GWAS837134_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS837134_H (hypothyroidism QTL GWAS837134 (human)) Homo sapiens

Symbol: GWAS837134_H
Name: hypothyroidism QTL GWAS837134 (human)
RGD ID: 407188158
Trait: hypothyroidism
LOD Score: Not Available
P Value: 3.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381918,273,311 - 18,273,312RGD_MAPPER_PIPELINEGRCh38
GRCh371918,384,121 - 18,384,122RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
hypothyroidism  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Hypothyroidism  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1353790IQCNIQ motif containing N191825709818274452Human

Position Markers

Peak: (rs55817508)
Human AssemblyChrPosition (strand)Source
GRCh381918,273,311 - 18,273,312RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300034BP50_HBlood pressure QTL 50 (human)2.10.00094Blood pressuresystolic191108946337089463Human
407295781GWAS944757_Hhypothyroidism QTL GWAS944757 (human)5e-15hypothyroidism191827331218273313Human
407188158GWAS837134_Hhypothyroidism QTL GWAS837134 (human)3e-10hypothyroidism191827331118273312Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS837134_H GCST90018862 Hypothyroidism 30,155 European ancestry cases, 379,986 European ancestry controls, 1,114 East Asian ancestry cases, 172,656 East Asian ancestry controls T NR 3E-10 9.523 rs55817508 0.0766 hypothyroidism (EFO:0004705)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST90018862 GWAS Catalog

RGD Curation Notes
Note Type Note Reference