GWAS830689_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS830689_H (coronary artery disease QTL GWAS830689 (human)) Homo sapiens

Symbol: GWAS830689_H
Name: coronary artery disease QTL GWAS830689 (human)
RGD ID: 407181713
Trait: coronary artery disease
Measurement Type: hip circumference   (CMO:0000014)    
LOD Score: Not Available
P Value: 5.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382041,295,639 - 41,295,640RGD_MAPPER_PIPELINEGRCh38
GRCh372039,924,279 - 39,924,280RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1342474ZHX3zinc fingers and homeoboxes 3204117845541317731Human

Position Markers

Peak: (rs6102343)
Human AssemblyChrPosition (strand)Source
GRCh382041,295,639 - 41,295,640RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300007BP29_HBlood pressure QTL 29 (human)Blood pressurehypertension susceptibility203653600562536005Human
407181713GWAS830689_Hcoronary artery disease QTL GWAS830689 (human)5e-09BMI-adjusted hip circumferencehip circumference (CMO:0000014)204129563941295640Human
406979174GWAS628150_Hmyocardial infarction QTL GWAS628150 (human)2e-08myocardial infarction204129563941295640Human
407255405GWAS904381_Hmyocardial infarction QTL GWAS904381 (human)3e-08myocardial infarction204129563941295640Human
407090989GWAS739965_Hcoronary artery disease QTL GWAS739965 (human)1e-08coronary artery disease204129563941295640Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS628150_H GCST011365 Myocardial infarction 14,825 European ancestry cases, 44,000 European and unknown ancestry cases, 2,680 cases, 380,970 European ancestry controls, 123,504 European and unknown ancestry controls, 73,242 controls A 0.24257 2E-8 7.699 rs6102343 1.05 myocardial infarction (EFO:0000612)
 PMID:33532862
GWAS739965_H GCST005195 Coronary artery disease up to 122,733 cases, up to 424,528 controls A 0.2467 1E-8 8 rs6102343 0.0372 coronary artery disease (EFO:0001645)
 PMID:29212778
GWAS830689_H GCST90132314 Coronary artery disease 181,522 European ancestry, unknown cases, 984,168 European ancestry, unknown controls A 0.235 5E-9 8.302 rs6102343 1.034 coronary artery disease (EFO:0001645)
 PMID:36474045
GWAS904381_H GCST90432175 Myocardial infarction 3,950 Saudi Arabian ancestry cases, 2,324 Saudi Arabian ancestry controls, 56,278 European and unknown ancestry cases, 577,716 European and unknown ancestry controls ? NR 3E-8 7.523 rs6102343 0.9541 myocardial infarction (EFO:0000612)
 PMID:38072966
None Available GCST90020026 Hip index 219,872 British ancestry women A NR 5E-9 8.302 rs6102343 0.0202348 BMI-adjusted hip circumference (EFO:0008039)
 PMID:34021172
Database Acc Id Source(s)
GWAS Catalog GCST90020026 GWAS Catalog
  GCST90132314 GWAS Catalog

RGD Curation Notes
Note Type Note Reference