GWAS829821_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS829821_H (calcium measurement QTL GWAS829821 (human)) Homo sapiens

Symbol: GWAS829821_H
Name: calcium measurement QTL GWAS829821 (human)
RGD ID: 407180845
Trait: calcium measurement
Measurement Type: blood calcium level   (CMO:0000502)    
LOD Score: Not Available
P Value: 6.0E-30
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh384102,005,766 - 102,005,767RGD_MAPPER_PIPELINEGRCh38
GRCh374102,926,923 - 102,926,924RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS829821_HHumanblood calcium level  IAGPrs34592089405850206Based on the EFO term IDGWAS_CATALOGPMID:33462484

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS829821_HHumancalcium measurement  IAGPrs34592089405850206 GWAS_CATALOGPMID:33462484
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1342509BANK1B cell scaffold protein with ankyrin repeats 14101790730102074812Human

Position Markers

Peak: (rs34592089)
Human AssemblyChrPosition (strand)Source
GRCh384102,005,766 - 102,005,767RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407342342GWAS991318_Hattention deficit hyperactivity disorder, autism spectrum disorder, intelligence QTL GWAS991318 (human)2e-18attention deficit hyperactivity disorder, autism spectrum disorder, intelligence4102005766102005767Human
407044928GWAS693904_Hintelligence QTL GWAS693904 (human)1e-14intelligence4102005766102005767Human
407172674GWAS821650_Hserum albumin measurement QTL GWAS821650 (human)2e-24serum albumin measurementserum albumin level (CMO:0000550)4102005766102005767Human
407305184GWAS954160_Hfat body mass QTL GWAS954160 (human)1e-13body fat mass (VT:0010482)total body fat mass (CMO:0000305)4102005766102005767Human
407284289GWAS933265_Htotal cholesterol measurement QTL GWAS933265 (human)2e-23total cholesterol measurementblood total cholesterol level (CMO:0000051)4102005766102005767Human
407180845GWAS829821_Hcalcium measurement QTL GWAS829821 (human)6e-30calcium measurementblood calcium level (CMO:0000502)4102005766102005767Human
407090379GWAS739355_Hosteoarthritis, knee QTL GWAS739355 (human)7e-12osteoarthritis, knee4102005766102005767Human
407219309GWAS868285_Hintelligence QTL GWAS868285 (human)3e-16intelligence4102005766102005767Human
407299789GWAS948765_Hbody mass index QTL GWAS948765 (human)6e-21body mass indexbody mass index (BMI) (CMO:0000105)4102005766102005767Human
407152776GWAS801752_Hbrain volume measurement QTL GWAS801752 (human)7e-10brain volume measurementbrain morphological measurement (CMO:0000136)4102005766102005767Human
407161385GWAS810361_Hintelligence QTL GWAS810361 (human)1e-12intelligence4102005766102005767Human
407165993GWAS814969_Haspartate aminotransferase measurement QTL GWAS814969 (human)3e-27aspartate aminotransferase measurementblood aspartate aminotransferase activity level (CMO:0000580)4102005766102005767Human
407272616GWAS921592_Hhypertension QTL GWAS921592 (human)1e-09hypertension4102005766102005767Human
407317353GWAS966329_Hhigh density lipoprotein cholesterol measurement QTL GWAS966329 (human)3e-51high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)4102005766102005767Human
407050290GWAS699266_Hcortical thickness QTL GWAS699266 (human)3e-12cortical thickness4102005766102005767Human
407155670GWAS804646_Hbrain volume measurement QTL GWAS804646 (human)3e-13brain volume measurementbrain morphological measurement (CMO:0000136)4102005766102005767Human
407307989GWAS956965_Hlow density lipoprotein cholesterol measurement QTL GWAS956965 (human)4e-09low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)4102005766102005767Human
407339551GWAS988527_Hurate measurement QTL GWAS988527 (human)1e-10urate measurementblood uric acid level (CMO:0000501)4102005766102005767Human
407154399GWAS803375_Hbrain volume measurement QTL GWAS803375 (human)3e-08brain volume measurementbrain morphological measurement (CMO:0000136)4102005766102005767Human
407131578GWAS780554_HCrohn's disease QTL GWAS780554 (human)1e-15Crohn's disease4102005766102005767Human
407247897GWAS896873_Hapolipoprotein A 1 measurement QTL GWAS896873 (human)2e-41apolipoprotein A 1 measurementblood apolipoprotein AI level (CMO:0000520)4102005766102005767Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS693904_H GCST90264174 Intelligence 223,731 British ancestry individuals ? NR 1E-14 14 rs34592089 N/A intelligence (EFO:0004337)
 PMID:36378351
GWAS699266_H GCST90271813 Ventromedial occipital thickness (unadjusted for global measures) 32,488 European ancestry individuals ? NR 3E-12 11.523 rs34592089 0.1069 cortical thickness (EFO:0004840)
 PMID:36893272
GWAS739355_H GCST90297779 Idiopathic knee osteoarthritis 90,888 European ancestry cases, 263,673 European ancestry controls A 0.06 7E-12 11.155 rs34592089 1.08 osteoarthritis, knee (EFO:0004616)
 PMID:37247657
GWAS780554_H GCST003044 Crohn's disease 5,956 European ancestry cases, 14,927 European ancestry controls ? NR 1E-15 15 rs34592089 N/A Crohn's disease (EFO:0000384)
 PMID:26192919
GWAS801752_H GCST009518 Brain region volumes 19,629 British ancestry individuals ? NR 7E-10 9.155 rs34592089 N/A brain volume measurement (EFO:0006930)
 PMID:31676860
GWAS803375_H GCST009518 Brain region volumes 19,629 British ancestry individuals ? NR 3E-8 7.523 rs34592089 N/A brain volume measurement (EFO:0006930)
 PMID:31676860
GWAS804646_H GCST009518 Brain region volumes 19,629 British ancestry individuals ? NR 3E-13 12.523 rs34592089 N/A brain volume measurement (EFO:0006930)
 PMID:31676860
GWAS810361_H GCST005316 Intelligence (MTAG) 120,934 British ancestry individuals, 127,548 individuals A NR 1E-12 12 rs34592089 0.046348527 intelligence (EFO:0004337)
 PMID:29326435
GWAS814969_H GCST90019497 Aspartate aminotransferase levels 341,246 European ancestry individuals, 5,982 African ancestry individuals, 7,313 South Asian ancestry individuals A NR 3E-27 26.523 rs34592089 0.0545 aspartate aminotransferase measurement (EFO:0004736)
 PMID:33462484
GWAS821650_H GCST90019493 Serum albumin levels 313,032 European ancestry individuals, 5,573 African ancestry individuals, 6,687 South Asian ancestry individuals A NR 2E-24 23.699 rs34592089 0.0535 serum albumin measurement (EFO:0004535)
 PMID:33462484
GWAS829821_H GCST90019500 Calcium levels 313,387 European ancestry individuals, 5,576 African ancestry individuals, 6,696 South Asian ancestry individuals A NR 6E-30 29.222 rs34592089 0.0598 calcium measurement (EFO:0004838)
 PMID:33462484
GWAS868285_H GCST006269 General cognitive ability up to 300,486 European ancestry individuals A NR 3E-16 15.523 rs34592089 8.166 intelligence (EFO:0004337)
 PMID:29844566
GWAS896873_H GCST90019495 Apolipoprotein A1 levels 311,601 European ancestry individuals, 5,550 African ancestry individuals, 6,682 South Asian ancestry individuals A NR 2E-41 40.699 rs34592089 0.0709 apolipoprotein A 1 measurement (EFO:0004614)
 PMID:33462484
GWAS921592_H GCST009685 Hypertension 30,822 British ancestry normal blood pressure individuals, 25,242 British ancestry elevated blood pressure individuals, 50,461 British ancestry stage 1 hypertension individuals, 75,286 British ancestry stage 2 hypertension individuals, 3,754 British ancestry hypertension crisis individuals ? NR 1E-9 9 rs34592089 0.07719143 hypertension (EFO:0000537)
 PMID:31879980
GWAS933265_H GCST90019501 Total cholesterol levels 342,508 European ancestry individuals, 6,014 African ancestry individuals, 7,336 South Asian ancestry individuals A NR 2E-23 22.699 rs34592089 0.0502 total cholesterol measurement (EFO:0004574)
 PMID:33462484
GWAS948765_H GCST90428119 Body mass index 342,566 European ancestry individuals A NR 6E-21 20.222 rs34592089 0.0467757 body mass index (EFO:0004340)
 PMID:38538606
GWAS954160_H GCST90428121 Whole body fat mass (UKB data field 23100) 337,196 European ancestry individuals A NR 1E-13 13 rs34592089 0.036439 fat body mass (EFO:0005409)
 PMID:38538606
GWAS956965_H GCST90019512 Low density lipoprotein cholesterol levels 341,875 European ancestry individuals, 6,003 African ancestry individuals, 7,319 South Asian ancestry individuals A NR 4E-9 8.398 rs34592089 0.0295 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:33462484
GWAS966329_H GCST90019510 High density lipoprotein cholesterol levels 313,372 European ancestry individuals, 5,573 African ancestry individuals, 6,689 South Asian ancestry individuals A NR 3E-51 50.523 rs34592089 0.0791 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:33462484
GWAS988527_H GCST90019524 Urate levels 342,087 European ancestry individuals, 6,011 African ancestry individuals, 7,328 South Asian ancestry individuals A NR 1E-10 10 rs34592089 0.0325 urate measurement (EFO:0004531)
 PMID:33462484
GWAS991318_H GCST90134330 Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy) 20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements ? NR 2E-18 17.699 rs34592089 N/A attention deficit hyperactivity disorder (EFO:0003888)
autism spectrum disorder (EFO:0003756)
intelligence (EFO:0004337)
 PMID:35764056
None Available GCST90448240 Fluid intelligence 337,199 European ancestry individuals ? NR 5E-10 9.302 rs34592089 0.1176 intelligence (EFO:0004337)
 PMID:38434247
Database Acc Id Source(s)
GWAS Catalog GCST90019500 GWAS Catalog

RGD Curation Notes
Note Type Note Reference