GWAS858969_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS858969_H (leukocyte count QTL GWAS858969 (human)) Homo sapiens

Symbol: GWAS858969_H
Name: leukocyte count QTL GWAS858969 (human)
RGD ID: 407209993
Trait: leukocyte quantity   (VT:0000217)    
Measurement Type: white blood cell count   (CMO:0000027)    
LOD Score: Not Available
P Value: 2.0E-23
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381735,470,352 - 35,470,353RGD_MAPPER_PIPELINEGRCh38
GRCh371733,797,371 - 33,797,372RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS858969_HHumanwhite blood cell count  IAGPrs9916257405850206Based on the EFO term IDGWAS_CATALOGPMID:32929287

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS858969_HHumanleukocyte quantity  IAGPrs9916257405850206Based on the EFO term IDGWAS_CATALOGPMID:32929287

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS858969_HHumanleukocyte count  IAGPrs9916257405850206 GWAS_CATALOGPMID:32929287
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2291763SLFN12Lschlafen family member 12 like173546425435537678Human

Position Markers

Peak: (rs9916257)
Human AssemblyChrPosition (strand)Source
GRCh381735,470,352 - 35,470,353RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407208613GWAS857589_Hleukocyte count QTL GWAS857589 (human)2e-09leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)173547035235470353Human
407209716GWAS858692_Hleukocyte count QTL GWAS858692 (human)1e-15leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)173547035235470353Human
407269396GWAS918372_Hleukocyte count QTL GWAS918372 (human)6e-09leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)173547035235470353Human
1298406BP16_HBlood pressure QTL 16 (human)0.0004Blood pressurehypertension susceptibility171477864740778647Human
407209714GWAS858690_Hleukocyte count QTL GWAS858690 (human)9e-17leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)173547035235470353Human
407209997GWAS858973_Hleukocyte count QTL GWAS858973 (human)7e-09leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)173547035235470353Human
407209710GWAS858686_Hleukocyte count QTL GWAS858686 (human)1e-12leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)173547035235470353Human
407267213GWAS916189_Hmyeloid white cell count QTL GWAS916189 (human)2e-08myeloid white cell countwhite blood cell count (CMO:0000027)173547035235470353Human
407209993GWAS858969_Hleukocyte count QTL GWAS858969 (human)2e-23leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)173547035235470353Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS857589_H GCST90001633 CD8dim Natural Killer T Absolute Count 3,652 Sardinian (founder/genetic isolate) ancestry individuals T 0.56837 2E-9 8.699 rs9916257 0.1472 leukocyte count (EFO:0004308)
 PMID:32929287
GWAS858686_H GCST90001643 B cell %CD3- lymphocyte 3,669 Sardinian (founder/genetic isolate) ancestry individuals T 0.56846 1E-12 12 rs9916257 0.1693 leukocyte count (EFO:0004308)
 PMID:32929287
GWAS858690_H GCST90001645 Natural Killer Absolute Count 3,653 Sardinian (founder/genetic isolate) ancestry individuals T 0.5684899999999999 9E-17 16.046 rs9916257 0.2005 leukocyte count (EFO:0004308)
 PMID:32929287
GWAS858692_H GCST90001646 Natural Killer %CD3- lymphocyte 3,669 Sardinian (founder/genetic isolate) ancestry individuals T 0.56846 1E-15 15 rs9916257 0.1909 leukocyte count (EFO:0004308)
 PMID:32929287
GWAS858969_H GCST90001647 Natural Killer %lymphocyte 3,669 Sardinian (founder/genetic isolate) ancestry individuals T 0.56846 2E-23 22.699 rs9916257 0.2323 leukocyte count (EFO:0004308)
 PMID:32929287
GWAS858973_H GCST90001649 HLA DR+ Natural Killer %Natural Killer 3,596 Sardinian (founder/genetic isolate) ancestry individuals T 0.5697099999999999 7E-9 8.155 rs9916257 0.1457 leukocyte count (EFO:0004308)
 PMID:32929287
None Available GCST90001604 T cell %lymphocyte 3,669 Sardinian (founder/genetic isolate) ancestry individuals T 0.56846 1E-15 15 rs9916257 0.1918 leukocyte count (EFO:0004308)
 PMID:32929287
GWAS916189_H GCST90001522 CD33- HLA DR- Absolute Count 1,858 Sardinian (founder/genetic isolate) ancestry individuals T 0.42628 2E-8 7.699 rs9916257 0.1904 myeloid white cell count (EFO:0007988)
 PMID:32929287
GWAS918372_H GCST90001635 CD8dim Natural Killer T %lymphocyte 3,668 Sardinian (founder/genetic isolate) ancestry individuals T 0.56835 6E-9 8.222 rs9916257 0.1437 leukocyte count (EFO:0004308)
 PMID:32929287
None Available GCST90001640 CD3- lymphocyte %lymphocyte 3,669 Sardinian (founder/genetic isolate) ancestry individuals T 0.56846 1E-15 15 rs9916257 0.1918 leukocyte count (EFO:0004308)
 PMID:32929287
Database Acc Id Source(s)
GWAS Catalog GCST90001647 GWAS Catalog

RGD Curation Notes
Note Type Note Reference