GWAS907131_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS907131_H (liver fibrosis measurement QTL GWAS907131 (human)) Homo sapiens

Symbol: GWAS907131_H
Name: liver fibrosis measurement QTL GWAS907131 (human)
RGD ID: 407258155
Trait: liver integrity trait   (VT:0010547)    
Measurement Type: liver fibrotic lesion measurement   (CMO:0001088)    
LOD Score: Not Available
P Value: 2.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381916,092,494 - 16,092,495RGD_MAPPER_PIPELINEGRCh38
GRCh371916,203,304 - 16,203,305RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS907131_HHumanliver fibrotic lesion measurement  IAGPrs73517714405850206Based on the EFO term IDGWAS_CATALOGPMID:32561361

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS907131_HHumanliver integrity trait  IAGPrs73517714405850206Based on the EFO term IDGWAS_CATALOGPMID:32561361

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS907131_HHumanliver fibrosis measurement  IAGPrs73517714405850206 GWAS_CATALOGPMID:32561361
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
736665TPM4tropomyosin 4191606753816103002Human

Position Markers

Peak: (rs73517714)
Human AssemblyChrPosition (strand)Source
GRCh381916,092,494 - 16,092,495RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300034BP50_HBlood pressure QTL 50 (human)2.10.00094Blood pressuresystolic191108946337089463Human
407018067GWAS667043_Hmean platelet volume QTL GWAS667043 (human)3e-23mean platelet volumemean platelet volume (CMO:0001348)191609249416092495Human
407236263GWAS885239_Hplatelet count QTL GWAS885239 (human)3e-55platelet quantity (VT:0003179)platelet count (CMO:0000029)191609249416092495Human
407262005GWAS910981_Hliver fibrosis measurement QTL GWAS910981 (human)0.0000007liver integrity trait (VT:0010547)liver fibrotic lesion measurement (CMO:0001088)191609249416092495Human
407185792GWAS834768_Hplatelet measurement QTL GWAS834768 (human)7e-17platelet measurementplatelet measurement (CMO:0000921)191609249416092495Human
407206850GWAS855826_Hplatelet count QTL GWAS855826 (human)3e-16platelet quantity (VT:0003179)platelet count (CMO:0000029)191609249416092495Human
407264350GWAS913326_Hliver fibrosis measurement QTL GWAS913326 (human)3e-12liver integrity trait (VT:0010547)liver fibrotic lesion measurement (CMO:0001088)191609249416092495Human
407258155GWAS907131_Hliver fibrosis measurement QTL GWAS907131 (human)2e-09liver integrity trait (VT:0010547)liver fibrotic lesion measurement (CMO:0001088)191609249416092495Human
407206602GWAS855578_Hplatelet count QTL GWAS855578 (human)2e-12platelet quantity (VT:0003179)platelet count (CMO:0000029)191609249416092495Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS667043_H GCST90002345 Mean platelet volume 10,737 African American or Afro-Caribbean and African ancestry individuals C 0.908086 3E-23 22.523 rs73517714 0.253391 mean platelet volume (EFO:0004584)
 PMID:32888493
GWAS834768_H GCST90281196 Platelet side fluorescence distribution width 29,552 European ancestry individuals A 0.0222 7E-17 16.155 rs73517714 0.245916 platelet measurement (EFO:0005036)
 PMID:37596262
GWAS855578_H GCST90026509 Platelet count 16,201 African American or Afro-Caribbean individuals A 0.9195 2E-12 11.699 rs73517714 0.1555 platelet count (EFO:0004309)
 PMID:34107879
GWAS855826_H GCST90026525 Platelet count 27,236 European ancestry individuals A 0.9659 3E-16 15.523 rs73517714 0.2215 platelet count (EFO:0004309)
 PMID:34107879
GWAS885239_H GCST90094627 Platelet count 14,392 African American individuals, 13,985 Hispanic or Latin American individuals, 32,129 European ancestry individuals, 681 East Asian ancestry individuals, 13 individuals A 0.041185 3E-55 54.523 rs73517714 15.175737 platelet count (EFO:0004309)
 PMID:34553764
GWAS907131_H GCST90011736 Fibrosis-4 index in high alcohol intake 33,324 British ancestry individuals ? 0.01675 2E-9 8.699 rs73517714 0.02537 liver fibrosis measurement (EFO:0010576)
 PMID:32561361
GWAS910981_H GCST90011735 Aspartate aminotransferase platelet ratio index in high alcohol intake 33,330 British ancestry individuals ? 0.01675 7E-7 6.155 rs73517714 0.026 liver fibrosis measurement (EFO:0010576)
 PMID:32561361
GWAS913326_H GCST90011734 Forns index in high alcohol intake 33,437 British ancestry individuals ? 0.01675 3E-12 11.523 rs73517714 0.01258 liver fibrosis measurement (EFO:0010576)
 PMID:32561361
Database Acc Id Source(s)
GWAS Catalog GCST90011736 GWAS Catalog

RGD Curation Notes
Note Type Note Reference