GWAS838672_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS838672_H (triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement QTL GWAS838672 (human)) Homo sapiens

Symbol: GWAS838672_H
Name: triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement QTL GWAS838672 (human)
RGD ID: 407189696
Trait: triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement
Measurement Type: blood lipoprotein measurement   (CMO:0002690)    
blood very low density lipoprotein cholesterol level   (CMO:0000648)    
LOD Score: Not Available
P Value: 2.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381666,937,877 - 66,937,878RGD_MAPPER_PIPELINEGRCh38
GRCh371666,971,780 - 66,971,781RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS838672_HHumanblood lipoprotein measurement  IAGPrs28382814405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538
GWAS838672_HHumanblood very low density lipoprotein cholesterol level  IAGPrs28382814405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Experimental Factor Annotations    Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
736535CES2carboxylesterase 2166693447166945096Human

Position Markers

Peak: (rs28382814)
Human AssemblyChrPosition (strand)Source
GRCh381666,937,877 - 66,937,878RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407167303GWAS816279_Hhigh density lipoprotein cholesterol measurement QTL GWAS816279 (human)5e-14high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)166693787766937878Human
407265893GWAS914869_Hhigh density lipoprotein particle size measurement QTL GWAS914869 (human)2e-09high density lipoprotein particle size measurementblood high density lipoprotein particle diameter (CMO:0002692)166693787766937878Human
407189696GWAS838672_Htriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement QTL GWAS838672 (human)2e-08lipoprotein measurementblood lipoprotein measurement (CMO:0002690)166693787766937878Human
407239776GWAS888752_Hapolipoprotein A 1 measurement QTL GWAS888752 (human)4e-08apolipoprotein A 1 measurementblood apolipoprotein AI level (CMO:0000520)166693787766937878Human
407188898GWAS837874_Hlow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS837874 (human)1e-14total cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)166693787766937878Human
407198412GWAS847388_Hfree cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS847388 (human)2e-12free cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)166693787766937878Human
407165710GWAS814686_Hcholesteryl ester measurement, high density lipoprotein cholesterol measurement QTL GWAS814686 (human)3e-15blood lipid amount (VT:0003949)blood high density lipoprotein cholesterol level (CMO:0000052)166693787766937878Human
407191374GWAS840350_Hphospholipid measurement, high density lipoprotein cholesterol measurement QTL GWAS840350 (human)4e-11phospholipid measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)166693787766937878Human
407191758GWAS840734_Hlow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS840734 (human)5e-15low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)166693787766937878Human
407195177GWAS844153_Hlipid measurement, high density lipoprotein cholesterol measurement QTL GWAS844153 (human)1e-12free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)166693787766937878Human
407282824GWAS931800_Hfree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS931800 (human)4e-16free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)166693787766937878Human
407308424GWAS957400_Hhigh density lipoprotein cholesterol measurement QTL GWAS957400 (human)9e-14high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)166693787766937878Human
407193428GWAS842404_Hcholesterol:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS842404 (human)6e-11cholesterol:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)166693787766937878Human
407343286GWAS992262_Hcholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS992262 (human)6e-13cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)166693787766937878Human
407244183GWAS893159_Hcholesteryl ester measurement, high density lipoprotein cholesterol measurement QTL GWAS893159 (human)6e-14blood lipid amount (VT:0003949)blood high density lipoprotein cholesterol level (CMO:0000052)166693787766937878Human
407242226GWAS891202_Hlipid measurement, high density lipoprotein cholesterol measurement QTL GWAS891202 (human)3e-09lipid measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)166693787766937878Human
407183474GWAS832450_Hvery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS832450 (human)1e-08free cholesterol measurement, high density lipoprotein cholesterol measurementblood cholesterol level (CMO:0002280)166693787766937878Human
407282111GWAS931087_Hcholesteryl ester measurement, high density lipoprotein cholesterol measurement QTL GWAS931087 (human)5e-09blood lipid amount (VT:0003949)blood total cholesterol level (CMO:0000051)166693787766937878Human
407320763GWAS969739_Hfree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS969739 (human)2e-15free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)166693787766937878Human
407344729GWAS993705_Hhigh density lipoprotein cholesterol measurement QTL GWAS993705 (human)3e-11high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)166693787766937878Human
407243064GWAS892040_Hfree cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS892040 (human)7e-12free cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)166693787766937878Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS814686_H GCST90092846 Cholesteryl ester levels in large HDL 115,082 European ancestry individuals C 0.957675 3E-15 14.523 rs28382814 0.0723628 cholesteryl ester measurement (EFO:0010351)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS816279_H GCST90092851 Concentration of large HDL particles 115,082 European ancestry individuals C 0.957675 5E-14 13.302 rs28382814 0.0686457 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS832450_H GCST90092877 Phospholipids to total lipids ratio in large VLDL 115,071 European ancestry individuals C 0.95767 1E-8 8 rs28382814 0.0575693 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:35213538
GWAS837874_H GCST90092865 Phospholipids to total lipids ratio in large LDL 115,082 European ancestry individuals C 0.957675 1E-14 14 rs28382814 0.0802947 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:35213538
GWAS838672_H GCST90092879 Triglycerides to total lipids ratio in large VLDL 115,071 European ancestry individuals C 0.95767 2E-8 7.699 rs28382814 0.057908 triglycerides:total lipids ratio (EFO:0020947)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS840350_H GCST90092852 Phospholipid levels in large HDL 115,082 European ancestry individuals C 0.957675 4E-11 10.398 rs28382814 0.0603367 phospholipid measurement (EFO:0004639)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS840734_H GCST90092859 Cholesteryl esters to total lipids ratio in large LDL 115,082 European ancestry individuals C 0.957675 5E-15 14.302 rs28382814 0.081796 low density lipoprotein cholesterol measurement (EFO:0004611)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:35213538
GWAS842404_H GCST90092857 Cholesterol to total lipids ratio in large LDL 115,082 European ancestry individuals C 0.957675 6E-11 10.222 rs28382814 0.0663692 cholesterol:total lipids ratio (EFO:0020943)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS844153_H GCST90092850 Total lipid levels in large HDL 115,082 European ancestry individuals C 0.957675 1E-12 12 rs28382814 0.0647993 lipid measurement (EFO:0004529)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS847388_H GCST90092848 Free cholesterol levels in large HDL 115,082 European ancestry individuals C 0.957675 2E-12 11.699 rs28382814 0.0638804 free cholesterol measurement (EFO:0008591)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS888752_H GCST90092808 Apolipoprotein A1 levels 115,082 European ancestry individuals C 0.957675 4E-8 7.398 rs28382814 0.0523161 apolipoprotein A 1 measurement (EFO:0004614)
 PMID:35213538
GWAS891202_H GCST90092825 Total lipid levels in HDL 115,082 European ancestry individuals C 0.957675 3E-9 8.523 rs28382814 0.0554345 lipid measurement (EFO:0004529)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS892040_H GCST90092824 Free cholesterol levels in HDL 115,082 European ancestry individuals C 0.957675 7E-12 11.155 rs28382814 0.0632909 free cholesterol measurement (EFO:0008591)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS893159_H GCST90092823 Cholesteryl ester levels in HDL 115,082 European ancestry individuals C 0.957675 6E-14 13.222 rs28382814 0.0702286 cholesteryl ester measurement (EFO:0010351)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90092826 Concentration of HDL particles 115,082 European ancestry individuals C 0.957675 1E-8 8 rs28382814 0.0556956 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS914869_H GCST90092828 Average diameter for HDL particles 115,082 European ancestry individuals C 0.957675 2E-9 8.699 rs28382814 0.0553991 high density lipoprotein particle size measurement (EFO:0008592)
 PMID:35213538
None Available GCST90092844 Cholesterol levels in large HDL 115,082 European ancestry individuals C 0.957675 1E-14 14 rs28382814 0.0708467 total cholesterol measurement (EFO:0004574)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS931087_H GCST90092894 Cholesteryl ester levels in medium HDL 115,082 European ancestry individuals C 0.957675 5E-9 8.302 rs28382814 0.056263 cholesteryl ester measurement (EFO:0010351)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90092896 Free cholesterol levels in medium HDL 115,082 European ancestry individuals C 0.957675 1E-8 8 rs28382814 0.0540431 free cholesterol measurement (EFO:0008591)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS931800_H GCST90092897 Free cholesterol to total lipids ratio in medium HDL 115,082 European ancestry individuals C 0.957675 4E-16 15.398 rs28382814 0.0750397 free cholesterol:total lipids ratio (EFO:0020945)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS957400_H GCST90092822 HDL cholesterol levels 115,082 European ancestry individuals C 0.957675 9E-14 13.046 rs28382814 0.0693337 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90092892 Cholesterol levels in medium HDL 115,082 European ancestry individuals C 0.957675 5E-9 8.302 rs28382814 0.0561003 total cholesterol measurement (EFO:0004574)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS969739_H GCST90092949 Free cholesterol to total lipids ratio in small HDL 115,082 European ancestry individuals C 0.957675 2E-15 14.699 rs28382814 0.0784675 free cholesterol:total lipids ratio (EFO:0020945)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90092990 Total concentration of lipoprotein particles 115,082 European ancestry individuals C 0.957675 2E-8 7.699 rs28382814 0.0549375 lipoprotein measurement (EFO:0004732)
 PMID:35213538
GWAS992262_H GCST90093007 Cholesteryl esters to total lipids ratio in very large HDL 115,056 European ancestry individuals C 0.957682 6E-13 12.222 rs28382814 0.0749039 cholesteryl esters:total lipids ratio (EFO:0020944)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90093009 Free cholesterol to total lipids ratio in very large HDL 115,056 European ancestry individuals C 0.957682 1E-12 12 rs28382814 0.0653896 free cholesterol:total lipids ratio (EFO:0020945)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS993705_H GCST90093011 Concentration of very large HDL particles 115,082 European ancestry individuals C 0.957675 3E-11 10.523 rs28382814 0.062564 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
Database Acc Id Source(s)
GWAS Catalog GCST90092879 GWAS Catalog
  GCST90092990 GWAS Catalog

RGD Curation Notes
Note Type Note Reference