GWAS828773_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS828773_H (FEV/FVC ratio QTL GWAS828773 (human)) Homo sapiens

Symbol: GWAS828773_H
Name: FEV/FVC ratio QTL GWAS828773 (human)
RGD ID: 407179797
Trait: FEV/FVC ratio
Measurement Type: forced expiratory volume to forced vital capacity ratio   (CMO:0000241)    
LOD Score: Not Available
P Value: 2.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381162,581,062 - 62,581,063RGD_MAPPER_PIPELINEGRCh38
GRCh371162,348,534 - 62,348,535RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS828773_HHumanforced expiratory volume to forced vital capacity ratio  IAGPrs79021925405850206Based on the EFO term IDGWAS_CATALOGPMID:30595370

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS828773_HHumanFEV/FVC ratio  IAGPrs79021925405850206 GWAS_CATALOGPMID:30595370
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1345565TUT1terminal uridylyl transferase 1, U6 snRNA-specific116257505262591523Human

Position Markers

Peak: (rs79021925)
Human AssemblyChrPosition (strand)Source
GRCh381162,581,062 - 62,581,063RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357380BW64_HBody weight QTL 64 (human)2.2Body weightpercent fat after exercise training116097893786978937Human
407179797GWAS828773_HFEV/FVC ratio QTL GWAS828773 (human)2e-08FEV/FVC ratioforced expiratory volume to forced vital capacity ratio (CMO:0000241)116258106262581063Human
407271049GWAS920025_HBMI-adjusted waist-hip ratio QTL GWAS920025 (human)2e-11BMI-adjusted waist-hip ratio116258106262581063Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS828773_H GCST007080 Lung function (FEV1/FVC) approximately 370,000 European ancestry individuals ? NR 2E-8 7.699 rs79021925 N/A FEV/FVC ratio (EFO:0004713)
 PMID:30595370
GWAS920025_H GCST009858 Waist-to-hip ratio adjusted for BMI 457,690 European ancestry individuals ? NR 2E-11 10.699 rs79021925 N/A BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:31669095
Database Acc Id Source(s)
GWAS Catalog GCST007080 GWAS Catalog

RGD Curation Notes
Note Type Note Reference