GWAS857594_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS857594_H (leukocyte count QTL GWAS857594 (human)) Homo sapiens

Symbol: GWAS857594_H
Name: leukocyte count QTL GWAS857594 (human)
RGD ID: 407208618
Trait: leukocyte quantity   (VT:0000217)    
Measurement Type: white blood cell count   (CMO:0000027)    
LOD Score: Not Available
P Value: 2.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381735,467,678 - 35,467,679RGD_MAPPER_PIPELINEGRCh38
GRCh371733,794,697 - 33,794,698RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS857594_HHumanwhite blood cell count  IAGPrs9896155405850206Based on the EFO term IDGWAS_CATALOGPMID:32929287

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS857594_HHumanleukocyte quantity  IAGPrs9896155405850206Based on the EFO term IDGWAS_CATALOGPMID:32929287

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS857594_HHumanleukocyte count  IAGPrs9896155405850206 GWAS_CATALOGPMID:32929287
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2291763SLFN12Lschlafen family member 12 like173546425435537678Human

Position Markers

Peak: (rs9896155)
Human AssemblyChrPosition (strand)Source
GRCh381735,467,678 - 35,467,679RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407264276GWAS913252_Hlymphocyte count QTL GWAS913252 (human)6e-12lymphocyte countblood lymphocyte count (CMO:0000031)173546767835467679Human
1298406BP16_HBlood pressure QTL 16 (human)0.0004Blood pressurehypertension susceptibility171477864740778647Human
407267535GWAS916511_Hlymphocyte count QTL GWAS916511 (human)6e-10lymphocyte countblood lymphocyte count (CMO:0000031)173546767835467679Human
407264075GWAS913051_Hleukocyte count QTL GWAS913051 (human)8e-09leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)173546767835467679Human
407208618GWAS857594_Hleukocyte count QTL GWAS857594 (human)2e-08leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)173546767835467679Human
407211994GWAS860970_Hlymphocyte count QTL GWAS860970 (human)3e-09lymphocyte countblood lymphocyte count (CMO:0000031)173546767835467679Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS857594_H GCST90001613 CD4-CD8- T cell %leukocyte 3,668 Sardinian (founder/genetic isolate) ancestry individuals G 0.67415 2E-8 7.699 rs9896155 0.1408 leukocyte count (EFO:0004308)
 PMID:32929287
GWAS860970_H GCST90001569 Effector Memory CD4-CD8- T cell Absolute Count 3,395 Sardinian (founder/genetic isolate) ancestry individuals G 0.67416 3E-9 8.523 rs9896155 0.1522 lymphocyte count (EFO:0004587)
 PMID:32929287
GWAS913051_H GCST90001598 CD4-CD8- T cell Absolute Count 3,652 Sardinian (founder/genetic isolate) ancestry individuals G 0.6740900000000001 8E-9 8.097 rs9896155 0.1433 leukocyte count (EFO:0004308)
 PMID:32929287
GWAS913252_H GCST90001654 CD28- CD4-CD8- T cell Absolute Count 3,408 Sardinian (founder/genetic isolate) ancestry individuals G 0.67452 6E-12 11.222 rs9896155 0.1857 lymphocyte count (EFO:0004587)
 PMID:32929287
GWAS916511_H GCST90001694 CD28- CD4-CD8- T cell %T cell 3,440 Sardinian (founder/genetic isolate) ancestry individuals G 0.67435 6E-10 9.222 rs9896155 0.1701 lymphocyte count (EFO:0004587)
 PMID:32929287
Database Acc Id Source(s)
GWAS Catalog GCST90001613 GWAS Catalog

RGD Curation Notes
Note Type Note Reference