 (human)6e-44brain connectivity measurement168992620589926206Human
406982059GWAS631035_Hbrain measurement, neuroimaging measurement QTL GWAS631035 (human)2e-15brain measurement, neuroimaging measurementbrain measurement (CMO:0000911)168992620589926206Human
407268989GWAS917965_Hbrain measurement QTL GWAS917965 (human)2e-27brain measurementbrain measurement (CMO:0000911)168992620589926206Human
407265757GWAS914733_Hbrain measurement QTL GWAS914733 (human)6e-15brain measurementbrain measurement (CMO:0000911)168992620589926206Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS616823_H GCST90165317 Node-level brain connectivity (multivariate analysis) 30,810 British ancestry individuals G 0.866335 4E-15 14.398 rs111398992 7.8508654 brain connectivity measurement (EFO:0005210)
 PMID:36800424
GWAS616985_H GCST90165318 Edge-level brain connectivity (multivariate analysis) 30,810 British ancestry individuals G 0.866335 6E-44 43.222 rs111398992 13.901516 brain connectivity measurement (EFO:0005210)
 PMID:36800424
GWAS631035_H GCST010703 Brain morphology (MOSTest) 26,502 European ancestry individuals ? NR 2E-15 14.699 rs111398992 N/A brain measurement (EFO:0004464)
neuroimaging measurement (EFO:0004346)
 PMID:32665545
GWAS634085_H GCST010701 Cortical surface area (MOSTest) 26,502 European ancestry individuals ? NR 6E-11 10.222 rs111398992 N/A cortical surface area measurement (EFO:0010736)
neuroimaging measurement (EFO:0004346)
 PMID:32665545
GWAS896934_H GCST90091061 Cortical thickness 35,657 White British ancestry individuals T 0.1325 1E-17 17 rs111398992 N/A cortical thickness (EFO:0004840)
 PMID:34560273
GWAS914733_H GCST90010427 Left–right brain asymmetry 32,256 European ancestry individuals T 0.13 6E-15 14.222 rs111398992 N/A brain measurement (EFO:0004464)
 PMID:33723403
GWAS917965_H GCST90131904 Whole brain restricted isotropic diffusion (multivariate analysis) 23,543 European ancestry individuals ? NR 2E-27 26.699 rs111398992 N/A brain measurement (EFO:0004464)
 PMID:35505052
GWAS960688_H GCST90239729 Brain morphology (MOSTest) 33,735 white British ancestry individuals ? NR 8E-23 22.097 rs111398992 N/A neuroimaging measurement (EFO:0004346)
 PMID:35164939
Database Acc Id Source(s)
GWAS Catalog GCST90131904 GWAS Catalog

RGD Curation Notes
Note Type Note Reference