GWAS836273_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS836273_H (Inguinal hernia QTL GWAS836273 (human)) Homo sapiens

Symbol: GWAS836273_H
Name: Inguinal hernia QTL GWAS836273 (human)
RGD ID: 407187297
Trait: Inguinal hernia
LOD Score: Not Available
P Value: 1.0E-27
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381132,437,261 - 32,437,262RGD_MAPPER_PIPELINEGRCh38
GRCh371132,458,807 - 32,458,808RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS836273_HHumanInguinal hernia  IAGPrs3809060405850206 GWAS_CATALOGPMID:34594039
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
38601292LOC107982234WT1/WT1-AS bi-directional promoter region113243016932437423Human
1605386WT1-ASWT1 antisense RNA113243551832458769Human

Position Markers

Peak: (rs3809060)
Human AssemblyChrPosition (strand)Source
GRCh381132,437,261 - 32,437,262RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576345LVC1_HLeft ventricular contractility QTL 1 (human)3.93Left ventricular contractility11797076733970767Human
406921813GWAS570789_HAntihypertensive use measurement QTL GWAS570789 (human)5e-21Antihypertensive use measurement113243726132437262Human
407187297GWAS836273_HInguinal hernia QTL GWAS836273 (human)1e-27Inguinal hernia113243726132437262Human
406900662GWAS549638_Hvisceral:abdominal adipose tissue ratio measurement QTL GWAS549638 (human)6e-09visceral:abdominal adipose tissue ratio measurement113243726132437262Human
407131314GWAS780290_HInguinal hernia QTL GWAS780290 (human)4e-14Inguinal hernia113243726132437262Human
1559104SCL15_HSerum cholesterol level QTL 15 (human)2.60.06Lipid levelhyperlipidemia susceptibility111589236841892368Human
407293758GWAS942734_HInguinal hernia QTL GWAS942734 (human)1e-22Inguinal hernia113243726132437262Human
407273438GWAS922414_Hpelvic organ prolapse QTL GWAS922414 (human)0.0000008pelvic organ prolapse113243726132437262Human
407339981GWAS988957_Hcardiovascular disease QTL GWAS988957 (human)4e-08cardiovascular disease113243726132437262Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS549638_H GCST90205224 Visceral adipose tissue volumes to abdominal adipose tissue volumes ratio 19,981 European ancestry, East Asian ancestry, South Asian ancestry, African ancestry, NR ancestry females G 0.619 6E-9 8.222 rs3809060 0.057 visceral:abdominal adipose tissue ratio measurement (EFO:0803318)
 PMID:35773277
GWAS570789_H GCST90250905 Medication use for hypertension (number of purchases) 567,671 European ancestry individuals ? NR 5E-21 20.302 rs3809060 0.013946 Antihypertensive use measurement (EFO:0009927)
 PMID:36653479
GWAS780290_H GCST003198 Inguinal hernia 5,295 European ancestry cases, 67,510 European ancestry controls G 0.63 4E-14 13.398 rs3809060 1.11 Inguinal hernia (HP:0000023)
 PMID:26686553
GWAS836273_H GCST90018868 Inguinal hernia 16,725 European ancestry cases, 428,356 European ancestry controls, 1,664 East Asian ancestry cases, 177,062 East Asian ancestry controls T NR 1E-27 27 rs3809060 0.1289 Inguinal hernia (HP:0000023)
 PMID:34594039
GWAS922414_H GCST010174 Pelvic organ prolapse 15,010 European ancestry cases, 340,734 European ancestry controls G 0.63 8E-7 6.097 rs3809060 1.07 pelvic organ prolapse (EFO:0004710)
 PMID:32184442
GWAS942734_H GCST90027168 Inguinal hernia 13,047 European ancestry cases, 262,499 European ancestry controls G 0.62 1E-22 22 rs3809060 1.12 Inguinal hernia (HP:0000023)
 PMID:34382107
GWAS988957_H GCST007072 Cardiovascular disease approximately 459,000 European ancestry individuals ? NR 4E-8 7.398 rs3809060 N/A cardiovascular disease (EFO:0000319)
 PMID:30595370
Database Acc Id Source(s)
GWAS Catalog GCST90018868 GWAS Catalog

RGD Curation Notes
Note Type Note Reference