GWAS832383_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS832383_H (free cholesterol measurement, very low density lipoprotein cholesterol measurement QTL GWAS832383 (human)) Homo sapiens

Symbol: GWAS832383_H
Name: free cholesterol measurement, very low density lipoprotein cholesterol measurement QTL GWAS832383 (human)
RGD ID: 407183407
Trait: free cholesterol measurement, very low density lipoprotein cholesterol measurement
Measurement Type: blood cholesterol level   (CMO:0002280)    
blood very low density lipoprotein cholesterol level   (CMO:0000648)    
LOD Score: Not Available
P Value: 1.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38772,567,373 - 72,567,374RGD_MAPPER_PIPELINEGRCh38
GRCh37772,032,358 - 72,032,359RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS832383_HHumanblood cholesterol level  IAGPrs35867424405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538
GWAS832383_HHumanblood very low density lipoprotein cholesterol level  IAGPrs35867424405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS832383_HHumanfree cholesterol measurement  IAGPrs35867424405850206 GWAS_CATALOGPMID:35213538
GWAS832383_HHumanvery low density lipoprotein cholesterol measurement  IAGPrs35867424405850206 GWAS_CATALOGPMID:35213538
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs35867424)
Human AssemblyChrPosition (strand)Source
GRCh38772,567,373 - 72,567,374RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407283686GWAS932662_Hcholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS932662 (human)7e-10cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)77256737372567374Human
407240164GWAS889140_Htriglyceride measurement, intermediate density lipoprotein measurement QTL GWAS889140 (human)2e-08triglyceride measurement, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)77256737372567374Human
407314725GWAS963701_Hvery low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS963701 (human)1e-08blood lipid amount (VT:0003949)blood high density lipoprotein cholesterol level (CMO:0000052)77256737372567374Human
407181062GWAS830038_Hvery low density lipoprotein cholesterol measurement QTL GWAS830038 (human)7e-13very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)77256737372567374Human
407325186GWAS974162_Hvery low density lipoprotein cholesterol measurement QTL GWAS974162 (human)2e-13very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)77256737372567374Human
407327970GWAS976946_Hvery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS976946 (human)2e-10very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)77256737372567374Human
407282656GWAS931632_Htriglyceride measurement, low density lipoprotein cholesterol measurement QTL GWAS931632 (human)3e-09very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)77256737372567374Human
407182914GWAS831890_Hvery low density lipoprotein cholesterol measurement, phospholipid measurement QTL GWAS831890 (human)8e-13very low density lipoprotein cholesterol measurement, phospholipid measurementblood very low density lipoprotein cholesterol level (CMO:0000648)77256737372567374Human
407199010GWAS847986_Hfree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS847986 (human)2e-09total cholesterol measurement, high density lipoprotein cholesterol measurementblood total cholesterol level (CMO:0000051)77256737372567374Human
407282158GWAS931134_Hcholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS931134 (human)6e-10cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)77256737372567374Human
407183407GWAS832383_Hfree cholesterol measurement, very low density lipoprotein cholesterol measurement QTL GWAS832383 (human)1e-11free cholesterol measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)77256737372567374Human
407292203GWAS941179_Hvery low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS941179 (human)8e-10very low density lipoprotein cholesterol measurement, lipid measurementblood lipid measurement (CMO:0000050)77256737372567374Human
407194251GWAS843227_Htriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS843227 (human)3e-11triglycerides:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)77256737372567374Human
407326665GWAS975641_Hfatty acid measurement QTL GWAS975641 (human)7e-09fatty acid measurement77256737372567374Human
407254952GWAS903928_Homega-3 polyunsaturated fatty acid measurement QTL GWAS903928 (human)5e-08omega-3 polyunsaturated fatty acid measurement77256737372567374Human
407309942GWAS958918_Hchylomicron measurement, total cholesterol measurement, very low density lipoprotein cholesterol measurement QTL GWAS958918 (human)6e-13chylomicron measurement, total cholesterol measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)77256737372567374Human
407261239GWAS910215_Htriglyceride measurement, low density lipoprotein cholesterol measurement QTL GWAS910215 (human)6e-11triglyceride measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)77256737372567374Human
407184566GWAS833542_Hvery low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS833542 (human)3e-12very low density lipoprotein cholesterol measurement, lipid measurementblood lipid measurement (CMO:0000050)77256737372567374Human
407324017GWAS972993_Htriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement QTL GWAS972993 (human)2e-11free cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)77256737372567374Human
407284593GWAS933569_Htriglyceride measurement, very low density lipoprotein cholesterol measurement QTL GWAS933569 (human)1e-13very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)77256737372567374Human
407323647GWAS972623_Hvery low density lipoprotein cholesterol measurement, phospholipid measurement QTL GWAS972623 (human)7e-12blood lipid amount (VT:0003949)blood chylomicron level (CMO:0000527)77256737372567374Human
407321822GWAS970798_Hfree cholesterol measurement, very low density lipoprotein cholesterol measurement QTL GWAS970798 (human)4e-11free cholesterol measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)77256737372567374Human
407183039GWAS832015_Hvery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS832015 (human)1e-09total cholesterol measurement, very low density lipoprotein cholesterol measurementblood total cholesterol level (CMO:0000051)77256737372567374Human
407333468GWAS982444_Htriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS982444 (human)1e-15triglycerides:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)77256737372567374Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS830038_H GCST90092875 Concentration of large VLDL particles 115,082 European ancestry individuals G 0.970467 7E-13 12.155 rs35867424 0.0865587 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS831890_H GCST90092876 Phospholipid levels in large VLDL 115,082 European ancestry individuals G 0.970467 8E-13 12.097 rs35867424 0.0862342 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS832015_H GCST90092871 Cholesteryl esters to total lipids ratio in large VLDL 115,071 European ancestry individuals G 0.970472 1E-9 9 rs35867424 0.072854 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:35213538
GWAS832383_H GCST90092872 Free cholesterol levels in large VLDL 115,082 European ancestry individuals G 0.970467 1E-11 11 rs35867424 0.0821119 free cholesterol measurement (EFO:0008591)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS833542_H GCST90092874 Total lipid levels in large VLDL 115,082 European ancestry individuals G 0.970467 3E-12 11.523 rs35867424 0.0844001 very low density lipoprotein cholesterol measurement (EFO:0008317)
lipid measurement (EFO:0004529)
 PMID:35213538
None Available GCST90092868 Cholesterol levels in large VLDL 115,082 European ancestry individuals G 0.970467 1E-9 9 rs35867424 0.0742772 total cholesterol measurement (EFO:0004574)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS843227_H GCST90092855 Triglycerides to total lipids ratio in large HDL 115,082 European ancestry individuals G 0.970467 3E-11 10.523 rs35867424 0.0782657 triglycerides:total lipids ratio (EFO:0020947)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS847986_H GCST90092849 Free cholesterol to total lipids ratio in large HDL 115,082 European ancestry individuals G 0.970467 2E-9 8.699 rs35867424 0.0698927 free cholesterol:total lipids ratio (EFO:0020945)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS889140_H GCST90092841 Triglyceride levels in IDL 115,082 European ancestry individuals G 0.970467 2E-8 7.699 rs35867424 0.0685839 triglyceride measurement (EFO:0004530)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS903928_H GCST90092931 Omega-3 fatty acid levels 115,006 European ancestry individuals G 0.970469 5E-8 7.302 rs35867424 0.0654256 omega-3 polyunsaturated fatty acid measurement (EFO:0010119)
 PMID:35213538
GWAS910215_H GCST90092914 Triglyceride levels in medium LDL 115,082 European ancestry individuals G 0.970467 6E-11 10.222 rs35867424 0.0797451 triglyceride measurement (EFO:0004530)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS931134_H GCST90092893 Cholesterol to total lipids ratio in medium HDL 115,082 European ancestry individuals G 0.970467 6E-10 9.222 rs35867424 0.0734537 cholesterol:total lipids ratio (EFO:0020943)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS931632_H GCST90092890 Triglyceride levels in LDL 115,082 European ancestry individuals G 0.970467 3E-9 8.523 rs35867424 0.0726208 triglyceride measurement (EFO:0004530)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS932662_H GCST90092895 Cholesteryl esters to total lipids ratio in medium HDL 115,082 European ancestry individuals G 0.970467 7E-10 9.155 rs35867424 0.0744862 cholesteryl esters:total lipids ratio (EFO:0020944)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS933569_H GCST90092926 Triglyceride levels in medium VLDL 115,082 European ancestry individuals G 0.970467 1E-13 13 rs35867424 0.0897318 triglyceride measurement (EFO:0004530)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS941179_H GCST90092999 Total lipid levels in VLDL 115,082 European ancestry individuals G 0.970467 8E-10 9.097 rs35867424 0.0752501 very low density lipoprotein cholesterol measurement (EFO:0008317)
lipid measurement (EFO:0004529)
 PMID:35213538
GWAS958918_H GCST90093040 Cholesterol levels in chylomicrons and extremely large VLDL 115,082 European ancestry individuals G 0.970467 6E-13 12.222 rs35867424 0.086602 chylomicron measurement (EFO:0008596)
total cholesterol measurement (EFO:0004574)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS963701_H GCST90092974 Total lipid levels in small VLDL 115,082 European ancestry individuals G 0.970467 1E-8 8 rs35867424 0.0702084 very low density lipoprotein cholesterol measurement (EFO:0008317)
lipid measurement (EFO:0004529)
 PMID:35213538
None Available GCST90093004 Cholesterol levels in very large HDL 115,082 European ancestry individuals G 0.970467 2E-9 8.699 rs35867424 0.067776 total cholesterol measurement (EFO:0004574)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS970798_H GCST90093020 Free cholesterol levels in very large VLDL 115,082 European ancestry individuals G 0.970467 4E-11 10.398 rs35867424 0.0799245 free cholesterol measurement (EFO:0008591)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS972623_H GCST90093024 Phospholipid levels in very large VLDL 115,082 European ancestry individuals G 0.970467 7E-12 11.155 rs35867424 0.082608 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS972993_H GCST90093027 Triglycerides to total lipids ratio in very large VLDL 114,160 European ancestry individuals G 0.970475 2E-11 10.699 rs35867424 0.0811817 triglycerides:total lipids ratio (EFO:0020947)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS974162_H GCST90093023 Concentration of very large VLDL particles 115,082 European ancestry individuals G 0.970467 2E-13 12.699 rs35867424 0.0883961 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
None Available GCST90092966 Triglyceride levels in small LDL 115,082 European ancestry individuals G 0.970467 2E-13 12.699 rs35867424 0.0889795 triglyceride measurement (EFO:0004530)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS975641_H GCST90092987 Total fatty acid levels 115,006 European ancestry individuals G 0.970469 7E-9 8.155 rs35867424 0.0713905 fatty acid measurement (EFO:0005110)
 PMID:35213538
GWAS976946_H GCST90093021 Free cholesterol to total lipids ratio in very large VLDL 114,160 European ancestry individuals G 0.970475 2E-10 9.699 rs35867424 0.077131 very low density lipoprotein cholesterol measurement (EFO:0008317)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
None Available GCST90093016 Cholesterol levels in very large VLDL 115,082 European ancestry individuals G 0.970467 3E-9 8.523 rs35867424 0.0724797 total cholesterol measurement (EFO:0004574)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
None Available GCST90092975 Concentration of small VLDL particles 115,082 European ancestry individuals G 0.970467 3E-9 8.523 rs35867424 0.0726824 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
None Available GCST90093017 Cholesterol to total lipids ratio in very large VLDL 114,160 European ancestry individuals G 0.970475 2E-13 12.699 rs35867424 0.088228 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesterol:total lipids ratio (EFO:0020943)
 PMID:35213538
GWAS982444_H GCST90093015 Triglycerides to total lipids ratio in very large HDL 115,056 European ancestry individuals G 0.970468 1E-15 15 rs35867424 0.094062 triglycerides:total lipids ratio (EFO:0020947)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90093019 Cholesteryl esters to total lipids ratio in very large VLDL 114,160 European ancestry individuals G 0.970475 1E-13 13 rs35867424 0.0886179 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:35213538
None Available GCST90093042 Cholesteryl ester levels in chylomicrons and extremely large VLDL 115,082 European ancestry individuals G 0.970467 7E-12 11.155 rs35867424 0.0828598 cholesteryl ester measurement (EFO:0010351)
chylomicron measurement (EFO:0008596)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
None Available GCST90093006 Cholesteryl ester levels in very large HDL 115,082 European ancestry individuals G 0.970467 1E-8 8 rs35867424 0.0638987 cholesteryl ester measurement (EFO:0010351)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90093008 Free cholesterol levels in very large HDL 115,082 European ancestry individuals G 0.970467 2E-11 10.699 rs35867424 0.078597 free cholesterol measurement (EFO:0008591)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
Database Acc Id Source(s)
GWAS Catalog GCST90092872 GWAS Catalog

RGD Curation Notes
Note Type Note Reference