GWAS831148_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS831148_H (lymphocyte measurement QTL GWAS831148 (human)) Homo sapiens

Symbol: GWAS831148_H
Name: lymphocyte measurement QTL GWAS831148 (human)
RGD ID: 407182172
Trait: lymphocyte measurement
LOD Score: Not Available
P Value: 1.0E-16
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381735,487,739 - 35,487,740RGD_MAPPER_PIPELINEGRCh38
GRCh371733,814,758 - 33,814,759RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS831148_HHumanlymphocyte measurement  IAGPrs4796089405850206 GWAS_CATALOGPMID:37596262
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2291763SLFN12Lschlafen family member 12 like173546425435537678Human

Position Markers

Peak: (rs4796089)
Human AssemblyChrPosition (strand)Source
GRCh381735,487,739 - 35,487,740RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407403819GWAS1052795_Hlymphocyte count QTL GWAS1052795 (human)6e-11lymphocyte countblood lymphocyte count (CMO:0000031)173548773935487740Human
407403820GWAS1052796_Hlymphocyte count QTL GWAS1052796 (human)4e-09lymphocyte countblood lymphocyte count (CMO:0000031)173548773935487740Human
1298406BP16_HBlood pressure QTL 16 (human)0.0004Blood pressurehypertension susceptibility171477864740778647Human
407403325GWAS1052301_Hleukocyte count QTL GWAS1052301 (human)3e-09leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)173548773935487740Human
407162866GWAS811842_Hneutrophil count QTL GWAS811842 (human)2e-09neutrophil quantity (VT:0000222)blood neutrophil count (CMO:0000030)173548773935487740Human
407403327GWAS1052303_Hleukocyte count QTL GWAS1052303 (human)2e-08leukocyte quantity (VT:0000217)blood lymphocyte count (CMO:0000031)173548773935487740Human
407182172GWAS831148_Hlymphocyte measurement QTL GWAS831148 (human)1e-16lymphocyte measurement173548773935487740Human
407403828GWAS1052804_Hlymphocyte count QTL GWAS1052804 (human)1e-09lymphocyte countblood lymphocyte count (CMO:0000031)173548773935487740Human
407060637GWAS709613_Hneutrophil count QTL GWAS709613 (human)1e-11neutrophil quantity (VT:0000222)blood neutrophil count (CMO:0000030)173548773935487740Human
407400150GWAS1049126_Hlymphocyte count QTL GWAS1049126 (human)4e-10lymphocyte countblood lymphocyte count (CMO:0000031)173548773935487740Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS709613_H GCST90002351 Neutrophil count 519,288 European ancestry individuals C 0.083755 1E-11 11 rs4796089 0.023755 neutrophil count (EFO:0004833)
 PMID:32888493
GWAS811842_H GCST90002398 Neutrophil count 408,112 British individuals C 0.083095 2E-9 8.699 rs4796089 0.023877716 neutrophil count (EFO:0004833)
 PMID:32888494
GWAS831148_H GCST90281247 Lymphocyte side fluorescence 39,640 European ancestry individuals C 0.0829 1E-16 16 rs4796089 0.106427 lymphocyte measurement (EFO:0803546)
 PMID:37596262
GWAS1049126_H GCST90001662 CD28- CD8dim T cell %CD8dim T cell 3,440 Sardinian (founder/genetic isolate) ancestry individuals C 0.1343 4E-10 9.398 rs4796089 0.2283 lymphocyte count (EFO:0004587)
 PMID:32929287
GWAS1052301_H GCST90001641 CD3- lymphocyte %leukocyte 3,669 Sardinian (founder/genetic isolate) ancestry individuals C 0.13396 3E-9 8.523 rs4796089 0.2194 leukocyte count (EFO:0004308)
 PMID:32929287
GWAS1052303_H GCST90001647 Natural Killer %lymphocyte 3,669 Sardinian (founder/genetic isolate) ancestry individuals C 0.13396 2E-8 7.699 rs4796089 0.2075 leukocyte count (EFO:0004308)
 PMID:32929287
GWAS1052795_H GCST90001653 CD28- CD4-CD8- T cell %CD4-CD8- T cell 3,440 Sardinian (founder/genetic isolate) ancestry individuals C 0.1343 6E-11 10.222 rs4796089 0.2435 lymphocyte count (EFO:0004587)
 PMID:32929287
None Available GCST90001656 CD28+ CD4-CD8- T cell %CD4-CD8- T cell 3,440 Sardinian (founder/genetic isolate) ancestry individuals C 0.1343 6E-11 10.222 rs4796089 0.2435 lymphocyte count (EFO:0004587)
 PMID:32929287
GWAS1052796_H GCST90001661 CD28- CD8dim T cell %T cell 3,440 Sardinian (founder/genetic isolate) ancestry individuals C 0.1343 4E-9 8.398 rs4796089 0.2225 lymphocyte count (EFO:0004587)
 PMID:32929287
GWAS1052804_H GCST90001686 CD28- CD8+ T cell %CD8+ T cell 3,440 Sardinian (founder/genetic isolate) ancestry individuals C 0.1343 1E-9 9 rs4796089 0.2034 lymphocyte count (EFO:0004587)
 PMID:32929287
None Available GCST90001687 CD28- CD8+ T cell Absolute Count 3,408 Sardinian (founder/genetic isolate) ancestry individuals C 0.13395 2E-8 7.699 rs4796089 0.2103 lymphocyte count (EFO:0004587)
 PMID:32929287
Database Acc Id Source(s)
GWAS Catalog GCST90281247 GWAS Catalog

RGD Curation Notes
Note Type Note Reference