GWAS837680_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS837680_H (Brugada syndrome QTL GWAS837680 (human)) Homo sapiens

Symbol: GWAS837680_H
Name: Brugada syndrome QTL GWAS837680 (human)
RGD ID: 407188704
Trait: Brugada syndrome
LOD Score: Not Available
P Value: 3.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381766,304,163 - 66,304,164RGD_MAPPER_PIPELINEGRCh38
GRCh371764,300,281 - 64,300,282RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS837680_HHumanBrugada syndrome  IAGPrs12945884405850206 GWAS_CATALOGPMID:35210625
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
737062PRKCAprotein kinase C alpha176630261366810743Human

Position Markers

Peak: (rs12945884)
Human AssemblyChrPosition (strand)Source
GRCh381766,304,163 - 66,304,164RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407261014GWAS909990_HBrugada syndrome QTL GWAS909990 (human)2e-08Brugada syndrome176630416366304164Human
407188704GWAS837680_HBrugada syndrome QTL GWAS837680 (human)3e-08Brugada syndrome176630416366304164Human
406899325GWAS548301_Hdiastolic blood pressure, systolic blood pressure QTL GWAS548301 (human)6e-09diastolic blood pressure, systolic blood pressuresystolic blood pressure (CMO:0000004)176630416366304164Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS548301_H GCST90239829 Blood pressure (pleiotropy model 2 SBP adjusted for estimated causal effects x DBP) 757,601 European ancestry individuals, 318,891 European ancestry, African American or Afro-Caribbean, Native American ancestry, Asian ancestry individuals ? NR 6E-9 8.222 rs12945884 0.094648615 diastolic blood pressure (EFO:0006336)
systolic blood pressure (EFO:0006335)
 PMID:34989438
GWAS837680_H GCST90086158 Brugada syndrome 2,820 European ancestry cases, 10,001 European ancestry controls T 0.53 3E-8 7.523 rs12945884 1.2 PMID:35210625
GWAS909990_H GCST90295917 Brugada syndrome 940 East Asian ancestry cases, 1,634 East Asian ancestry controls, 2,820 European ancestry cases, 10,001 European ancestry controls C 0.458 2E-8 7.699 rs12945884 0.85 PMID:38747976
Database Acc Id Source(s)
GWAS Catalog GCST90086158 GWAS Catalog

RGD Curation Notes
Note Type Note Reference